Results 301 to 310 of about 4,039,932 (316)

ROS‐Responsive Microneedle Patches Enable Peri‐Lacrimal Gland Therapeutic Administration for Long‐Acting Therapy of Sjögren's Syndrome‐Related Dry Eye

Advanced Science, EarlyView.
A new strategy for constructing smart gel‐based MN patches is developed to overcome the insufficient drug delivery of eye drops to the lacrimal gland. The gel‐based MN patches achieved long‐acting drug release in a ROS‐responsive manner, and separable base in a temperature‐responsive manner.
Jingqing Mu, Xiangyu Ding, Yapeng Song, Baoyue Mi, Xiaolong Fang, Baihua Chen, Bin Yao, Xuguang Sun, Xiaoyong Yuan, Shutao Guo, Xia Hua   +10 more
wiley   +1 more source

Impact of health systems interventions in primary health settings on type 2 diabetes care and health outcomes among adults in West Africa: A systematic review. [PDF]

PLoS One
Bondzie EPK, Amarteyfio K, Jahan Y, Afun NEE, Agyekum MP, Tapsoba L, Balabanova D, Mirzoev T, Agyepong I.   +8 more
europepmc   +1 more source

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

The use of statins are associated with an increased risk of new-onset diabetes in patients with hypertension and obstructive sleep apnoea, a longitudinal study. [PDF]

Diabetol Metab Syndr
Wang H, Heizhati M, Li N, Gan L, Yao L, Li M, Cai L, Li X, Aierken X, Yu D, Liu M, Maitituersun A, Nuermaimaiti Q, Nusufujiang A, Hong J.   +14 more
europepmc   +1 more source

3‐D Sustained‐Release Culture Carrier Alleviates Rat Intervertebral Disc Degeneration by Targeting STING in Transplanted Skeletal Stem Cells

Advanced Science, EarlyView.
Schematic representation of mechanisms by which the 3‐D sustained‐release culture carrier prevents accumulation of ROS by continuously releasing C‐176@PDA‐NPs and inhibiting the cGAS‐STING activated by sudden hypoxia, thereby preventing ferroptosis and promoting differentiation in SSCs and ultimately attenuating IVDD progression.
Liwen Luo, Shiyu Zhang, Junfeng Gong, Ji Zhang, Peng Xie, Jun Yin, MengJie Zhang, Cong Zhang, Hong Chen, Yao Liu, Bing Ni, Changqing Li, Zhiqiang Tian   +12 more
wiley   +1 more source

Wave in Pediatric Type 1 Diabetes Incidence After the Emergence of COVID-19: Peak and Trough Patterns in German Youth-A Population-Based Study From the Prospective Multicenter DPV Registry. [PDF]

Diabetes Care
Kamrath C, Eckert AJ, Lignitz S, Hillenbrand N, Dost A, Warncke K, Klose D, Grohmann-Held K, Holl RW, Rosenbauer J.   +9 more
europepmc   +1 more source

Large‐Scale Plasma Proteomics to Profile Pathways and Prognosis of Chronic Pain

Advanced Science, EarlyView.
This study delineates both common and site‐specific proteins linked to various chronic pain conditions, elucidating their implications across molecular pathways and health status. These findings, particularly those proteins with genetic causal links to pain or predictive capabilities, have the potential to significantly benefit both research and ...
Ze‐Yu Li, Qing Ma, Jie Zhang, Rui‐Ying Yin, Jia You, Qi‐Zheng Hao, Xin‐Rui Wu, Ju‐Jiao Kang, Lin‐Bo Wang, Yue‐Ting Deng, Yu‐Zhu Li, Chun Shen, Bang‐Sheng Wu, Jian‐Feng Feng, Yi‐Heng Tu, Xiao Xiao, Jin‐Tai Yu, Wei Cheng   +17 more
wiley   +1 more source

Evaluation of a Continuous Glucose Monitoring-Based Insulin Titration Protocol for Inpatients With Type 2 Diabetes in Nonintensive Care Unit Settings. [PDF]

J Diabetes Sci Technol
Olsen MT, Pedersen-Bjergaard U, Jensen SH, Rasmussen LM, Klarskov CK, Lindegaard B, Andersen JA, Gottlieb H, Lunding S, Hansen KB, Kristensen PL.   +10 more
europepmc   +1 more source

Association of Diabetic Ketoacidosis at Onset, Diabetes Technology Uptake, and Clinical Outcomes After 1 and 2 Years of Follow-up: A Collaborative Analysis of Pediatric Registries Involving 9,269 Children With Type 1 Diabetes From Nine Countries. [PDF]

Diabetes Care
Dovc K, Neuman V, Gita G, Cherubini V, Alonso GT, Fritsch M, Boettcher C, de Beaufort C, Holl RW, de Bock M.   +9 more
europepmc   +1 more source

An effective PO-RSNN and FZCIS based diabetes prediction and stroke analysis in the metaverse environment. [PDF]

Sci Rep
Karpagam M, Sarumathi S, Maheshwari A, Vijayalakshmi K, Jagadeesh K, Bereznychenko V, Narayanamoorthi R.   +6 more
europepmc   +1 more source