Results 221 to 230 of about 2,935,189 (309)

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

Advanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng, Jianhua Wang, Tao Zhang, Xiaofan Fan, Jinxiu Guo, Shiyuan Zhao, Wenxue Sun, Pei Jiang   +7 more
wiley   +1 more source

The Relationship Between Body Fat Percentage, Anthropometric Measurements, and Diabetes Complications in Female Patients with Type 2 Diabetes. [PDF]

J Clin Med
Akinci UN, Dogan C, Tural E, Dayan A.
europepmc   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source

Insights into the molecular underpinning of type 2 diabetes complications. [PDF]

Hum Mol Genet
Singh A, Bocher O, Zeggini E.
europepmc   +1 more source

Injectable Peptide‐Based Functional Amyloid Hydrogels as Tunable Depots for Sustained Drug Delivery

Advanced Science, EarlyView.
An injectable and tunable peptide‐based functional amyloid hydrogel provides sustained insulin release while preserving insulin stability and bioactivity. The hydrogel enables prolonged glycemic regulation in vivo, exhibits excellent biocompatibility, and shows no detectable IAPP and α‐Syn heterologous cross‐seeding, highlighting its potential as a ...
Ranjit Shaw, Niyamat M. A. Chimthanawala, Shouvik Manna, Sadhana Sathaye, Samir K. Maji   +4 more
wiley   +1 more source

Response to commentary on 'A prediction model for diabetes complications using the Kokuho Database and its application to public health services in Japan'. [PDF]

J Diabetes Investig
Chiba S, Itoga T, Asada K, Yabe D.
europepmc   +1 more source

Fully Integrated Wearable Ultrasound System for Continuous Promotion of Wound Healing

Advanced Science, EarlyView.
A wearable ultrasound system integrating a drug‐loaded patch and a miniaturized driving circuit is presented to achieve noninvasive, on‐demand stimulation, enabling programmable antibacterial activity, inflammation modulation, and accelerated wound closure through enhanced cell migration and collagen remodeling.
Faxing Zou, Yansen Wang, Yong Luo, Wenxuan Zhuang, Mingyu Zhu, Min Long, Qingzhou Liu, Tailin Xu   +7 more
wiley   +1 more source

Associations of genetic factors with vascular diabetes complications: an umbrella review. [PDF]

J Glob Health
Zhou X, Yang N, Xu W, Li X, Spiliopoulou A, Theodoratou E.   +5 more
europepmc   +1 more source

Type 1 Diabetes Is a Barrier to Obesity Treatment: Patient Insights From a Mixed-Methods Study

Journal of Obesity
Ebaa Al Ozairi, Dalal Alsaeed, Alvin Mondoh, Etab Taghadom, Mohammad Irshad, Dherar Alroudhan, Jumana Al Kandari, Werd Al-Najim, Carel W. le Roux   +8 more
doaj   +1 more source

LepR‐Lineage Cells Represent the Main Target of the Nociceptive CGRP Pathway in White Adipose Tissue Browning

Advanced Science, EarlyView.
Regulation of WAT Browning and UCP1 Expression in LepR‐MSCs of Inguinal WAT by Nociceptive CGRP and Sympathetic Nervous System (SNS) Noradrenaline (NE). ABSTRACT Sympathetic innervation regulates white adipose tissue (WAT) browning; however, the roles of nociceptive neurons and their associated target cells remain unknown.
Yu‐Ting Yen, May Chien, Yan‐Tung Kiu, Ru‐Sing Lee, Hui‐Teng Cheng, Shuei‐Liong Lin, Dong‐Chuan Wu, I‐Hsien Teng, Yi‐Wen Lin, Yi‐Hung Chen, Mien‐Chie Hung, Shih‐Chieh Hung   +11 more
wiley   +1 more source