Results 21 to 30 of about 9,552,162 (207)

Diverse Effects of Natural and Synthetic Surfactants on the Inhibition of Staphylococcus aureus Biofilm

Pharmaceutics, 2021
A major challenge in the biomedical field is the creation of materials and coating strategies that effectively limit the onset of biofilm-associated infections on medical devices. Biosurfactants are well known and appreciated for their antimicrobial/anti-
Gianna Allegrone, Chiara Ceresa, Maurizio Rinaldi, Letizia Fracchia   +3 more
doaj   +1 more source

Priority changes between biofilm exopolysaccharides synthesis and rhamnolipids production are mediated by a c-di-GMP-specific phosphodiesterase NbdA in Pseudomonas aeruginosa

iScience, 2022
Summary: The synthesis of biofilm exopolysaccharides and rhamnolipids (RLs) are two interrelated processes in Pseudomonas aeruginosa, but how bacteria coordinate these two processes remains unclear. We collected a P.
Shixun Liu, Anming Xu, Bin Xie, Fengxue Xin, Weiliang Dong, Jie Zhou, Min Jiang   +6 more
doaj   +1 more source

Targeted killing of myofibroblasts by biosurfactant di-rhamnolipid suggests a therapy against scar formation [PDF]

Scientific Reports, 2016
AbstractPathological myofibroblasts are often involved in skin scarring via generating contractile force and over-expressing collagen fibers, but no compound has been found to inhibit the myofibroblasts without showing severe toxicity to surrounding physiological cells.
Chong Shen, Lifang Jiang, Huawei Shao, Chuangang You, Guoliang Zhang, Sitong Ding, Tingwei Bian, Chunmao Han, Qin Meng   +8 more
openaire   +2 more sources

Oxygen effects on rhamnolipids production by Pseudomonas aeruginosa

Microbial Cell Factories, 2018
Background Rhamnolipids are the most extensively studied biosurfactants and has been successfully used in various areas from bioremediation to industrial fields. Rhamnolipids structural composition decide their physicochemical properties.
Feng Zhao, Rongjiu Shi, Fang Ma, Siqin Han, Ying Zhang   +4 more
doaj   +1 more source

Microbial production of rhamnolipids: opportunities, challenges and strategies

Microbial Cell Factories, 2017
Rhamnolipids are a class of biosurfactants which contain rhamnose as the sugar moiety linked to β-hydroxylated fatty acid chains. Rhamnolipids can be widely applied in many industries including petroleum, food, agriculture and bioremediation etc ...
Huiqing Chong, Qingxin Li
doaj   +1 more source

Designer rhamnolipids by reduction of congener diversity: production and characterization

Microbial Cell Factories, 2017
Background Rhamnolipids are biosurfactants featuring surface-active properties that render them suitable for a broad range of industrial applications. These properties include their emulsification and foaming capacity, critical micelle concentration, and
Till Tiso, Rabea Zauter, Hannah Tulke, Bernd Leuchtle, Wing-Jin Li, Beate Behrens, Andreas Wittgens, Frank Rosenau, Heiko Hayen, Lars Mathias Blank   +9 more
doaj   +1 more source

Analysis of biosurfactants from industrially-viable Pseudomonas strain isolated from crude oil suggests how rhamnolipids congeners affect on emulsification property and antimicrobial activity

Frontiers in Microbiology, 2014
Rhamnolipid biosurfactants produced mainly by Pseudomonas sp. had been reported to possess a wide range of potential industrial application. These biosurfactants are produced as monorhamnolipid (MRL) and di-rhamnolipid (DRL) congeners.
Palashpriya eDas, Xin-Ping eYang, Luyan eMa   +2 more
doaj   +1 more source

Rhamnolipid Biosurfactants—Possible Natural Anticancer Agents and Autophagy Inhibitors

Separations, 2021
Background/Aim: A number of biologically active substances were proved as an alternative to conventional anticancer medicines. The aim of the study is in vitro investigation of the anticancer activity of mono- and di-Rhamnolipids (RL-1 and RL-2) against ...
Severina Semkova, Georgi Antov, Ivan Iliev, Iana Tsoneva, Pavel Lefterov, Nelly Christova, Lilyana Nacheva, Ivanka Stoineva, Lyudmila Kabaivanova, Galya Staneva, Biliana Nikolova   +10 more
doaj   +1 more source

Connecting quorum sensing, c-di-GMP, pel polysaccharide, and biofilm formation in Pseudomonas aeruginosa through tyrosine phosphatase TpbA (PA3885). [PDF]

PLoS Pathogens, 2009
With the opportunistic pathogen Pseudomonas aeruginosa, quorum sensing based on homoserine lactones was found to influence biofilm formation. Here we discern a mechanism by which quorum sensing controls biofilm formation by screening 5850 transposon ...
Akihiro Ueda, Thomas K Wood
doaj   +1 more source

Reduced Intracellular c-di-GMP Content Increases Expression of Quorum Sensing-Regulated Genes in Pseudomonas aeruginosa

Frontiers in Cellular and Infection Microbiology, 2017
Cyclic-di-GMP (c-di-GMP) is an intracellular secondary messenger which controls the biofilm life cycle in many bacterial species. High intracellular c-di-GMP content enhances biofilm formation via the reduction of motility and production of biofilm ...
Song Lin Chua, Yang Liu, Yingying Li, Hui Jun Ting, Gurjeet S. Kohli, Zhao Cai, Pipob Suwanchaikasem, Kelvin Kau Kit Goh, Sean Pin Ng, Tim Tolker-Nielsen, Liang Yang, Liang Yang, Michael Givskov, Michael Givskov   +13 more
doaj   +1 more source