Results 211 to 220 of about 1,073,655 (357)

Social Network Characteristics Are Associated With Type 2 Diabetes Complications: The Maastricht Study [PDF]

, 2018
Stephanie Brinkhues, Nicole H. T. M. Dukers–Muijrers, Christian J. P. A. Hoebe, Carla Kallen, Annemarie Koster, Ronald M.A. Henry, Coen D.A. Stehouwer, Paul H. M. Savelkoul, Nicolaas C. Schaper, Miranda T. Schram   +9 more
openalex   +1 more source

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

Insights into the molecular underpinning of type 2 diabetes complications. [PDF]

Hum Mol Genet
Singh A, Bocher O, Zeggini E.
europepmc   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Associations of genetic factors with vascular diabetes complications: an umbrella review. [PDF]

J Glob Health
Zhou X, Yang N, Xu W, Li X, Spiliopoulou A, Theodoratou E.   +5 more
europepmc   +1 more source

Bifurcate Regulation of Hematopoietic Homeostasis and Bone Osteogenesis by VHL‐HIF2α‐Controlled Adipocyte Function

Advanced Science, EarlyView.
The VHL‐HIF2α (VHL is Von Hippel‐Lindau) axis in adipocytes differentially regulates hematopoiesis and bone formation through stem cell factor (SCF) and chemerin, respectively. This hypoxia‐responsive pathway in adipocytes establishes a systemic signaling network with HSCs and MSCs to maintain tissue homeostasis, revealing a targetable axis for ...
Qian Li, Jia Li, Anshu Tang, Cong Li, Chao Zhang, Congcong Zhang, Yun‐Cai Liu   +6 more
wiley   +1 more source

Predictive ability of visit-to-visit glucose variability on diabetes complications. [PDF]

BMC Med Inform Decis Mak
Teh XR, Looareesuwan P, Pattanaprateep O, Pattanateepapon A, Attia J, Thakkinstian A.   +5 more
europepmc   +1 more source

Microvascular and Macrovascular Complications in Young-onset Type 2 Diabetes in a Tertiary Health Institution in Malaysia in Comparison with Type 1 Diabetes Patients [PDF]

, 2016
Kim Piow Lim, Siew Hui Foo, Kean Yew Liew, Kavitha Arumugam, Nurafna Mohd Jaafar, Yung Zhuang Choo, Yen Shen Wong   +6 more
openalex   +1 more source

Association of plasma fibrinogen and development of complications in type 2 diabetes mellitus

, 2023
Het V. Patel, Rajesh S. Sumple, Pooja Harshitha K., Kshitij R. Sumple   +3 more
openalex   +2 more sources

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

Advanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue, Jialu Zhuang, Taotao Fan, Songtao Tang, Junjun Wang, Xiaohui Liu, Jian Liu, Jin Shi, Jiaji Li, Wanjun Li, Danyou Hu, Xiaoqian Zhang, Hua Wang, Guiyang Zhang   +13 more
wiley   +1 more source