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Risk Factors of Diabetic Nephropathy Among A Group of Iraqi Children with Type 1 Diabetes Mellitus

The Iraqi Journal of Medical Sciences, 2023
Background: Diabetic nephropathy is the major cause of end-stage kidney disease in patients with diabetes mellitus. Objective: To identify risk factors for occurrence of Diabetic nephropathy among group of Iraqi children with type 1 diabetes ...
Mohammed Hammoud, Faris Alawsi, Shatha Ali, Rayah Baban   +3 more
doaj   +9 more sources

Platelet Indices as Predictors of Diabetic Kidney Disease in Type 2 Diabetes Mellitus [PDF]

International Journal of Medical Arts, 2023
Background: Type 2 diabetes (T2D) is characterized as a complicated and varied group of metabolic conditions. The disorder's defining feature is increased blood sugar level brought on by a malfunction in insulin action and/or secretion.Aim of the Work ...
Ahmed Elsayed, Mahmoud Bazeed, Youssef Nassar, Nesreen Hamdy   +3 more
doaj   +1 more source

Bidirectional association between depression and diabetic nephropathy by meta-analysis

PLoS ONE, 2022
Background Studies suggested that the association between depression and diabetic nephropathy may be bi-directional, but this hypothesis remains investigating.
Tingting Fang, Qiuling Zhang, Zhiguo Wang, Jun-Ping Liu   +3 more
doaj   +2 more sources

MicroRNA 146a is associated with diabetic complications in type 1 diabetic patients from the EURODIAB PCS

Journal of Translational Medicine, 2021
Background MicroRNA-146a-5p (miR-146a-5p) is a key regulator of inflammatory processes. Expression of miR-146a-5p is altered in target organs of diabetic complications and deficiency of miR-146a-5p has been implicated in their pathogenesis.
Federica Barutta, Beatrice Corbetta, Stefania Bellini, Simonetta Guarrera, Giuseppe Matullo, Michela Scandella, Casper Schalkwijk, Coen D. Stehouwer, Nish Chaturvedi, Sabita S. Soedamah-Muthu, Marilena Durazzo, Gabriella Gruden   +11 more
doaj   +1 more source

Natural coumarins: Preclinical evidence-based potential candidates to alleviate diabetic nephropathy

Phytomedicine Plus, 2022
Background: Cis-o-hydroxycinnamic acid lactones, referred to as natural coumarin, have a basic skeleton of benzopyranone in their structure. The natural coumarins are typically found abundantly in roots, rhizomes, bark, and leaves of the plant belonging ...
Sitara Ghosh, Ankana Ghosh, Ashitha Rajanan, Amal Jyothy Suresh, Pratiksha Sharadrao Raut, Sourav Kundu, Bidya Dhar Sahu   +6 more
doaj   +1 more source

Excessive Activation of Notch Signaling in Macrophages Promote Kidney Inflammation, Fibrosis, and Necroptosis

Frontiers in Immunology, 2022
Diabetic nephropathy (DN) is one of the main causes of end-stage renal disease (ESRD). Existing treatments cannot control the progression of diabetic nephropathy very well. In diabetic nephropathy, Many monocytes and macrophages infiltrate kidney tissue.
Tiankui Ma, Xin Li, Xin Li, Yonghong Zhu, Shufan Yu, Tianyan Liu, Xiaodan Zhang, Dong Chen, Shuyan Du, Tong Chen, Shuo Chen, Yanyan Xu, Yanyan Xu, Qiuling Fan   +13 more
doaj   +1 more source

Diabetic nephropathy ameliorated in patients with normal home blood pressure compared to those with isolated high home systolic blood pressure: A 5-year prospective cohort study among patients with type 2 diabetes mellitus

Diabetes & Vascular Disease Research, 2022
Background: Using normal home blood pressure (home BP) as a reference, isolated high home systolic blood pressure (IH-home SBP) increases the risk of diabetic nephropathy.
Nobuko Kitagawa, Emi Ushigome, Noriyuki Kitagawa, Hidetaka Ushigome, Isao Yokota, Naoko Nakanishi, Masahide Hamaguchi, Mai Asano, Masahiro Yamazaki, Michiaki Fukui   +9 more
doaj   +1 more source

The association and prediction value of acylcarnitine on diabetic nephropathy in Chinese patients with type 2 diabetes mellitus

Diabetology & Metabolic Syndrome, 2023
Background Acylcarnitines play a role in type 2 diabetes mellitus (T2DM), but the relationship between acylcarnitine and diabetic nephropathy was unclear.
Xuerui Li, Yuyang Miao, Zhongze Fang, Qiang Zhang   +3 more
doaj   +1 more source

The relationship between melatonin level and antioxidant enzymes in diabetic patients with and without nephropathy

Baghdad Journal of Biochemistry and Applied Biological Sciences, 2023
Background and objective: Diabetes is the most common cause of chronic renal disease globally. Diabetic nephropathy (DN) is one of the most serious consequences of type 2 diabetes.
Asaad Al-Khafaji, Seyed M. Mir, Fatemeh Mohammadzadeh, Maryam Abolghasemi, Mahmoud H. Hadwan   +4 more
doaj   +1 more source

Hyperglycemia and Hyperlipidemia Act Synergistically to Induce Renal Disease in LDL Receptor-Deficient BALB Mice [PDF]

, 2004
Diabetic nephropathy is the leading cause of end-stage renal disease in Western countries, but only a portion of diabetic patients develop diabetic nephropathy.
Alpers, Charles E., Hudkins, Kelly L., Kirk, Elizabeth, LeBoeuf, Renée C., Mühlfeld, Anja S., Segerer, Stephan, Spencer, Min W.   +6 more
core   +1 more source