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MicroRNAs in Diabetic Kidney Disease [PDF]

open access: yesInternational Journal of Endocrinology, 2014
Rapid growth of diabetes and diabetic kidney disease exerts a great burden on society. Owing to the lack of effective treatments for diabetic kidney disease, treatment relies on drugs that either reduces its progression or involve renal replacement ...
Rong Li   +3 more
doaj   +3 more sources

Renal biopsy in diabetic patients: Histopathological and clinical correlations [PDF]

open access: yesRevista Portuguesa de Nefrologia e Hipertensão, 2021
Introduction: Diabetes is the leading cause of chronic kidney disease and end-stage kidney disease worldwide. A kidney biopsy in a diabetic patient must be considered when non-diabetic renal disease is suspected, such as in the presence of a rapid ...
Joana Paixão   +10 more
doaj   +1 more source

Metabolic phenotypes and risk of end-stage kidney disease in patients with type 2 diabetes

open access: yesFrontiers in Endocrinology, 2023
BackgroundObesity often initiates or coexists with metabolic abnormalities. This study aimed to investigate the pathological characteristics and the independent or mutual relations of obesity and metabolic abnormalities with end-stage kidney disease ...
Lijun Zhao   +12 more
doaj   +1 more source

Intravitreal vascular endothelial growth factor inhibitors did not increase the risk of end-stage renal disease in patients with biopsy-proven diabetic kidney disease based on matched study

open access: yesFrontiers in Pharmacology, 2022
Purpose: This study aimed to investigate the effects of intravitreal (IVT) VEGFi on long-term renal outcomes in patients with biopsy-proven diabetic kidney disease (DKD).Patients and methods: Patients prescribed IVT VEGFi (VEGFi group) were enrolled from
Xiang Xiao   +19 more
doaj   +1 more source

Lower bile acids as an independent risk factor for renal outcomes in patients with type 2 diabetes mellitus and biopsy-proven diabetic kidney disease

open access: yesFrontiers in Endocrinology, 2022
AimsAbnormalities of glucolipid metabolism are critical mechanisms involved in the progression of diabetic kidney disease (DKD). Bile acids have an essential role in regulating glucolipid metabolism.
Xiang Xiao   +18 more
doaj   +1 more source

Research progress of single nucleotide polymorphisms and immune cells in diabetic kidney disease [PDF]

open access: yesJichu yixue yu linchuang, 2022
Diabetic kidney disease has obvious family aggregation and ethnic differences, some single nucleotide polymorphisms (SNPs) related to the susceptibility of diabetic kidney disease have been identified, especially engulfment and cell motility 1 (ELMO1 ...
GUO Meng-ran, MIN Hang, YE Yue, XU Xiao-shuang, ZHEN Dong-hu
doaj   +1 more source

Exploring molecular targets in diabetic kidney disease [PDF]

open access: yesKidney Research and Clinical Practice, 2022
Diabetic kidney disease is the leading cause of end-stage kidney disease, and it remains a major challenge. Many factors, such as glomerular hyperfiltration, oxidative stress, inflammation, hypoxia, and epigenetics, are associated with the progression of
Sayako Maruno   +2 more
doaj   +1 more source

Association between serum uric acid and renal outcome in patients with biopsy-confirmed diabetic nephropathy

open access: yesEndocrine Connections, 2021
Objective: To investigate the relationship between serum uric acid (SUA) level and renal outcome in patients with type 2 diabetes mellitus (T2DM) and diabetic nephropathy (DN). Methods: A total of 393 Chinese patients with T2DM and biopsy-proven DN and
Yutong Zou   +16 more
doaj   +1 more source

Diabetic Kidney Disease [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2017
Diabetic kidney disease (DKD) is a major cause of ESRD. Management includes prudent BP and glycemic control, nutritional counseling, and lifestyle modifications, including exercise, weight loss, and smoking cessation. Renin-angiotensin system (RAS) blockade using angiotensin-converting enzyme (ACE)
Lili, Tong, Sharon G, Adler
openaire   +2 more sources

The Vascular Disease of Diabetic Kidney Disease

open access: yesCardiorenal Medicine, 2022
<b><i>Background:</i></b> The incidence of cardiovascular disease (CVD) is increased in patients with diabetic kidney disease (DKD). <b><i>Summary:</i></b> Aortic stiffness is a well-accepted biomarker for cardiovascular (CV) events in all stages of CKD.
Paolo Lentini   +9 more
openaire   +4 more sources

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