Results 21 to 30 of about 6,848,306 (172)
DHR activates p38 phosphorylation which is important for DHR-induced human plasma cell apoptosis.
(A) Human plasma cell lines LP1, OPM2, RPMI-8226, and U266 were treated with 10 µM of DHR for 30 or 60 min, followed by p38 phosphorylation analysis. The relative phosphorylated level of p38 to GAPDH was calculated by Quality One software.
Biyin Cao (437970) +7 more
core +1 more source
Background: Directional hemispherical reflectance (DHR) is a precise method for evaluating skin reflectance and is widely used in dermatological, photobiological, and cosmetic or pharmaceutical research.
Magdalena Hartman-Petrycka +3 more
doaj +1 more source
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng +10 more
wiley +1 more source
The lobe A is required for dimerization, but not for the Rac GEF activity of DHR-2 domain.
(A) Ribbon diagram of the human DOCK2DHR-2-Rac1 complex. Overall structure (left) and dimerization interface (right) are shown. The coordinates and structure factors have been deposited in the Protein Data Bank (www.pdb.org) under accession code 3B13. (B)
Masao Terasawa (305468) +8 more
core +1 more source
AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
DHR induces human plasma cell apoptosis.
Human plasma cell lines LP1, OPM2, KMS11 and U266 were treated with DHR for 24 h. Induction of apoptosis in human plasma cells by DHR was assessed by Annexin V-FITC and propidium iodide (PI) double staining followed by analysis on a flow cytometer.
Biyin Cao (437970) +7 more
core +1 more source
Due to the difficulty in distinguishing transparent and white foreign fibers from seed cotton in RGB images and in order to improve the recognition ability of deep learning (DL) algorithms for white, transparent, and multi-class mixed foreign fibers with
Yunlong Zhang +3 more
doaj +1 more source
Discrete 2D Material Programming for 3D Shaping and Morphogenesis‐Inspired 4D Bioprinting
Cell‐compatible discrete 2D material programming enables 2‐to‐3D shape transformation and morphogenesis‐inspired 4D bioprinting. By patterning cell‐supportive microdomains within a responsive hydrogel, the approach programs in‐plane growth to encode target metrics.
Fereshteh Family +3 more
wiley +1 more source
DHR activates the ER stress signaling in human plasma cells.
A, LP1 and OPM2 cells were treated with DHR for 24 h, the expression of GRP78 was then detected by immunoblotting. (B) and (C) LP1 and OPM2 cells were treated DHR for different concentrations and time periods before subject to ATF4 and CHOP analysis. (D)
Biyin Cao (437970) +7 more
core +1 more source
Based on the anionic Hofmeister effect, a universal strategy of incorporation of stereo‐π anion BPh4− into a series of Cy5 skeletons to unlock long‐lived charge‐separated states was reported, wherein the weak electronic coupling and low charge recombination driving force hinder the charge recombination process, elevating the oxygen‐independent ROS ...
Xuan Zhao +9 more
wiley +1 more source

