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Mitophagy in Diabetic Kidney Disease [PDF]
Frontiers in Cell and Developmental Biology, 2021 Diabetic kidney disease (DKD) is the most common cause of end-stage kidney disease worldwide and is the main microvascular complication of diabetes. The increasing prevalence of diabetes has increased the need for effective treatment of DKD and identification of new therapeutic targets for better clinical management.Xiaofeng Zhang, Jing Feng, Xia Li, Dan Wu, Qian Wang, Shuyu Li, Changhua Shi +6 moreopenaire +3 more sourcesAddition of glomerular lesion severity improves the value of anemia status for the prediction of renal outcomes in Chinese patients with type 2 diabetes
Renal Failure, 2022 We aimed to determine the utility of biopsy data and anemia for the prediction of renal outcomes in Chinese patients with type 2 diabetes. In total, 441 Chinese patients with type 2 diabetes and biopsy-confirmed diabetic nephropathy (DN) were enrolled in Lijun Zhao, Qianqian Han, Li Zhou, Lin Bai, Yiting Wang, Yucheng Wu, Honghong Ren, Yutong Zou, Shuangqing Li, Qiaoli Su, Huan Xu, Lin Li, Zhonglin Chai, Mark E. Cooper, Nanwei Tong, Jie Zhang, Fang Liu +16 moredoaj +1 more sourcePathomechanisms of Diabetic Kidney Disease [PDF]
Journal of Clinical Medicine, 2023 The worldwide occurrence of diabetic kidney disease (DKD) is swiftly rising, primarily attributed to the growing population of individuals affected by type 2 diabetes. This surge has been transformed into a substantial global concern, placing additional strain on healthcare systems already grappling with significant demands.Satyesh K. Sinha, Susanne B. Nicholasopenaire +3 more sourcesMolecular mechanisms and therapeutic targets for diabetic kidney disease [PDF]
, 2022 Diabetic kidney disease has a high global disease burden and substantially increases the risk of kidney failure and cardiovascular events. Despite treatment, there is substantial residual risk of disease progression with existing therapies.Uribarri, Jaime, Tuttle, Katherine R., Agarwal, Rajiv, Bakris, George L., Alpers, Charles E., Brosius, Frank C., Kolkhof, Peter +6 morecore +1 more sourceNew susceptibility Loci associated with kidney disease in type 1 diabetes [PDF]
, 2012 Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or kidney transplantation.Benjamin J. Keller (135013), Swan, E.J., Zerbini, G., Huang H., Savage, D.A., Groop L., He, Bing, Martin, Finian, Maxwell, Alexander P., Lefebvre P., Claes Ladenvall (135128), Isakova Tamara, Rosengård-Bärlund, Milla, Maestroni S., Cimponeriu Danut, Bing He, Ahola, A., Claes Ladenvall, Gill, G.V., Raija Lithovius (135051), Syreeni A., Ahola, Aila J., Aila J Ahola, Tregouet, David-Alexandre, Palmer, C., McKnight Amy Jayne, Emma Ahlqvist (135003), Kretzler M., Joel N Hirschhorn, Markku Lehto (135047), Kustaa Hietala (135040), Möllsten Anna, Anne-May Osterholm, Soro-Paavonen, A., McKnight, Amy Jayne, Robert L. Hanson (135175), Hosseini S. Mohsen, Hirschhorn, Joel, Österholm Anne-May, Tregouet David-Alexandre, Groop Leif, Groop, L., Kretzler, M., Taylor Andrew, Stavarachi Monica, Martin Finian, Eugen Mota, Böger C.A., Kustaa Hietala, Heikkilä O., Hanson, R.L., Maxwell, Alexander P; id_orcid, Tolonen Nina, Zerbini G., Bain, Stephen C., Kytö, Janne, He, Bin, Ahlqvist