Results 21 to 30 of about 193,013 (355)

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source

High glucose up-regulates ENaC and SGK1 expression in HCD-cells [PDF]

, 2006
Background/Aim: Diabetic nephropathy is associated with progressive renal damage, leading to impaired function and end-stage renal failure. Secondary hypertension stems from a deranged ability of cells within the kidney to resolve and appropriately ...
Bell LM, Bhargava A, Bland R, Christensen O, Claire Hills, Demerdash TM, Di Paolo S, Hoffman BB, Hong-Long JI, Jeanette Bennett, Khan ZA, Lang F, Lee CT, Lindschau C, Loffing J, Marshall SM, Paul Squires, Pierre Ronco, Prie D, Ricci C, Rosemary Bland, Rossier, Satlin LM, Sharma K, Symonian M, Urbach V, Waldegger S, Wang J, Weigert C, Whiteside CI, Yung S   +30 more
core   +1 more source

Long-term glycemic variability and risk of adverse outcomes: a systematic review and meta-analysis [PDF]

, 2015
OBJECTIVE: Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular ...
Catherine Gorst, Cavalot, Chun Shing Kwok, Evangelos Kontopantelis, Foo, Grant Heatlie, Hermann, Iain Buchan, Kontopantelis, Lin, Maciejewski, Mamas A. Mamas, Martin K. Rutter, Phyo K. Myint, Raman, Saadia Aslam, Skriver, Sperrin, Yoon Loke   +18 more
core   +1 more source

Diabetic Nephropathy without Diabetes [PDF]

Journal of Clinical Medicine, 2015
Diabetic nephropathy without diabetes (DNND), previously known as idiopathic nodular glomerulosclerosis, is an uncommon entity and thus rarely suspected; diagnosis is histological once diabetes is discarded. In this study we describe two new cases of DNND and review the literature. We analyzed all the individualized data of previous publications except
López-Revuelta, Katia, Abreu, Angel A Méndez, Gerrero-Márquez, Carmen, Stanescu, Ramona-Ionela, Marín, Maria Isabel Martínez, Fernández, Elia Pérez   +5 more
openaire   +3 more sources

Sex-specific-differences in cardiovascular risk in type-1-diabetes : a cross sectional study [PDF]

, 2013
Background: Little is known about the impact of sex-specific differences in the management of type 1 diabetes (T1DM). Thus, we evaluated the influence of gender on risk factors, complications, clinical care and adherence in patients with T1DM.
Hinstersteiner, Juliane, Johnson, Julienne, Kamyar, Majid Reza, Kautzky, Alexander, Kautzky-Willer, Alexandra, Lemmens-Gruber, Rosa, Saukel, Johannes, Stich, Kathrin   +7 more
core   +1 more source

Managing diabetic nephropathy [PDF]

Clinical Medicine, 2010
The earliest sign of DN is the development of microalbuminuria which is associated with a significant risk of both progressive renal failure and premature death from cardiovascular disease. Optimal glycaemic and BP control, including the use of RAAS blocking drugs, can prevent, slow and even reverse the processes causing DN.
Shields, Joanne, Maxwell, Alexander P
openaire   +2 more sources

Awareness of diabetic nephropathy in patients with type 2 diabetes mellitus: the Indian scenario [PDF]

Journal of Nephropharmacology, 2018
Introduction: Diabetic nephropathy is an important complication of diabetes mellitus leading to significant morbidity and mortality. Objectives: To study the awareness of diabetic nephropathy in patients with type 2 diabetes mellitus (T2DM) and the ...
Chirag Bansal, Reshma Kaushik, Rajeev Mohan Kaushik   +2 more
doaj  

Pharmacologic approaches against advanced glycation end products (ages) in diabetic cardiovascular disease [PDF]

, 2015
Advanced Glycation End-Products (AGEs) are signaling proteins associated to several vascular and neurological complications in diabetic and non-diabetic patients.
Avtaar Singh, Sanjeet Singh, Chello, Massimo, DI DOMENICO, Fabio, Nappi, Francesco, Nenna, Antonio, Spadaccio, Cristiano, Sutherland, Fraser W   +6 more
core   +2 more sources

Silent diabetic nephropathy [PDF]

Kidney International, 2016
Moderately increased albuminuria is widely accepted as the first clinical sign of diabetic nephropathy. However, previous morphometric studies and the autopsy study by Klessens et al. have clearly demonstrated that by the time moderately increased albuminuria is evident, the kidneys in some diabetic patients have already undergone glomerular and ...
Samar M, Said, Samih H, Nasr
openaire   +2 more sources

PENURUNAN BILIRUBIN MENINGKATKAN OKSIDASI LIPOPROTEIN A PADA NEFROPATI DIABETIK

JKS (Jurnal Kedokteran Syiah Kuala), 2017
. Diabetic nephropathy is the most common complication of microvascular disease due to diabetes and the third leading cause of renal failure to the end stage.
Meutia Atika Faradilla, Yahwardiah Siregar, Darwin Dalimunthe   +2 more
doaj   +1 more source