Results 71 to 80 of about 463,148 (204)

Immunoglobulin heavy constant gamma 1 silencing decreases tonicity‐responsive enhancer‐binding protein expression to alleviate diabetic nephropathy

Journal of Diabetes Investigation
Aims/Introduction The molecular mechanisms of diabetic nephropathy (DN) are poorly identified. However, the advantage of an increasing amount on microarray data of diabetic nephropathy intrigued us to explore the mechanisms based on bioinformatics ...
Qibo Hu, Qingxiao Yang, Hang Gao, Jing Tian, Guanghua Che   +4 more
doaj   +1 more source

A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes.

PLoS ONE, 2018
To explore novel genetic loci for diabetic nephropathy, we performed genome-wide association studies (GWAS) for diabetic nephropathy in Japanese patients with type 2 diabetes. We analyzed the association of 5,768,242 single nucleotide polymorphisms (SNPs)
Makiko Taira, Minako Imamura, Atsushi Takahashi, Yoichiro Kamatani, Toshimasa Yamauchi, Shin-Ichi Araki, Nobue Tanaka, Natalie R van Zuydam, Emma Ahlqvist, Masao Toyoda, Tomoya Umezono, Koichi Kawai, Masahito Imanishi, Hirotaka Watada, Daisuke Suzuki, Hiroshi Maegawa, Tetsuya Babazono, Kohei Kaku, Ryuzo Kawamori, SUMMIT Consortium, Leif C Groop, Mark I McCarthy, Takashi Kadowaki, Shiro Maeda   +23 more
doaj   +1 more source

Nondiabetic kidney diseases in type 2 diabetic patients

Kidney Research and Clinical Practice, 2013
Background: The aim of this study was to evaluate the clinical characteristics of nondiabetic nephropathy in type 2 diabetes mellitus patients and to find a clinical significance of renal biopsy and immunosuppressive treatment in such a patient. Methods:
Ye Jin Kim, Yoo Hyung Kim, Ki Dae Kim, Kang Ryun Moon, Jae Ho Park, Bo Mi Park, Hyewon Ryu, Dae Eun Choi, Ki Ryang Na, Kwang Sun Suh, Kang Wook Lee, Young Tai Shin   +11 more
doaj   +1 more source

Therapeutic approaches to slowing the progression of diabetic nephropathy – is less best?

, 2013
Objective: Angiotensin II receptor blockers (ARBs) and angiotensin-converting enzyme (ACE) inhibitors are known to reduce proteinuria and have been the first-line agents in the management of diabetic nephropathy for the past 20 years.
Chelsea Mannebach, Eva Vivian
core   +1 more source

Age at onset of type 1 diabetes between puberty and 30 years old is associated with increased diabetic nephropathy risk

Scientific Reports
Diabetic nephropathy is a critical complication of patients with type 1 diabetes, while epidemiological studies were scarce among Asian countries.
Yen-Bo Lin, Taiwan Diabetes Registry Study Group, Tien-Jyun Chang   +2 more
doaj   +1 more source

Pathogenesis and Treatment of Chronic Kidney Disease: A Review of Our Recent Basic and Clinical Data

Kidney & Blood Pressure Research, 2014
Chronic kidney disease (CKD) is a worldwide public health problem that affects millions of people from all racial and ethnic groups. At end of 2013, over 300,000 Japanese patients had maintenance dialysis therapy (JSDT). In Japan, the major causes of end
Yasuhiko Tomino
doaj   +1 more source

Análise da variabilidade da frequência cardíaca em pacientes diabéticos com e sem nefropatia [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2014.INTRODUÇÃO: O número de indivíduos com Diabetes Mellitus (DM) vem aumentando de forma ...
Wayhs, Cláudio
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Prevalence and risk factors of diabetic nephropathy among type 2 diabetes patients in family medicine clinic AFHSR Khamis Mushait

Journal of Family Medicine and Primary Care
Background: Diabetic nephropathy is a frequent complication of diabetes mellitus, affecting a considerable proportion of patients. Despite confirmed rising prevalence worldwide, little is known about its epidemiology in Saudi Arabia or its connection to ...
Saeed Mohammed Al-Shahrani, Bandar Mohammed Shaher, Yahya Mohammed Alragea, Fatima Mohammad Ali Alqahtani, Amjad Saeed Mansour Binghamiah, Mansour Ali Mansour Alqahtani, Saad Abdullah Mufrrih   +6 more
doaj   +1 more source

Eucommia bark (Du-Zhong) improves diabetic nephropathy without altering blood glucose in type 1-like diabetic rats

, 2016
Ho-Shan Niu,1 I-Min Liu,2 Chiang-Shan Niu,1 Po-Ming Ku,3,4 Chao-Tien Hsu,5 Juei-Tang Cheng4,6 1Department of Nursing, Tzu Chi University of Science and Technology, Hualien City, 2Department of Pharmacy & Graduate Institute of Pharmaceutical ...
Hsu CT, Liu IM, Niu CS, Ku PM, Niu HS, Cheng JT   +5 more
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Aldosterone: Implications in Diabetic Nephropathy

, 2021
: Objective: The focus of this review is to summarize the recent advancement to understand the molecular pathogenesis of diabetic nephropathy (DN).
Hussain, Syed Saad, Razzak, Zaid Abdul, Rehman, Fasiha Abdul   +2 more
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