Results 61 to 70 of about 463,148 (204)

Fractalkine in type 2 Egyptian diabetics with and without nephropathy

The Egyptian Journal of Internal Medicine, 2013
Background Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both.
Ebtissam Zakaria, Hoda Al-Rawi, Nashwa S. Ghanem, Naglaa M. Elsayed, Laila A. Rashed   +4 more
doaj   +1 more source

Smoking and diabetic nephropathy: An updated systematic review and meta‐analysis

Journal of Diabetes Investigation
Objectives Several studies have reported the potential association between smoking and diabetic nephropathy. However, the studies of non‐significant association results were against the association between smoking and diabetic nephropathy. Therefore, the
Haihui Zhu, Liang Li, Songchun Liu, Jing Li   +3 more
doaj   +1 more source

Genetic influences of the intercellular adhesion molecule 1 (ICAM-1) gene polymorphisms in development of Type 1 diabetes and diabetic nephropathy

, 2006
AIM: The intercellular adhesion molecule-1 (ICAM-1) gene is located on chromosome 19p13, which is linked to Type 1 diabetes (T1D). ICAM-1 expression is related to development of T1D and diabetic nephropathy. The present study aims to evaluate the genetic
Prázny, M, Efendic, S, Ma, J, Gu, HF, Brismar, K, Dahlquist, G, Moellsten, A, Möllsten, A,, Falhammar, H, Gu, H F, Brismar, K,, Falhammar, H,, Dahlquist, G,   +12 more
core   +1 more source

Erk5 Mediates TGFβ1-induced Loss of Phenotype and Function in Human Podocytes [PDF]

, 2014
Diabetic nephropathy is one of the most common causes of renal impairment. Podocytes are specialised cells integral to normal kidney physiology, however in diabetes injury occurs leading to compromised function which is a critical factor in the ...
Irbaz I. Badshah, Irbaz Isaac Badshah, Deborah L. Baines, Dockrell, ME, Baines, DL, Mark Edward Dockrell, Mark E. Dockrell, Deborah L Baines, Badshah, II   +8 more
core   +1 more source

The association between diabetic nephropathy and polymorphisms in PPARγ Pro12Ala and CCR5δ 32 genes in type 2 diabetes

The Egyptian Journal of Internal Medicine, 2013
Background Diabetic nephropathy is one of the debilitating complications of type 2 diabetes and the leading cause for end-stage renal disease requiring renal replacement therapy.
Asmaa I. Ahmed, Noha A. Osman, Mohamed M. NasrAllah, Manal M. Kamal   +3 more
doaj   +1 more source

Diabetic nephropathy in children [PDF]

Nephrology Dialysis Transplantation, 2001
It is estimated that among 100 million European children aged 0–14 years, some 10 000 will develop insulin-dependent diabetes mellitus (IDDM) each year. Within a subset of 10–30% of IDDM patients who will ultimately develop diabetic nephropathy (DN), the earliest stages of disease can be detected within the first 4–5 years after diagnosis w1–3x.
openaire   +2 more sources

miR-205-5p ameliorates podocyte injury in diabetic nephropathy by targeting vascular endothelial growth factor A

Science Progress
Objective This work aims to elucidate the effect and the regulatory mechanisms of miR-205-5p on podocyte injury and oxidative stress in diabetic nephropathy. Methods A mouse model of diabetic nephropathy was established.
Yingdan Zhao, Yunhai Tang, Qingqing Wang, Xia Wu, Zifan He, Yayun He, Zhihuan Tang   +6 more
doaj   +1 more source

Type-2 Diabetic Nephropathy in Japan : From Bench to Bedside /

, 2001
Type-2 diabetic nephropathy is one of the major long-term microvascular complications occurring in nearly 40% of diabetic patients in Japan. The purpose of this book is to review recent work on the genetic background, pathogenesis and treatment of this ...
Tomino, Y.
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Diabetic nephropathy – complications and treatment

, 2014
Andy KH Lim1–3 1Department of Nephrology, Monash Medical Center, Monash Health, 2Department of General Medicine, Dandenong Hospital, Monash Health, 3Department of Medicine, Monash University, Clayton, VIC, Australia Abstract: Diabetic nephropathy ...
Lim AK
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Growth factors in the pathogenesis of diabetic nephropathy

, 2011
Despite the growing toll of diabetic nephropathy on public health [1], the current armamentarium for treatment and prevention of the disease remains limited to the blocking of the renin-angiotensin-aldosterone system (RAAS) and the control of ...
Khoury C.C., Ziyadeh F.N.
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