Results 21 to 30 of about 195,915 (258)
Use of Anti-Diabetic Agents in Non-Diabetic Kidney Disease: From Bench to Bedside
Life, 2021 New drugs were recently developed to treat hyperglycemia in patients with type 2 diabetes mellitus (T2D). However, metformin remains the first-line anti-diabetic agent because of its cost-effectiveness.
Sungjin Chung, Gheun-Ho Kim
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Research progress on ferroptosis in diabetic kidney disease
Frontiers in Endocrinology, 2022 Ferroptosis is a newly discovered form of cell death that differs from other forms of regulated cell death at morphological, biochemical, and genetic levels, and is characterized by iron-dependent accumulation of lipid peroxides.
You Wu, Yan Chen
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Cells, 2021 Diabetic kidney disease (DKD) is a frequent, potentially devastating complication of diabetes mellitus. Several factors are involved in its pathophysiology.
Claudio D. Gonzalez +4 more
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Advanced-Glycation End-Products Induce Podocyte Injury and Contribute to Proteinuria
Frontiers in Medicine, 2021 The prevalence of diabetes reaches epidemic proportions. Diabetes is the leading cause of end-stage kidney disease (ESKD) since 30–40% of diabetic patients develop diabetic nephropathy.
Rajkishor Nishad +6 more
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Use of Readily Accessible Inflammatory Markers to Predict Diabetic Kidney Disease
Frontiers in Endocrinology, 2018 Diabetic kidney disease is a common complication of type 1 and type 2 diabetes and is the primary cause of end-stage renal disease in developed countries. Early detection of diabetic kidney disease will facilitate early intervention aimed at reducing the
Lauren Winter +11 more
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Vasopressin and Diabetic Kidney Disease [PDF]
Annals of Nutrition and Metabolism, 2018 <b><i>Background:</i></b> Diabetic nephropathy has become the most common cause of chronic kidney disease (CKD). Despite the progress accomplished in therapy, the prevalence of renal disorders remains high. Some modifiable factors driving the increase in incidence of CKD, in diabetes and other settings, might have been ...
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NAD+ Homeostasis in Diabetic Kidney Disease [PDF]
Frontiers in Medicine, 2021 The redox reaction and energy metabolism status in mitochondria is involved in the pathogenesis of metabolic related disorder in kidney including diabetic kidney disease (DKD). Nicotinamide adenine dinucleotide (NAD+) is a cofactor for redox reactions and energy metabolism in mitochondria.
Jing Xu +5 more
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Diabetic kidney disease: the kidney disease relevant to individuals with diabetes
Clinical and Experimental NephrologyAbstractIn individuals with diabetes, chronic kidney disease (CKD) is a major comorbidity. However, it appears that there is worldwide confusion regarding which term should be used to describe CKD complicated with diabetes: diabetic nephropathy, diabetic kidney disease (DKD), CKD with diabetes, diabetes and CKD, etc.
Keizo Kanasaki +2 more
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Incretins in the Therapy of Diabetic Kidney Disease [PDF]
International Journal of Molecular Sciences, 2021 Diabetic kidney disease is a microvascular complication that occurs in patients with diabetes. It is strongly associated with increased risk of kidney replacement therapy and all-cause mortality. Incretins are peptide hormones derived from the gastrointestinal tract, that besides causing enhancement of insulin secretion after oral glucose intake ...
Agnieszka Przezak +2 more
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Frontiers in EndocrinologyPurposeTo evaluate the all-cause mortality rate and renal outcomes in patients with diabetes and chronic kidney disease (CKD) following hospital discharge for COVID-19.MethodsThis single-center prospective observational study included 187 discharged ...
Enrong Ran +16 more
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