Results 61 to 70 of about 112,312 (307)

Recent Progress in Genetics and Epigenetics Research on Diabetic Nephropathy in Malaysia

open access: yesJournal of Diabetes Research, 2023
Diabetic nephropathy is a multifactorial disease. Gene susceptibility, as well as environmental exposure, plays an important role in disease progression.
Norhashimah Abu Seman   +1 more
doaj   +1 more source

Managing diabetic nephropathy [PDF]

open access: yesClinical Medicine, 2010
The earliest sign of DN is the development of microalbuminuria which is associated with a significant risk of both progressive renal failure and premature death from cardiovascular disease. Optimal glycaemic and BP control, including the use of RAAS blocking drugs, can prevent, slow and even reverse the processes causing DN.
Shields, Joanne, Maxwell, Alexander P
openaire   +2 more sources

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

Association Between Abnormal Glycemic Phenotypes and Microvascular Complications of Type 2 Diabetes Mellitus Outpatients in China

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2020
Guangxu Liu,1,2 Jingtao Dou,3,4 Deqiang Zheng,1,2 Jie Zhang,1,2 Meiping Wang,1,2 Wei Li,1,2 Jing Wen,1,2 Juming Lu,3 Linong Ji,5 Yan He1,2 1Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing, People&
Liu G   +9 more
doaj  

Glycopatterns of Urinary Protein as New Potential Diagnosis Indicators for Diabetic Nephropathy

open access: yesJournal of Diabetes Research, 2017
Diabetic nephropathy is a major cause of chronic kidney disease and end-stage kidney disease. However, so little is known about alterations of the glycopatterns in urine with the development of diabetic nephropathy.
Hanyu Zhu   +13 more
doaj   +1 more source

Growth factors in the pathogenesis of diabetic nephropathy [PDF]

open access: yes, 2011
Despite the growing toll of diabetic nephropathy on public health [1], the current armamentarium for treatment and prevention of the disease remains limited to the blocking of the renin-angiotensin-aldosterone system (RAAS) and the control of ...
Khoury C.C., Ziyadeh F.N.
core  

Underuse of Ace Inhibitors and Angiotensin Ii Receptor Blockers among Patients with Diabetic Nephropathy in Taiwan [PDF]

open access: yes, 2012
Objectives: National guidelines recommend angiotensin- converting enzyme inhibitors (ACE15) or angiotensin receptor blockers (ARBs) therapy for diabetic patients with hypertension and/or proteinuria to hinder renal disease progression. However, little is
YEH, HSENG-LONG;HUANG, LOREEN LI-YING;SU, SYI;YANG, MING-CHIN   +1 more
core   +1 more source

Sestrin2 Signaling Pathway Regulates Podocyte Biology and Protects against Diabetic Nephropathy

open access: yesJournal of Diabetes Research, 2023
Sestrin2 regulates cell homeostasis and is an upstream signaling molecule for several signaling pathways. Sestrin2 leads to AMP-activated protein kinase- (AMPK-) and GTPase-activating protein activity toward Rags (GATOR) 1-mediated inhibition of ...
Moein Ala
doaj   +1 more source

Strategies for inducing diabetes in laboratory animals: Advances from chemical, surgical, immunologic, dietary, and genetic approaches

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji   +2 more
wiley   +1 more source

Mechanism of hypertension in diabetic nephropathy [PDF]

open access: yes, 2014
High prevalence of hypertension is observed in diabetic patients of both the types. Diabetic nephropathy is one of the major reason for high morbidity, mortality and financial burden in such hypertensive diabetic patients.
Nazar Chaudhary Muhammad Junaid
core  

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