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Swiss Medical Weekly, 2023 Diabetic kidney disease is highly prevalent in patients with type 2 diabetes and is a major cause of end-stage renal disease in Switzerland. Patients with diabetic kidney disease are among the most complex patients in diabetes care.
Anne Zanchi +7 more
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Use of Anti-Diabetic Agents in Non-Diabetic Kidney Disease: From Bench to Bedside
Life, 2021 New drugs were recently developed to treat hyperglycemia in patients with type 2 diabetes mellitus (T2D). However, metformin remains the first-line anti-diabetic agent because of its cost-effectiveness.
Sungjin Chung, Gheun-Ho Kim
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The Podocyte in Diabetic Kidney Disease [PDF]
The Scientific World JOURNAL, 2009 Approaching epidemic levels, diabetic kidney disease (DKD) is now the leading cause of end-stage renal disease (ESRD). Microalbuminuria is an early clinical marker of DKD that results from damage to the glomerular filtration barrier at the level of the highly differentiated glomerular podocyte cells.
Erin Stitt-Cavanagh +2 more
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Research progress on ferroptosis in diabetic kidney disease
Frontiers in Endocrinology, 2022 Ferroptosis is a newly discovered form of cell death that differs from other forms of regulated cell death at morphological, biochemical, and genetic levels, and is characterized by iron-dependent accumulation of lipid peroxides.
You Wu, Yan Chen
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Cells, 2021 Diabetic kidney disease (DKD) is a frequent, potentially devastating complication of diabetes mellitus. Several factors are involved in its pathophysiology.
Claudio D. Gonzalez +4 more
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Advanced-Glycation End-Products Induce Podocyte Injury and Contribute to Proteinuria
Frontiers in Medicine, 2021 The prevalence of diabetes reaches epidemic proportions. Diabetes is the leading cause of end-stage kidney disease (ESKD) since 30–40% of diabetic patients develop diabetic nephropathy.
Rajkishor Nishad +6 more
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Incretins in the Therapy of Diabetic Kidney Disease [PDF]
International Journal of Molecular Sciences, 2021 Diabetic kidney disease is a microvascular complication that occurs in patients with diabetes. It is strongly associated with increased risk of kidney replacement therapy and all-cause mortality. Incretins are peptide hormones derived from the gastrointestinal tract, that besides causing enhancement of insulin secretion after oral glucose intake ...
Agnieszka Przezak +2 more
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Vasopressin and Diabetic Kidney Disease [PDF]
Annals of Nutrition and Metabolism, 2018 <b><i>Background:</i></b> Diabetic nephropathy has become the most common cause of chronic kidney disease (CKD). Despite the progress accomplished in therapy, the prevalence of renal disorders remains high. Some modifiable factors driving the increase in incidence of CKD, in diabetes and other settings, might have been ...
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NAD+ Homeostasis in Diabetic Kidney Disease [PDF]
Frontiers in Medicine, 2021 The redox reaction and energy metabolism status in mitochondria is involved in the pathogenesis of metabolic related disorder in kidney including diabetic kidney disease (DKD). Nicotinamide adenine dinucleotide (NAD+) is a cofactor for redox reactions and energy metabolism in mitochondria.
Jing Xu +5 more
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Biomarkers of diabetic kidney disease [PDF]
Diabetologia, 2018 Diabetic kidney disease (DKD) remains one of the leading causes of reduced lifespan in diabetes. The quest for both prognostic and surrogate endpoint biomarkers for advanced DKD and end-stage renal disease has received major investment and interest in recent years.
Colhoun, Helen M +1 more
openaire +3 more sources