Results 21 to 30 of about 112,312 (307)

The role of TGF-β and epithelial-to mesenchymal transition in diabetic nephropathy [PDF]

, 2011
Transforming Growth Factor-beta (TGF-β) is a pro-sclerotic cytokine widely associated with the development of fibrosis in diabetic nephropathy. Central to the underlying pathology of tubulointerstitial fibrosis is epithelial-to-mesenchymal transition ...
Hills, Claire E., Paul E. Squires, Claire E. Hills, Squires, Paul E.   +3 more
core   +1 more source

Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis [PDF]

, 2008
Background: Diabetic nephropathy (DN) is a complex and chronic metabolic disease that evolves into a progressive fibrosing renal disorder. Effective transcriptomic profiling of slowly evolving disease processes such as DN can be problematic.
Seifert, Martin, Hermann-Josef Gröne, Gröne, H J, Nelson, P. J., Felix Eichinger, Moll, Anton G., Kiss, Eva, Lindenmeyer, M T, Grone, E., Kiss, E, Nelson, P J, Gröne, Elisabeth, Anton G Moll, Schmid, H., Grone, H. J., Matthias Kretzler, Lindenmeyer, Maja T., Cohen, C D, Alexander Hahn, Moll, A G, Gröne, E, Holger Schmid, Hahn, A, Eichinger, F, Werner, T, Eichinger, F., Hahn, Alexander, Clemens D Cohen, Schmid, H, Martin Seifert, Kretzler, M., Werner, Thomas, Hahn, A., Seifert, M., Lindenmeyer, M. T., Kiss, E., Eichinger, Felix, Nelson, Peter J., Seifert, M, Kretzler, Matthias, Maja T Lindenmeyer, Cohen, Clemens D., Kretzler, M, Elisabeth Gröne, Gröne, Hermann-Josef, Peter J Nelson, Schmid, Holger, Eva Kiss, Cohen, C. D., Werner, T., Thomas Werner   +50 more
core   +1 more source

A Case of Rapidly Progressive Diabetic Nephropathy Induced by Osimertinib

Case Reports in Nephrology and Dialysis, 2023
The number of patients with diabetic nephropathy is increasing worldwide and it is important to understand the underlying pathological mechanisms of the disease.
Kazunori Karasawa, Ken-ichi Akiyama, Taro Akihisa, Yoei Miyabe, Kosaku Nitta, Junichi Hoshino   +5 more
doaj   +1 more source

Diabetic nephropathy [PDF]

Diabetology & Metabolic Syndrome, 2009
Diabetic nephropathy is the leading cause of chronic renal disease and a major cause of cardiovascular mortality. Diabetic nephropathy has been categorized into stages: microalbuminuria and macroalbuminuria. The cut-off values of micro- and macroalbuminuria are arbitrary and their values have been questioned.
Zelmanovitz Themis, Gerchman Fernando, Balthazar Amely PS, Thomazelli Fúlvio CS, Matos Jorge D, Canani Luís H   +5 more
openaire   +3 more sources

Hyperglycemia and Hyperlipidemia Act Synergistically to Induce Renal Disease in LDL Receptor-Deficient BALB Mice [PDF]

, 2004
Diabetic nephropathy is the leading cause of end-stage renal disease in Western countries, but only a portion of diabetic patients develop diabetic nephropathy.
Segerer, Stephan, Spencer, Min W., Mühlfeld, Anja S., Alpers, Charles E., Hudkins, Kelly L., LeBoeuf, Renée C., Kirk, Elizabeth, Mühlfeld, Anja Susanne   +7 more
core   +1 more source

Awareness of diabetic nephropathy in patients with type 2 diabetes mellitus: the Indian scenario [PDF]

Journal of Nephropharmacology, 2018
Introduction: Diabetic nephropathy is an important complication of diabetes mellitus leading to significant morbidity and mortality. Objectives: To study the awareness of diabetic nephropathy in patients with type 2 diabetes mellitus (T2DM) and the ...
Chirag Bansal, Reshma Kaushik, Rajeev Mohan Kaushik   +2 more
doaj  

