Results 31 to 40 of about 112,312 (307)
The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy
Journal of Diabetes Research, 2013 Diabetic nephropathy is a leading cause of end-stage renal disease worldwide. The multipronged drug approach targeting blood pressure and serum levels of glucose, insulin, and lipids fails to fully prevent the onset and progression of diabetic ...Kosuke Yamahara, Mako Yasuda, Shinji Kume, Daisuke Koya, Hiroshi Maegawa, Takashi Uzu +5 moredoaj +1 more sourceNew susceptibility Loci associated with kidney disease in type 1 diabetes [PDF]
, 2012 Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or kidney transplantation.Benjamin J. Keller (135013), Swan, E.J., Zerbini, G., Huang H., Savage, D.A., Groop L., He, Bing, Martin, Finian, Maxwell, Alexander P., Lefebvre P., Claes Ladenvall (135128), Isakova Tamara, Rosengård-Bärlund, Milla, Maestroni S., Cimponeriu Danut, Bing He, Ahola, A., Claes Ladenvall, Gill, G.V., Raija Lithovius (135051), Syreeni A., Ahola, Aila J., Aila J Ahola, Tregouet, David-Alexandre, Palmer, C., McKnight Amy Jayne, Emma Ahlqvist (135003), Kretzler M., Joel N Hirschhorn, Markku Lehto (135047), Kustaa Hietala (135040), Möllsten Anna, Anne-May Osterholm, Soro-Paavonen, A., McKnight, Amy Jayne, Robert L. Hanson (135175), Hosseini S. Mohsen, Hirschhorn, Joel, Österholm Anne-May, Tregouet David-Alexandre, Groop Leif, Groop, L., Kretzler, M., Taylor Andrew, Stavarachi Monica, Martin Finian, Eugen Mota, Böger C.A., Kustaa Hietala, Heikkilä O., Hanson, R.L., Maxwell, Alexander P; id_orcid, Tolonen Nina, Zerbini G., Bain, Stephen C., Kytö, Janne, He, Bin, Ahlqvist Emma, Hosseini, S.M., Wadén, Johan, Wadén J., Robert L Hanson, Cinzia Sarti, Groop Per-Henrik, Mollsten, Anna, Williams W.W., Cristian Serafinceanu, Andrew D Paterson, Mirel, Daniel B, Gu, Tianwei, Rigalleau V., Isakova T., Harjutsalo V., Pierre Lefebvre, Gordin D., Nina Tolonen, Syreeni, Anna, Bull S.B., Alhenc-Gelas, F., Lahermo Päivi, Boright, Andrew P, Raija Lithovius, Salem, Rany M., Keller, B., Candace Guiducci (135108), Mihai Ioana (135158), Soro-Paavonen Aino, Deshmukh H.A., Hans-Henrik Parving (135117), Sadlier, D., Österholm A.-M., Ahola Aila J., Saraheimo, Markku, Sarah Prior, Denise M Sadlier, Bing He (135034), Tregouet D.-A., Tolonen, Nina Emilia, Groop P.-H., Tikkanen, H., Palmer, Cameron, et al., Boright, A.P., Florez, Jose, Gianpaolo Zerbini, Aino Soro-Paavonen, Mota, E., Lahermo, Päivi, Hietala, Kustaa, Ladenvall, Claes, Swan E.J., Groop, Per-Henrik, Stavarachi M., Brismar, Kerstin, Williams, W., Thorn, L.M., Maria Mota (135162), Hirschhorn Joel N., Maestroni Silvia, Alhenc-Gelas, Francois, David A Savage, Harshal A. Deshmukh (135008), Söderlund Jenny, Osterholm, Anne-May, Paterson, Andrew D., Alexander P Maxwell, Waggott, D., Mäkinen, Ville-Petteri, Guiducci Candace, Salem R.M., Milla Rosengård-Bärlund (135064), McKay, Gareth J., Rosengård-Bärlund Milla, Savage D.A., Jaakko Tuomilehto, Rossing, P., Aino Soro-Paavonen (135070), Lithovius Raija, Maestroni, Silvia, David-Alexandre Tregouet (4350982), Silvia Maestroni, Rigalleau Vincent, Monica Stavarachi, DCCT/EDIC Research Group, Fagerholm E., Lehto M., Alexander