Emma, Hosseini, S.M., Wadén, Johan, Wadén J., Robert L Hanson, Cinzia Sarti, Groop Per-Henrik, Mollsten, Anna, Williams W.W., Cristian Serafinceanu, Andrew D Paterson, Mirel, Daniel B, Gu, Tianwei, Rigalleau V., Isakova T., Harjutsalo V., Pierre Lefebvre, Gordin D., Nina Tolonen, Syreeni, Anna, Bull S.B., Alhenc-Gelas, F., Lahermo Päivi, Boright, Andrew P, Raija Lithovius, Salem, Rany M., Keller, B., Candace Guiducci (135108), Mihai Ioana (135158), Soro-Paavonen Aino, Deshmukh H.A., Hans-Henrik Parving (135117), Sadlier, D., Österholm A.-M., Ahola Aila J., Saraheimo, Markku, Sarah Prior, Denise M Sadlier, Bing He (135034), Tregouet D.-A., Tolonen, Nina Emilia, Groop P.-H., Tikkanen, H., Palmer, Cameron, et al., Boright, A.P., Florez, Jose, Gianpaolo Zerbini, Aino Soro-Paavonen, Mota, E., Lahermo, Päivi, Hietala, Kustaa, Ladenvall, Claes, Swan E.J., Groop, Per-Henrik, Stavarachi M., Brismar, Kerstin, Williams, W., Thorn, L.M., Maria Mota (135162), Hirschhorn Joel N., Maestroni Silvia, Alhenc-Gelas, Francois, David A Savage, Harshal A. Deshmukh (135008), Söderlund Jenny, Osterholm, Anne-May, Paterson, Andrew D., Alexander P Maxwell, Waggott, D., Mäkinen, Ville-Petteri, Guiducci Candace, Salem R.M., Milla Rosengård-Bärlund (135064), McKay, Gareth J., Rosengård-Bärlund Milla, Savage D.A., Jaakko Tuomilehto, Rossing, P., Aino Soro-Paavonen (135070), Lithovius Raija, Maestroni, Silvia, David-Alexandre Tregouet (4350982), Silvia Maestroni, Rigalleau Vincent, Monica Stavarachi, DCCT/EDIC Research Group, Fagerholm E., Lehto M., Alexander P. Maxwell (135219), Rossing Peter, Prior S., Alhenc-Gelas F., McKnight, A.J., Danut Cimponeriu (135155), Henrik Falhammar, Hietala K., Fagerholm Emma, Markku Saraheimo, Deshmukh, H.A., François Alhenc-Gelas (135130), Möllsten A., Deshmukh Harshal A., Jenny Söderlund, Kytö Janne, Boright, Andrew P., Tarnow, Lise, Maestroni, S., Ahola, Aila, Tryggvason Karl, Rigalleau, Vincent, Jose C. Florez (114792), Ronan Roussel (101806), Elizabeth J. Swan (134990), Gordin Daniel, Prior Sarah, Williams, Winfred W., Salem, Rany M, Kretzler Matthias, Nelson R.G., Pitkäniemi J., Lund University., Mirel Daniel B., Söderlun, Jenny, Hans-Henrik Parving, Catherine Godson, Ronan Roussel, Ahlqvist E., Forsblom, C., David-Alexandre Tregouet, Heikkilä, Outi, Panduru Nicolae Mircea, Karl Tryggvason, Bull, S.B., Rossing, Peter, Cinzia Sarti (135068), Gill G.V., Keller, Benjamin J., McKnight, A., Brennan, E., Keller, B.J., Johan Wadén (135095), Bain Stephen C., Hadjadj S., Keller, Benjamin J, Hietala Kustaa, Lehto Markku, Matthias Kretzler (135179), McKnight, Amy Jayne; id_orcid, Gill, Geoffrey V, Tryggvason K., Gill Geoffrey V., Tamara Isakova, Lahermo P., Ahola, Aila J, Päivi Lahermo (95619), Guiducci C., Prior, S., Nicolae Mircea Panduru, Boright Andrew P., Serafinceanu Cristian, Andrew P Boright, Daniel B Mirel, Gu Tianwei, Godson, C., Maxwell A.P., Taylor, Andrew, Maxwell, A.P., Emma Fagerholm, Ville-Petteri Mäkinen, Roussel R., Harjutsalo, Valma, Heikki Tikkanen, Tryggvason, K., Mirel, Daniel B., Tolonen N., Carol Forsblom (134970), Sarti, C., Hosseini, S. Mohsen, Henrik Falhammar (135149), Huang, H., Saraheimo Markku, Parkkonen, Maija, Catherine Godson (93633), Soro-Paavonen, Aino, Tarnow, L., Mäkinen Ville-Petteri, Tikkanen Heikki, Lajer M., Amy Jayne