Results 11 to 20 of about 331,534 (287)

Exploring molecular targets in diabetic kidney disease [PDF]

Kidney Research and Clinical Practice, 2022
Diabetic kidney disease is the leading cause of end-stage kidney disease, and it remains a major challenge. Many factors, such as glomerular hyperfiltration, oxidative stress, inflammation, hypoxia, and epigenetics, are associated with the progression of
Sayako Maruno, Tetsuhiro Tanaka, Masaomi Nangaku   +2 more
doaj   +1 more source

Association between serum uric acid and renal outcome in patients with biopsy-confirmed diabetic nephropathy

Endocrine Connections, 2021
Objective: To investigate the relationship between serum uric acid (SUA) level and renal outcome in patients with type 2 diabetes mellitus (T2DM) and diabetic nephropathy (DN). Methods: A total of 393 Chinese patients with T2DM and biopsy-proven DN and
Yutong Zou, Lijun Zhao, Junlin Zhang, Yiting Wang, Yucheng Wu, Honghong Ren, Tingli Wang, Rui Zhang, Jiali Wang, Yuancheng Zhao, Chunmei Qin, Huan Xu, Lin Li, Zhonglin Chai, Mark E Cooper, Nanwei Tong, Fang Liu   +16 more
doaj   +1 more source

Addition of glomerular lesion severity improves the value of anemia status for the prediction of renal outcomes in Chinese patients with type 2 diabetes

Renal Failure, 2022
We aimed to determine the utility of biopsy data and anemia for the prediction of renal outcomes in Chinese patients with type 2 diabetes. In total, 441 Chinese patients with type 2 diabetes and biopsy-confirmed diabetic nephropathy (DN) were enrolled in
Lijun Zhao, Qianqian Han, Li Zhou, Lin Bai, Yiting Wang, Yucheng Wu, Honghong Ren, Yutong Zou, Shuangqing Li, Qiaoli Su, Huan Xu, Lin Li, Zhonglin Chai, Mark E. Cooper, Nanwei Tong, Jie Zhang, Fang Liu   +16 more
doaj   +1 more source

Managing diabetic kidney disease [PDF]

British Medical Bulletin, 2017
Diabetes mellitus (DM) is the leading cause of chronic kidney disease (CKD). This review covers the pillars of care essential for the management of diabetic kidney disease (DKD) including (1) early diagnosis, (2) improved glycaemic control, (3) treatment of hypertension, (4) identification and treatment of associated metabolic bone disease and (5 ...
Sagen, Zac-Varghese, Peter, Winocour
openaire   +2 more sources

Elevated hemoglobin glycation index identify non-diabetic individuals at increased risk of kidney dysfunction [PDF]

, 2017
Hemoglobin glycation index (HGI), calculated as the difference between the observed value of HbA1 and the predicted HbA1c based on plasma glucose concentration, is a measure of the individual tendency toward non-enzymatic hemoglobin glycation which has ...
Andreozzi F, Fiorentino TV, Marini MA, Perticone F, Sciacqua A, Sesti G, Succurro E   +6 more
core   +3 more sources

Long-term results of patients with type 2 diabetes attending a multidisciplinary diabetes kidney disease clinic

Student's Journal of Health Research Africa, 2023
Background: Diabetic and chronic kidney disease together tend to worsen the outcomes. A newer approach to treat both the comorbid disease can slow down the prognosis of both the disease leading to quality of life.
Surendra Prasad Singh
doaj   +1 more source

Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review [PDF]

, 2020
Background A growing number of epidemiological studies indicate that metabolic syndrome (MetS) and its associated features play a key role in the development of certain degenerative brain disorders, including Alzheimer’s disease and vascular dementia ...
Bell, J.D., Bell, J.D., Bligh, S.W.A., Bligh, S.W.A., Katsuno, T., Katsuno, T., Parkinson, J., Parkinson, J., Shinjyo, N., Shinjyo, N.   +9 more
core   +1 more source

A novel model of reno-cardiac syndrome in the C57BL/ 6 mouse strain

BMC Nephrology, 2018
Background The end stage renal disease population has a 20 fold higher incidence of cardiovascular mortality compared to the overall population. The development of reno-cardiac syndrome in these patients will result in cardiovascular events to be the ...
Julius E. Kieswich, Jianmin Chen, Samira Alliouachene, Paul W. Caton, Kieran McCafferty, Christoph Thiemermann, Muhammad M. Yaqoob   +6 more
doaj   +1 more source

FGF23-klotho axis as predictive factors of fractures in type 2 diabetics with early chronic kidney disease [PDF]

, 2020
Background: The aim of our study was to evaluate the relevance of FGF23-klotho axis in the predisposition for bone fractures in type 2 diabetic patients with early chronic kidney disease.
Ana Luísa Ribeiro, Ana Paula Silva, Bacchetta, Bernheim, Block, Daya, Desjardins, Ducy, Ducy, Eduarda Carias, Ferron, Filipa Mendes, Fliser, Fátima Rato, Gutiérrez, Hill, Hu, Isakova, Isakova, Jovanovich, Kazama, Lane, Lee, Levey, Manghat, Mirza, Mirza, Moayeri, Moreno, Moseley, Nélio Santos, Pedro Leão Neves, Pi, Pinkau, Qu, Quarles, Ray, Sanches, Sellmeyer, Shimada, Silva, Silva, Silva, Sitara, Stubbs, Titan, Torres, Urakawa, Wallace, Wang, Wolf, Yilmaz, Zimering   +52 more
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Is Bariatric Surgery an Effective Treatment for Type II Diabetic Kidney Disease? [PDF]

, 2015
Type II diabetic kidney disease is devastating to patients and society alike. This review will evaluate bariatric surgery as a treatment for diabetic kidney disease primarily through its ability to induce and maintain regression of type II diabetes.
Friedman, Allon N., Wolfe, Bruce
core   +1 more source