Results 91 to 100 of about 5,587,889 (314)

Illness perceptions of Libyans with T2DM and their influence on medication adherence: a study in a diabetes center in Tripoli. [PDF]

, 2015
BackgroundThe surrounding environment influences the constitution of illness perceptions. Therefore, local research is needed to examine how Libyan diabetes patients perceive diabetes and how their perceptions influence their medication adherence ...
Ashur, Sana Taher, Bosseri, Soad, Morisky, Donald E, Shah, Shamsul Azhar, Shamsuddin, Khadijah   +4 more
core   +3 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

The Role of Diabetes Co-Morbidity for Tuberculosis Treatment Outcomes: A Prospective Cohort Study from Mwanza, Tanzania. [PDF]

, 2012
Due to the association between diabetes and pulmonary tuberculosis (TB), diabetes may threaten the control of TB. In a prospective cohort study nested in a nutrition trial, we investigated the role of diabetes on changes in anthropometry, grip strength ...
Aabye, Martine Grosos, Andersen, Åse Bengård, Changalucha, John, Christensen, Dirk Lund, Faurholt-Jepsen, Daniel, Faurholt-Jepsen, Maria, Friis, Henrik, Kidola, Jeremiah, Krarup, Henrik, Martinussen, Torben, Praygod, George, Range, Nyagosya, Witte, Daniel Rinse   +12 more
core   +2 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Looking into Concept Explanation Methods for Diabetic Retinopathy Classification [PDF]

Machine.Learning.for.Biomedical.Imaging. 2 (2024)
Diabetic retinopathy is a common complication of diabetes, and monitoring the progression of retinal abnormalities using fundus imaging is crucial. Because the images must be interpreted by a medical expert, it is infeasible to screen all individuals with diabetes for diabetic retinopathy.
arxiv   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Development of deep learning algorithms to categorize free-text notes pertaining to diabetes: convolution neural networks achieve higher accuracy than support vector machines [PDF]

arXiv, 2018
Health professionals can use natural language processing (NLP) technologies when reviewing electronic health records (EHR). Machine learning free-text classifiers can help them identify problems and make critical decisions. We aim to develop deep learning neural network algorithms that identify EHR progress notes pertaining to diabetes and validate the
arxiv  

The effects of structured intensive diabetes education programs in patients with type 2 diabetes [PDF]

, 2010
The Centers for Disease Control and Prevention (CDC) estimates morbidity rates for diabetes (diagnosed or undiagnosed) at 10% of non-institutionalized adults 20 years and older. In addition, there were 28.6 million ambulatory care visits with diabetes as
Diljak, Michael S.
core   +1 more source

Diabetes and Risk of Non-Hodgkin's Lymphoma [PDF]

, 2011
OBJECTIVE: To examine the epidemiologic association between diabetes and risk of non-Hodgkin's lymphoma (NHL). RESEARCH DESIGN AND METHODS: We searched MEDLINE for observational studies on the association between diabetes and NHL in adults using the ...
Castillo, Jorge, Mitri, Joanna, Pittas, Anastassios G.   +2 more
core   +2 more sources

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source