McKnight (134964), Sadlier, Denise M., Lefebvre, P., Andrew Taylor, McKay Gareth J., Hosseini S.M., Sarti, Cinzia, Heikki Tikkanen (135079), Tuomilehto J., Bain, S.C., Martin, F., Mota, Maria, Fagerholm, Emma, Tianwei Gu (135152), Sadlier, Denise M, Per-Henrik Groop, Peter Rossing, Tarnow L., Maija Parkkonen, Sadlier Denise M., Per-Henrik Groop (135217), Milla Rosengård-Bärlund, Ville-Petteri Mäkinen (74272), Eugen Mota (135165), Florez J.C., Rany M. Salem (134961), Gareth J McKay, Daryl Waggott (135190), Parving H.-H., Joel N. Hirschhorn (131545), Leif Groop (12005), Ahlqvist, Emma, Syreeni Anna, Ahlqvist, Emma,, Gu, Harvest F., S. Mohsen Hosseini (135113), Anna Maestroni (135141), Pierre Lefebvre (135133), Serafinceanu C., Zerbini, Gianpaolo, Emma Fagerholm (135023), Winfred W. Williams (134981), Vincent Rigalleau, Peter Rossing (135121), Anna Möllsten (135153), Robert G. Nelson (135177), Niina Sandholm (134957), Ladenvall Claes, Palmer C., Fagerholm, E., Forsblom C., Guiducci, Candace, Deshmukh, H., Eoin P. Brennan (134968), Heikkila, O., Ahola A.J., He B., Rosengård-Bärlund M., Williams, Winfred, Gill, Geoffrey V., Lise Tarnow (135125), Anna Syreeni, Florez Jose C., Gianpaolo Zerbini (135187), Eoin P Brennan, Harshal A Deshmukh, Andrew D. Paterson (135194), Jaakko Tuomilehto (65635), McKay, Gareth J; id_orcid, Cimponeriu, Danut, Stavarachi, Monica, Mäkinen, V., Cameron Palmer, Kerstin Brismar (135185), Sandholm, Niina, Valma Harjutsalo (135029), Cameron Palmer (134993), Lefebvre, Pierre, Kyto, J., Thorn Lena M., Parving, Hans-Henrik, Prior, Sarah, Ladenvall C., Lena M. Thorn (135076), Deshmukh, Harshal A, Nelson, Robert G., Anna Syreeni (135072), Hadjadj Samy, Salem, R., Heikkilä Outi, Godson, Catherine, Maria Lajer (135188), Harvest F Gu, Pitkäniemi, Janne, Lithovius, Raija, Maija Parkkonen (135059), Isakova, T., Lehto, Markku, Waggott, Daryl, Bull Shelley B., Harjutsalo Valma, Lena M Thorn, Mirel, D.B., Aila J. Ahola (135020), Roussel Ronan, Mollsten, Anna,, Tolonen, Nina, Päivi Lahermo, Deshmukh, Harshal A., Ahlqvist, E., Hadjadj, S., Rigalleau, V., Outi Heikkilä, Danut Cimponeriu, Sadlier D.M., Swan, E., Gu H.F., Wadén Johan, Swan, Elizabeth J, Groop, Leif,, Panduru, Nicolae Mircea, Mäkinen, V.P., Hanson, Robert L., Paterson A.D., Daryl Waggott, Maria Mota, Daniel Gordin, Söderlund J., Bain S.C., Forsblom, Carol, Falhammar Henrik, Maxwell Alexander P., Rossing P., Helen M Colhoun, Marre Michel, Mota M., Pitkäniemi, Janne Mikael, Prior, Sarah Virginie, Janne Pitkäniemi, Carol Forsblom, Hirschhorn J.N., Gordin, D., Samy Hadjadj (91107), Gu T., Zerbini Gianpaolo, Sandholm, N., Sandholm N., Groop, P.H., McKnight A.J., Guiducci, C., Lithovius R., Swan, Elizabeth J., Saraheimo M., S Mohsen Hosseini, EDIC Research Group, DCCT/, Cristian Serafinceanu (135168), Florez, J.C., Michel Marre (91106), Savage, David A., Sarti C., Parving, H.H., Nelson Robert G., Tikkanen H., Elizabeth J Swan, Serafinceanu, C., Thorn, Lena M, Ioana M., Tarnow Lise, Mota, Eugen, Tikkanen, Heikki Olavi, Salem Rany M., Williams, Winfred W, Soderlund, J., Brismar K., Marre M., Karl Tryggvason (135087), Helen M. Colhoun (130220), François Alhenc-Gelas, Hanson R.L., Savage David A., Stephen C. Bain (135204), Candace Guiducci, Boright A.P., Andrew P. Boright (135000), Godson C., Groop, Per