Results 61 to 70 of about 58,310 (198)

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

CORONARY RESERVE AND LEFT VENTRICLE DIASTOLIC FUNCTION AS EVALUATED BY TRANSESOPHAGEAL CARDIAC PACING IN PATIENTS FOLLOWING MYOCARDIAL INFARCTION

Российский кардиологический журнал, 2003
Evaluation to determine the relationship between coronary reserve and myocardium diastolic function was performed in 58 patients surviving a Q-wave myocardial infarction an average of 2. 4 months ago.
A. P. Ivanov, I. A. Elhardt, N. S. Sdobnyakova, V. G. Patrikeyev   +3 more
doaj  

M-mode echocardiography measurements of healthy Brazilian random bred cats

Brazilian Journal of Veterinary Medicine, 2019
To determine the M-mode echocardiography reference measurements for Brazilian random bred cats in Rio de Janeiro, Brazil, Cats presenting for routine care were examined by M-mode echocardiography. Animals with free wall values ​​of the left ventricle and/
Bruno Alberigi, Alexandre José Rodrigues Bendas, Denise do Vale Soares, Carolina Aben Athar, Fabiana Knacfuss Batalha, Renan Salhab Demo, Jonimar da Silva Paiva   +6 more
doaj   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

Advanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu, Leyan Xuan, Yingying Hou, Ting Xie, Jieting Li, Junjie Cai, Siyu Zhang, Yingling Miao, Ning Hou, Gen He, Maobin Xie, Xiyong Yu, Mingen Xu, Guosheng Tang   +13 more
wiley   +1 more source

Left ventricular and left atrial volume ratio assessed by three‐dimensional echocardiography: Novel indices for evaluating age‐related change in left heart chamber size

Physiological Reports, 2019
We hypothesized that left ventricular and left atrial volume ratio (LVLAVR) assessed by three‐dimensional echocardiography (3DE) reflects age‐ and gender‐related change in left chamber size.
Masaaki Takeuchi, Tetsuji Kitano, Yosuke Nabeshima, Yutaka Otsuji, Kyoko Otani   +4 more
doaj   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

The effect of cardiac phase on distractor suppression and motor inhibition in a stop-signal task

Scientific Reports
Past work has shown that stimuli timed to the cardiac systole, the time at which heartbeat feedback is transmitted to the brain, can be more effectively selected from conflicting information.
Amanda C. Marshall, Qiaoyue Ren, Lioba Enk, Junhui Liu, Simone Schütz-Bosbach   +4 more
doaj   +1 more source

Incidental finding of large pneumothorax on Cardiac MR scan

BMC Medical Imaging, 2018
Background We believe this is the first case report of a pneumothorax being identified using cardiac magnetic resonance imaging. This case also illustrates the haemodynamic effect a large pneumothorax can have on right ventricular filling in diastole ...
J. P. M. Andrews, G. McKillop, M. R. Dweck   +2 more
doaj   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source