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No background concentrations of di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate in blood of rats

open access: yesArchives of Toxicology, 2001
We measured the background levels of di(2-ethylhexyl) phthalate (DEHP) and its hydrolytic metabolite mono(2-ethylhexyl) phthalate (MEHP) in blood from naive female Sprague-Dawley rats and in de-ionized charcoal-purified water using an analytical procedure that is based on sample treatment with acetonitrile, n-hexane extraction and analysis by gas ...
W, Kessler   +3 more
openaire   +3 more sources
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Enzymatic hydrolysis of Di-(2-ethylhexyl) phthalate by lipases

Lipids and Lipid Metabolism, 1973
Abstract Di-(2-ethylhexyl) phthalate was hydrolyzed by lipases from a variety of rat tissues. Of the preparations studied, only glycerol-ester hydrolase (pancreatic lipase, EC 3.1.1.3) and sterol-ester -hydrolase (cholesteryl ester hydrolase, EC 3.1.1.13) were unable to hydrolyze the phthalate diester. However, out of 15 different tissue preparations,
Phillip W Albro, P W Albro
exaly   +3 more sources

Effect of sterilization process on the formation of mono(2-ethylhexyl)phthalate from di(2-ethylhexyl)phthalate

Journal of Pharmaceutical and Biomedical Analysis, 2006
The risk assessment of di(2-ethylhexyl)phthalate (DEHP) migrating from polyvinyl chloride (PVC) medical devices is an important issue. Many studies have been conducted to determine the level of DEHP migration. A recent report has indicated that DEHP in blood bags is hydrolyzed by esterase into mono(2-ethylhexyl)phthalate (MEHP).
Migaku Kawaguchi
exaly   +3 more sources

Simultaneous Determination of Di(2-Ethylhexyl)phthalate and Mono(2-Ethylhexyl)phthalate in Human Plasma by High-Performance Liquid Chromatography

open access: yesAnalytical Letters, 2003
A method for the simultaneous determination of di(2-ethylhexyl)phthalate and its major metabolite mono(2-ethylhexyl)phthalate in human plasma by high-performance liquid chromatography is described.
Pietro Mazzeo, Giuseppe Carlucci
exaly   +2 more sources

Metabolism of DI(2=Ethylhexyl)Phthalate

Drug Metabolism Reviews, 1989
(1989). Metabolism of DI(2=Ethylhexyl)Phthalate. Drug Metabolism Reviews: Vol. 21, No. 1, pp. 13-34.
P W, Albro, S R, Lavenhar
openaire   +2 more sources

Di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate in media for in vitro fertilization

Chemosphere, 2012
In vitro fertilization (IVF) is one of the most important treatments of infertility to provide a chance of conceiving. In IVF treatment, sperm are washed and motile sperm are isolated with sperm washing media (SWM) for the purpose of fertilization; fertilized ova are then incubated for a maximum of 5 or 6d in media for IVF (IVFM).
Satoshi, Takatori   +5 more
openaire   +2 more sources

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