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Background. Although the rate of diabetic nephropathy which is the leading cause of end-stage renal disease (ESRD) continues to rise, there is limited information about the problem.
Sewnet Adem Kebede +4 more
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The Role of Diacylglycerol Kinase in the Amelioration of Diabetic Nephropathy
The drastic increase in the number of patients with diabetes and its complications is a global issue. Diabetic nephropathy, the leading cause of chronic kidney disease, significantly affects patients’ quality of life and medical expenses.
Daiki Hayashi, Yasuhito Shirai
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Functional expression of TRPV4 channels in human collecting duct cells : implications for secondary hypertension in diabetic nephropathy [PDF]
Background. The Vanilloid subfamily of transient receptor potential (TRPV) ion channels has been widely implicated in detecting osmotic and mechanical stress.
Hills, Claire E. +2 more
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Managing diabetic nephropathy [PDF]
The earliest sign of DN is the development of microalbuminuria which is associated with a significant risk of both progressive renal failure and premature death from cardiovascular disease. Optimal glycaemic and BP control, including the use of RAAS blocking drugs, can prevent, slow and even reverse the processes causing DN.
Shields, Joanne, Maxwell, Alexander P
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Mechanism of hypertension in diabetic nephropathy [PDF]
High prevalence of hypertension is observed in diabetic patients of both the types. Diabetic nephropathy is one of the major reason for high morbidity, mortality and financial burden in such hypertensive diabetic patients.
Nazar Chaudhary Muhammad Junaid
core
Type 2 diabetes mellitus is the most common cause of diabetes, consist from about 85% of cases. Diabetic nephropathy is a complication of diabetes mellitus in the kidneys which can end up as kidney failure.
Jusni Ekasari Pelu +6 more
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Effects of N-acetyl cysteine on serum lipoprotein (a) and proteinuria in type 2 diabetic patients [PDF]
Background: About 30-40 of diabetic patients who developed nephropathy have lipoprotein disorders, especially lipoprotein a Lp(a), which is related to atherosclerosis.
Forouzan Ganji +4 more
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Effects of physical activity on the development and progression of microvascular complications in type 1 diabetes : retrospective analysis of the DCCT study [PDF]
Background: To examine the effects of physical activity on the development and progression of microvascular complications in patients with type 1 diabetes. Methods: A retrospective analysis of data from the Diabetes Control and Complications trial was
Krishnarajah Nirantharakumar +10 more
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Ludwig, Merker +4 more
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Diabetic nephropathy is the most common cause of end-stage renal disease (ESRD) and accounts for 35% of the ESRD population in the United States. It results in considerable morbidity, mortality, and expense. The average cost of managing one diabetic patient with ESRD is approximately $50,000 a year.
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