Henrik, Brismar, K., Niina Sandholm, Kytö J., Marre, Michel, Tregouet, D.A., Parkkonen M., Marre, M., Denise M. Sadlier (134987), Pitkäniemi Janne, Amy Jayne McKnight, Kerstin Brismar, Shelley B. Bull (135189), Falhammar, Henrik, Soro-Paavonen A., Brennan Eoin P., Waden, J., Palmer Cameron, Savage, David A, Maestroni, Anna, Janne Kytö, Maestroni, A., Geoffrey V Gill, Vincent Rigalleau (135135), Martin F., Brennan, Eoin P., Brismar Kerstin, Taylor, A., Colhoun H.M., Panduru N.M., Geoffrey V. Gill (135099), Ioana, Mihai, Mota Maria, Silvia Maestroni (135145), Williams Winfred W., Hirschhorn, J.N., Lefebvre Pierre, Michel Marre, Nelson, R.G., Palmer, Cameron Douglas, Palmer, Cameron D., Janne Pitkäniemi (28917), McKay G.J., Keller B.J., Taylor A., Ioana, M., Winfred W Williams, Falhammar H., Shelley B Bull, Outi Heikkilä (135037), Ladenvall, C., Gordin, Daniel, Mihai Ioana, Paterson Andrew D., Isakova, Tamara, Andrew Taylor (135110), Sarah Prior (135104), Bull, Shelley B., Colhoun Helen M., Monica Stavarachi (135172), Sarti Cinzia, Johan Wadén, Stephen C Bain, Mollsten, A., McKay, G., Mota Eugen, Lajer Maria, Lajer, Maria, Hanson Robert L., Thorn, Lena M., Benjamin J Keller, Anne-May Österholm (135054), Gu, T., Colhoun, Helen M., Cimponeriu D., David A. Savage (135199), Lajer, M., Falhammar, H., He Bing, Emma Ahlqvist, Lise Tarnow, Janne Kytö (135043), Dahlström, Emma Helena, Colhoun, H.M., Finian Martin (135209), Ioana Mihai, Serafinceanu, Cristian, Mirel D.B., Huateng Huang, Anna Möllsten, Swan Elizabeth J., Maestroni Anna, Syreeni, A., Huang, Huateng, Roussel, R., Hirschhorn, Joel N., Panduru, N.M., Samy Hadjadj, Mota E., Roussel, Ronan, Thorn L.M., Matthias Kretzler, Thorn, Lena, Finian Martin, Godson Catherine, Nina Tolonen (135081), Keller Benjamin J., Jenny Söderlund (135069), Nicolae Mircea Panduru (135181), Harvest F. Gu (135183), Alhenc-Gelas François, Sandholm Niina, Gu, H.F., Rany M Salem, Valma Harjutsalo, Florez, Jose C., Tikkanen, Heikki, Jose C Florez, He, B., Maria Lajer, Brennan E.P., Robert G Nelson, Stavarachi, M., Huang Huateng, Gordin, Ted Daniel, Daniel B. Mirel (110265), Gu Harvest F., Österholm, Anne May, Tryggvason, Karl, Tianwei Gu, Mota, M., Markku Lehto, Brennan, Eoin P, Söderlund, Jenny, Kretzler, Matthias, Mäkinen V.-P., Huateng Huang (135018), Parkkonen Maija, Boright, A., Tamara Isakova (134971), Waggott D., Leif Groop, Maestroni A., Forsblom Carol, Hadjadj, Samy, Groop, Leif, Paterson, A.D., Anna Maestroni, Daniel Gordin (135027), Gareth J. McKay (134975), Parving Hans-Henrik, Ladenvall, Claes,, Tuomilehto Jaakko, Cimponeriu, D., Waggott Daryl, Tuomilehto, Jaakko, Markku Saraheimo (135067), Sadlier, DM, McKnight, AJ, Williams, WW, Brennan, EP, Forsblom, C, Sandholm, N, Makinen, V-P, Salem, RM, McKay, GJ, Isakova, T +597 morecore +1 more sourceA novel model of reno-cardiac syndrome in the C57BL/ 6 mouse strain
BMC Nephrology, 2018 Background The end stage renal disease population has a 20 fold higher incidence of cardiovascular mortality compared to the overall population. The development of reno-cardiac syndrome in these patients will result in cardiovascular events to be the ...Julius E. Kieswich, Jianmin Chen, Samira Alliouachene, Paul W. Caton, Kieran McCafferty, Christoph Thiemermann, Muhammad M. Yaqoob +6 moredoaj +1 more source
