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Nature Reviews Disease Primers, 2015 The kidney is arguably the most important target of microvascular damage in diabetes. A substantial proportion of individuals with diabetes will develop kidney disease owing to their disease and/or other co-morbidity, including hypertension and ageing-related nephron loss.
Thomas, Merlin C. +8 more
exaly +12 more sources
InnovAiT: Education and inspiration for general practice, 2023 Diabetes is the leading cause of chronic kidney disease and end stage renal disease (ESRD) globally. Diabetic kidney disease, previously known as diabetic nephropathy, is a general term used for deterioration of kidney function in patients with diabetes.
Dr Apurva Mishra, Dr Wendy Watson
+6 more sources
Renal biopsy in diabetic patients: Histopathological and clinical correlations [PDF]
Revista Portuguesa de Nefrologia e Hipertensão, 2021 Introduction: Diabetes is the leading cause of chronic kidney disease and end-stage kidney disease worldwide. A kidney biopsy in a diabetic patient must be considered when non-diabetic renal disease is suspected, such as in the presence of a rapid ...
Joana Paixão +10 more
doaj +1 more source
Metabolic phenotypes and risk of end-stage kidney disease in patients with type 2 diabetes
Frontiers in Endocrinology, 2023 BackgroundObesity often initiates or coexists with metabolic abnormalities. This study aimed to investigate the pathological characteristics and the independent or mutual relations of obesity and metabolic abnormalities with end-stage kidney disease ...
Lijun Zhao +12 more
doaj +1 more source
Clinical Journal of the American Society of Nephrology, 2017 Diabetic kidney disease (DKD) is a major cause of ESRD. Management includes prudent BP and glycemic control, nutritional counseling, and lifestyle modifications, including exercise, weight loss, and smoking cessation. Renin-angiotensin system (RAS) blockade using angiotensin-converting enzyme (ACE)
Lili, Tong, Sharon G, Adler
openaire +3 more sources
New Diabetes Therapies and Diabetic Kidney Disease Progression:the Role of SGLT-2 Inhibitors [PDF]
, 2018 Purpose of Review Sodium-glucose co-transporter 2 (SGLT-2) inhibitors have emerged as a promising drug class for the treatment of diabetic kidney disease.
Dekkers, Claire C. J. +2 more
core +12 more sources
Frontiers in Pharmacology, 2022 Purpose: This study aimed to investigate the effects of intravitreal (IVT) VEGFi on long-term renal outcomes in patients with biopsy-proven diabetic kidney disease (DKD).Patients and methods: Patients prescribed IVT VEGFi (VEGFi group) were enrolled from
Xiang Xiao +19 more
doaj +1 more source
Frontiers in Endocrinology, 2022 AimsAbnormalities of glucolipid metabolism are critical mechanisms involved in the progression of diabetic kidney disease (DKD). Bile acids have an essential role in regulating glucolipid metabolism.
Xiang Xiao +18 more
doaj +1 more source
Research progress of single nucleotide polymorphisms and immune cells in diabetic kidney disease [PDF]
Jichu yixue yu linchuang, 2022 Diabetic kidney disease has obvious family aggregation and ethnic differences, some single nucleotide polymorphisms (SNPs) related to the susceptibility of diabetic kidney disease have been identified, especially engulfment and cell motility 1 (ELMO1 ...
GUO Meng-ran, MIN Hang, YE Yue, XU Xiao-shuang, ZHEN Dong-hu
doaj +1 more source
Nonproteinuric diabetic kidney disease [PDF]
Clinical and Experimental Nephrology, 2020 AbstractProteinuria has been considered to be the hallmark of diabetic kidney disease and to precede renal function loss. However, it has become clear that a substantial proportion of patients either with type 1 diabetes or type 2 diabetes have renal function loss without proteinuria, known as nonproteinuric diabetic kidney disease.
Yamanouchi, Masayuki +4 more
openaire +2 more sources