Multicentric validation of proteomic biomarkers in urine specific for diabetic nephropathy [PDF]

, 2010
Background: Urine proteome analysis is rapidly emerging as a tool for diagnosis and prognosis in disease states. For diagnosis of diabetic nephropathy (DN), urinary proteome analysis was successfully applied in a pilot study.
Navis, G.J., Zürbig, P., Fuchs, S., Winklhofer-Roob, B.M., Cerna Marie, Rossing Peter, Federici, M., Bakker Stephan J. L., Fischer Christine, Bakker, Stephan J. L.; id_orcid, Fuchs Sebastian, Zurbig, Petra, Rychlik, Ivan, Rychlík, I., Karel Medek, Navis, Gerjan J., Fischer, Christine, Cerna, Marie, Rossing, K., Gerjan J. Navis, Mischak Harald, Sebastian Fuchs, Stephan J L Bakker, Bilo Henk J. G., Mischak, H., Kasper Rossing, Medek, K., Rossing Kasper, PREDICTIONS Group, Bilo, H.J.G., Medek, Karel, null null, Fischer, C., Johannes M. Roob, Roob Johannes M., Alkhalaf, A., Mischak, Harald, Cerna, M., Janssen, Bart, Fuchs, Sebastian, Bakker, S.J.L., Johannes M Roob, Alaa Alkhalaf, Janssen, B., Bakker, Stephan J. L., Ivan Rychlík, Brigitte M. Winklhofer-Roob, Tiran, Beate, Rychlík Ivan, Roob, Johannes M., Zürbig Petra, Sourij, H., Tiran Beate, Bilo, Henk J. G., Rossing, Peter, Sourij Harald, Winklhofer-Roob, Brigitte M., Navis Gerjan J., Gerjan J Navis, Marie Cerna, Alkhalaf, Alaa, Henk J G Bilo, Christine Fischer, Petra Zürbig, Janssen Bart, Peter Rossing, Bart Janssen, Henk J. G. Bilo, Alkhalaf Alaa, Medek Karel, Harald Mischak, Stephan J. L. Bakker, Tiran, B., Rossing, P., Brigitte M Winklhofer-Roob, Sourij, Harald, Rossing, Kasper, Roob, J.M., Harald Sourij, Beate Tiran, Winklhofer-Roob Brigitte M.   +80 more
core   +1 more source

Association of ACE gene polymorphism and diabetic nephropathy? [PDF]

, 1995
Association of ACE gene polymorphism and diabetic nephropathy. In patients with type 1 diabetes an association has been found between an insertion/deletion (I/D) polymorphism in the gene for angiotensin I converting enzyme and the presence of diabetic ...
Ritz, Eberhard, Schöne, Nina, Schmidt, Susanne, The Diabetic Nephropathy Study Group,   +3 more
core   +1 more source

PENURUNAN BILIRUBIN MENINGKATKAN OKSIDASI LIPOPROTEIN A PADA NEFROPATI DIABETIK

JKS (Jurnal Kedokteran Syiah Kuala), 2017
. Diabetic nephropathy is the most common complication of microvascular disease due to diabetes and the third leading cause of renal failure to the end stage.
Meutia Atika Faradilla, Yahwardiah Siregar, Darwin Dalimunthe   +2 more
doaj   +1 more source

Pathophysiology of mesangial expansion in diabetic nephropathy: mesangial structure, glomerular biomechanics, and biochemical signaling and regulation

Journal of Biological Engineering, 2022
Diabetic nephropathy, a kidney complication arising from diabetes, is the leading cause of death in diabetic patients. Unabated, the growing epidemic of diabetes is increasing instances of diabetic nephropathy.
Haryana Y. Thomas, Ashlee N. Ford Versypt   +1 more
doaj   +1 more source