Results 71 to 80 of about 112,312 (307)

Diabetic alteration versus postnatal maturation of rat kidney glycoconjugates — comparative detection by lectin probes [PDF]

, 2013
A panel of ten lectins with different carbohydrate specificities, including three original lectin preparations (MPFA, LABA, and LVA), was used for the investigation of rat kidney glycoconjugate remodeling during postnatal morphogenesis, and the findings ...
Ambarova, Natalya; Department of Histology and Embryology, Lviv National, Medical University, Lviv, Ukraine, Lutsyk, Alexander; Department of Histology and Embryology, Lviv National, Medical University, Lviv, Ukraine, Antonyuk, Volodymyr; Department of Histology and Embryology, Lviv National, Medical University, Lviv, Ukraine; Institute of Cell Biology, National Academy of Sciences of Ukraine, Lviv, Ukraine   +2 more
core   +2 more sources

Redox Signaling in Diabetic Nephropathy: Hypertrophy versus Death Choices in Mesangial Cells and Podocytes

Mediators of Inflammation, 2015
This review emphasizes the role of oxidative stress in diabetic nephropathy, acting as trigger, modulator, and linker within the complex network of pathologic events.
Gina Manda, Alexandru-Ionel Checherita, Maria Victoria Comanescu, Mihail Eugen Hinescu   +3 more
doaj   +1 more source

Vasopressin and diabetic nephropathy [PDF]

Current Opinion in Nephrology and Hypertension, 2017
The prevalence of diabetic kidney disease (DKD) is increasing worldwide. Despite major therapeutic advances in the last decades in DKD, the current standard of care let many people progress to severe stages. Vasopressin secretion is increased in diabetes, and its potential role in the onset and progression of DKD is being re-investigated.Recently ...
Roussel, Ronan, Velho, Gilberto, Bankir, Lise   +2 more
openaire   +2 more sources

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

Annals of Neurology, EarlyView.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff, David L. Bennett, Troels S. Jensen, Eva L. Feldman   +3 more
wiley   +1 more source

Serum levels of advanced glycation endproducts and other markers of protein damage in early diabetic nephropathy in type 1 diabetes [PDF]

, 2012
Objective To determine the role of markers of plasma protein damage by glycation, oxidation and nitration in microalbuminuria onset or subsequent decline of glomerular filtration rate (termed “early GFR decline”) in patients with type 1 diabetes ...
Weston Andrew, Rabbani, N, Warram, James, Paul Thornalley, Perkins, BA, Naila Rabbani, Monika Niewczas, Thornalley, P, Thornalley, Paul J., Krolewski, AS, Rabbani, Naila, Adaikalakoteswari Antonysunil, Perkins Bruce A., Bruce A Perkins, Perkins, Bruce A., Weston, A, Thornalley Paul, Rabbani Naila, Krolewski, Andrzej S., Niewczas, M, Antonysunil Adaikalakoteswari, Adaikalakoteswari, A, Weston, Andrew J., Linda H Ficociello, Ficociello, LH, Ficociello Linda H., James Warram, Andrzej S Krolewski, Niewczas Monika, Warram, J, Andrew Weston, Antonysunil, Adaikalakoteswari, Warram James, Krolewski Andrzej S., Niewczas, Monika, Ficociello, Linda H.   +35 more
core   +1 more source

Potensi Kedelai sebagai Nutrisiuntuk Pencegahan Nefropati Diabetes pada Penderita Diabetes Melitus

NERS Jurnal Keperawatan, 2015
Diabetes mellitus is the fourth of five causes of death in developed countries . This trend extends to developing countries and newly industrialized countries .
Putri Dafriani
doaj   +1 more source

The Heart and Diabetic Nephropathy

Methodist DeBakey Cardiovascular Journal, 2010
BACKGROUND Diabetic nephropathy represents the most common etiology for stage 5 chronic kidney disease in the United States, resulting in the need for dialysis and transplantation. It is estimated that about one-third of U.S. patients who need renal replacement therapy are diabetics.
Juan Jorge, Olivero, Peter T, Nguyen, Juan Jose, Olivero, Anna, Kagan   +3 more
openaire   +3 more sources

Multi‐Omic Profiling Reveals Immune Cell Priming Signature Linked to Lupus Prognosis

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a multiorgan disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith, Dominic Sinibaldi, Saifur Rahman, Chia‐Chien Chiang, Anna M. Hansen, Jill Henault, Carlos P. Roca, Shu Wang, Kamelia Zerrouki, Rebecca Filippi, Christopher Groves, Zerai Manna, Jun Chu, Michael Davis, Sarthak Gupta, Christopher Morehouse, Melissa de los Reyes, Rachel Ettinger, Roland Kolbeck, Mariana J. Kaplan, Miguel A. Sanjuan, Richard M. Siegel, Sarfaraz A. Hasni, Kerry A. Casey   +23 more
wiley   +1 more source

IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. IgG from patients with LN displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay, Alexia Orellana, George C. Tsokos, Rhea Bhargava   +3 more
wiley   +1 more source

Erk5 Mediates TGFβ1-induced Loss of Phenotype and Function in Human Podocytes [PDF]

, 2014
Diabetic nephropathy is one of the most common causes of renal impairment. Podocytes are specialised cells integral to normal kidney physiology, however in diabetes injury occurs leading to compromised function which is a critical factor in the ...
Irbaz I. Badshah, Irbaz Isaac Badshah, Deborah L. Baines, Dockrell, ME, Baines, DL, Mark Edward Dockrell, Mark E. Dockrell, Deborah L Baines, Badshah, II   +8 more
core   +1 more source