Results 181 to 190 of about 95,310 (311)

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

open access: yesAdvanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin   +5 more
wiley   +1 more source

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

open access: yesAdvanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen   +14 more
wiley   +1 more source

Achieving Directional Oil Manipulation by Open Inducing Structure for Electrowetting Displays

open access: yesAdvanced Electronic Materials, EarlyView.
This work introduces an open inducing structure (OIS) fabricated by photoembossing to precisely control oil motion in electrowetting displays (EWDs). The OIS creates local electric field inhomogeneity, guiding directional oil rupture and achieving a 93.8% motion consistency. It significantly lowers the turn‐on voltage and accelerates the response speed,
Qilu Li   +8 more
wiley   +1 more source

The influence of keratometry on the accuracy of intraocular lens formulas in highly myopic eyes. [PDF]

open access: yesBMC Ophthalmol
Li GY   +7 more
europepmc   +1 more source

Modeling the Physical Characteristics of Ultrasound Pretreated Dialium guineense Whole Fruits Using Neural Network Pattern Recognition Model

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
The study of Physical characteristics of agricultural materials is necessary for the design of processes and machines for food production. Length, width, thickness, sphericity, unit mass, and aspect ratio were the physical characteristics of ultrasound pretreated Dialium guineense whole fruits subjected to Neural network modeling.
Mfrekemfon Akpan   +2 more
wiley   +1 more source

Example of the DGS sign HAIRDRY used as a verb

open access: green
Patrick C. Trettenbrein   +3 more
openalex   +1 more source

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