Results 161 to 170 of about 21,413 (223)

Determination of di-(2-ethylhexyl)phthalate in human placenta

Journal of Chromatography A, 1977
A simple method has been devised for the analysis of di-(2-ethylhexyl)phthalate (DEHP) in human placenta which relies entirely on three rapid partition steps prior to gas chromatography with electron capture detection. The use of adsorption chromatography with all its attendant disadvantages for sample clean-up is eliminated in this procedure ...
C F, Poole, D G, Wibberley
openaire   +2 more sources

DI-2-Ethylhexyl Phthalate and Endocrine Disruption: A Review

Current Drug Targets - Immune, Endocrine & Metabolic Disorders, 2004
Esters of o-phthalic acid are widely distributed in the ecosystem. The phthalate acid esters (PAE's) are used as plasticizers in enormous quantities for a variety of industrial uses in the formulation of plastics. They are also used as solvents in certain industrial processes and as vehicles for pesticides and have been described as being among the ...
Giuseppe, Latini, Alberto, Verrotti, Claudio, De Felice   +2 more
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Vitamin E and vitamin C attenuate Di-(2-ethylhexyl) phthalate-induced blood-testis barrier disruption by p38 MAPK in immature SD rats.

Reproductive Toxicology, 2018
As an environmental endocrine disruptor, Di-(2-ethylhexyl) phthalate (DEHP) affects blood-testis barrier (BTB)-associated proteins expression, which compromises BTB integrity and causes infertility. Notably, DEHP-induced testicular toxicity is related to
Lianju Shen, Xiangliang Tang, Yi Wei, Chun-lan Long, B. Tan, Shengde Wu, Mang Sun, Yue Zhou, Xi-ning Cao, G. Wei   +9 more
semanticscholar   +1 more source

Comment on the carcinogenic potential of Di(2‐ethylhexyl) phthalate

Journal of Toxicology and Environmental Health, 1982
Analysis of the carcinogen bioassay of di(2-ethylhexyl) phthalate (DEHP) has shown that the designated maximum tolerated dose was exceeded in the low- and high-dose groups of male rats, in the high-dose group of female rats, and in the low- and high-dose groups of female mice.
S, Northup, L, Martis, R, Ulbricht, J, Garber, J, Miripol, T, Schmitz   +5 more
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Polar metabolites of Di-(2-ethylhexyl)phthalate in the rat

Biochimica et Biophysica Acta (BBA) - General Subjects, 1983
Di-(2-ethylhexyl)phthalate (DEHP) is an important industrial chemical widely used as a plasticizer for vinyl and other plastics. DEHP is extensively metabolized by mammals, different species showing dramatic differences in metabolite distributions. Previous studies of the metabolism in rats led to the suggestion that the enzymatic processes normally ...
P W, Albro, I, Tondeur, D, Marbury, S, Jordan, J, Schroeder, J T, Corbett   +5 more
openaire   +2 more sources

Accumulation and metabolism of di(n-butyl) phthalate (DBP) and di(2-ethylhexyl) phthalate (DEHP) in mature wheat tissues and their effects on detoxification and the antioxidant system in grain.

Science of the Total Environment, 2019
Di(2-ethylhexyl) phthalate (DEHP) and di(n-butyl) phthalate (DBP) are the major phthalic acid esters to be used during the plastic manufacturing process; they have emerged as pollutants that result in serious environmental problems.
Minling Gao, Yalei Xu, Youming Dong, Zhengguo Song, Y. Liu   +4 more
semanticscholar   +1 more source

The Impact of Di(2-ethylhexyl)phthalate on Cancer Progression

Archivum Immunologiae et Therapiae Experimentalis, 2017
Di(2-ethylhexyl)phthalate (DEHP), a widely used plasticizer, mainly serves as an additive to render polyvinyl chloride (PVC) soft and flexible. PVC plastics have become ubiquitous in our modern society. Yet, the leaching of DEHP from PVC-based consumables ultimately results in the deposition in certain tissues via inadvertent applications. Health risks
Chon-Kit Chou, Ya-Ting Yang, Ho-Chun Yang, Shih-Shin Liang, Tsu-Nai Wang, Po-Lin Kuo, Hui-Min David Wang, Eing-Mei Tsai, Chien-Chih Chiu   +8 more
openaire   +2 more sources

Reversibility of the Chronic Effects of Di(2-ethylhexyl)phthalate

Toxicologic Pathology, 2001
Fischer-344 rats treated with 12,500 ppm (728 and 879 mg/kg/d for male and females, respectively) and B6C3F 1 mice treated with 6,000 ppm (1,227 and 1,408 mg/kg/d, respectively) di(2-ethylhexyl)phthalate (DEHP) in the diet for 78 weeks were allowed to recover for an additional 26 weeks on ...
R M, David, M R, Moore, D C, Finney, D, Guest   +3 more
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Di(2-ethylhexyl) phthalate (DEHP) and thyroid: biological mechanisms of interference and possible clinical implications

Environmental science and pollution research international, 2021
Xueting Zhang, Wen Qi, Qi Xu, Xu Li, Liting Zhou, Lin Ye   +5 more
semanticscholar   +1 more source

Excretion and metabolism of di(2-ethylhexyl)-phthalate in man

Xenobiotica, 1985
Di-(2-ethylhexyl)phthalate (DEHP) taken orally by two volunteers (30 mg each) was excreted in the urine to the extent of 11 and 15% of dose. After enzymic hydrolysis the urinary metabolites (derivatives of mono (2-ethylhexyl)phthalate) were methylated and identified by g.l.c.-mass spectrometry (C.I.), and the quantitative distribution of conjugated and
P, Schmid, C, Schlatter
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