P. Maxwell (135219), Rossing Peter, Prior S., Alhenc-Gelas F., McKnight, A.J., Danut Cimponeriu (135155), Henrik Falhammar, Hietala K., Fagerholm Emma, Markku Saraheimo, Deshmukh, H.A., François Alhenc-Gelas (135130), Möllsten A., Deshmukh Harshal A., Jenny Söderlund, Kytö Janne, Boright, Andrew P., Tarnow, Lise, Maestroni, S., Ahola, Aila, Tryggvason Karl, Rigalleau, Vincent, Jose C. Florez (114792), Ronan Roussel (101806), Elizabeth J. Swan (134990), Gordin Daniel, Prior Sarah, Williams, Winfred W., Salem, Rany M, Kretzler Matthias, Nelson R.G., Pitkäniemi J., Lund University., Mirel Daniel B., Söderlun, Jenny, Hans-Henrik Parving, Catherine Godson, Ronan Roussel, Ahlqvist E., Forsblom, C., David-Alexandre Tregouet, Heikkilä, Outi, Panduru Nicolae Mircea, Karl Tryggvason, Bull, S.B., Rossing, Peter, Cinzia Sarti (135068), Gill G.V., Keller, Benjamin J., McKnight, A., Brennan, E., Keller, B.J., Johan Wadén (135095), Bain Stephen C., Hadjadj S., Keller, Benjamin J, Hietala Kustaa, Lehto Markku, Matthias Kretzler (135179), McKnight, Amy Jayne; id_orcid, Gill, Geoffrey V, Tryggvason K., Gill Geoffrey V., Tamara Isakova, Lahermo P., Ahola, Aila J, Päivi Lahermo (95619), Guiducci C., Prior, S., Nicolae Mircea Panduru, Boright Andrew P., Serafinceanu Cristian, Andrew P Boright, Daniel B Mirel, Gu Tianwei, Godson, C., Maxwell A.P., Taylor, Andrew, Maxwell, A.P., Emma Fagerholm, Ville-Petteri Mäkinen, Roussel R., Harjutsalo, Valma, Heikki Tikkanen, Tryggvason, K., Mirel, Daniel B., Tolonen N., Carol Forsblom (134970), Sarti, C., Hosseini, S. Mohsen, Henrik Falhammar (135149), Huang, H., Saraheimo Markku, Parkkonen, Maija, Catherine Godson (93633), Soro-Paavonen, Aino, Tarnow, L., Mäkinen Ville-Petteri, Tikkanen Heikki, Lajer M., Amy Jayne McKnight (134964), Sadlier, Denise M., Lefebvre, P., Andrew Taylor, McKay Gareth J., Hosseini S.M., Sarti, Cinzia, Heikki Tikkanen (135079), Tuomilehto J., Bain, S.C., Martin, F., Mota, Maria, Fagerholm, Emma, Tianwei Gu (135152), Sadlier, Denise M, Per-Henrik Groop, Peter Rossing, Tarnow L., Maija Parkkonen, Sadlier Denise M., Per-Henrik Groop (135217), Milla Rosengård-Bärlund, Ville-Petteri Mäkinen (74272), Eugen Mota (135165), Florez J.C., Rany M. Salem (134961), Gareth J McKay, Daryl Waggott (135190), Parving H.-H., Joel N. Hirschhorn (131545), Leif Groop (12005), Ahlqvist, Emma, Syreeni Anna, Ahlqvist, Emma,, Gu, Harvest F., S. Mohsen Hosseini (135113), Anna Maestroni (135141), Pierre Lefebvre (135133), Serafinceanu C., Zerbini, Gianpaolo, Emma Fagerholm (135023), Winfred W. Williams (134981), Vincent Rigalleau, Peter Rossing (135121), Anna Möllsten (135153), Robert G. Nelson (135177), Niina Sandholm (134957), Ladenvall Claes, Palmer C., Fagerholm, E., Forsblom C., Guiducci, Candace, Deshmukh, H., Eoin P. Brennan (134968), Heikkila, O., Ahola A.J., He B., Rosengård-Bärlund M., Williams, Winfred, Gill, Geoffrey V., Lise Tarnow (135125), Anna Syreeni, Florez Jose C., Gianpaolo Zerbini (135187), Eoin P Brennan, Harshal A Deshmukh, Andrew D. Paterson (135194), Jaakko Tuomilehto (65635), McKay, Gareth J; id_orcid, Cimponeriu, Danut, Stavarachi, Monica, Mäkinen, V., Cameron Palmer, Kerstin Brismar (135185), Sandholm, Niina, Valma Harjutsalo (135029), Cameron Palmer (134993), Lefebvre, Pierre, Kyto, J., Thorn Lena M., Parving, Hans-Henrik, Prior, Sarah, Ladenvall C., Lena M. Thorn (135076), Deshmukh, Harshal A, Nelson, Robert G., Anna Syreeni (135072), Hadjadj Samy, Salem, R., Heikkilä Outi, Godson, Catherine, Maria Lajer (135188), Harvest F Gu, Pitkäniemi, Janne, Lithovius, Raija, Maija Parkkonen (135059), Isakova, T., Lehto, Markku, Waggott, Daryl, Bull Shelley B., Harjutsalo Valma, Lena M Thorn, Mirel, D.B., Aila J. Ahola (135020), Roussel Ronan, Mollsten, Anna,, Tolonen, Nina, Päivi Lahermo, Deshmukh, Harshal A., Ahlqvist, E., Hadjadj, S., Rigalleau, V., Outi Heikkilä, Danut Cimponeriu, Sadlier D.M., Swan, E., Gu H.F., Wadén Johan, Swan, Elizabeth J, Groop, Leif,, Panduru, Nicolae Mircea, Mäkinen, V.P., Hanson, Robert L., Paterson A.D., Daryl Waggott, Maria Mota, Daniel Gordin, Söderlund J., Bain S.C., Forsblom, Carol, Falhammar Henrik, Maxwell Alexander P., Rossing P., Helen M Colhoun, Marre Michel, Mota M., Pitkäniemi, Janne Mikael, Prior, Sarah Virginie, Janne Pitkäniemi, Carol Forsblom, Hirschhorn J.N., Gordin, D., Samy Hadjadj (91107), Gu T., Zerbini Gianpaolo, Sandholm, N., Sandholm N., Groop, P.H., McKnight A.J., Guiducci, C., Lithovius R., Swan, Elizabeth J., Saraheimo M., S Mohsen Hosseini, EDIC Research Group, DCCT/, Cristian Serafinceanu (135168), Florez, J.C., Michel Marre (91106), Savage, David A., Sarti C., Parving, H.H., Nelson Robert G., Tikkanen H., Elizabeth J Swan, Serafinceanu, C., Thorn, Lena M, Ioana M., Tarnow Lise, Mota, Eugen, Tikkanen, Heikki Olavi, Salem Rany M., Williams, Winfred W, Soderlund, J., Brismar K., Marre M., Karl Tryggvason (135087), Helen M. Colhoun (130220), François Alhenc-Gelas, Hanson R.L., Savage David A., Stephen C. Bain (135204), Candace Guiducci, Boright A.P., Andrew P. Boright (135000), Godson C., Groop, Per Henrik, Brismar, K., Niina Sandholm, Kytö J., Marre, Michel, Tregouet, D.A., Parkkonen M., Marre, M., Denise M. Sadlier (134987), Pitkäniemi Janne, Amy Jayne McKnight, Kerstin Brismar, Shelley B. Bull (135189), Falhammar, Henrik, Soro-Paavonen A., Brennan Eoin P., Waden, J., Palmer Cameron, Savage, David A, Maestroni, Anna, Janne Kytö, Maestroni, A., Geoffrey V Gill, Vincent Rigalleau (135135), Martin F., Brennan, Eoin P., Brismar Kerstin, Taylor, A., Colhoun H.M., Panduru N.M., Geoffrey V. Gill (135099), Ioana, Mihai, Mota Maria, Silvia Maestroni (135145), Williams Winfred W., Hirschhorn, J.N., Lefebvre Pierre, Michel Marre, Nelson, R.G., Palmer, Cameron Douglas, Palmer, Cameron D., Janne Pitkäniemi (28917), McKay G.J., Keller B.J., Taylor A., Ioana, M., Winfred W Williams, Falhammar H., Shelley B Bull, Outi Heikkilä (135037), Ladenvall, C., Gordin, Daniel, Mihai Ioana, Paterson Andrew D., Isakova, Tamara, Andrew Taylor (135110), Sarah Prior (135104), Bull, Shelley B., Colhoun Helen M., Monica Stavarachi (135172), Sarti Cinzia, Johan Wadén, Stephen C Bain, Mollsten, A., McKay, G., Mota Eugen, Lajer Maria, Lajer, Maria, Hanson Robert L., Thorn, Lena M., Benjamin J Keller, Anne-May Österholm (135054), Gu, T., Colhoun, Helen M., Cimponeriu D., David A. Savage (135199), Lajer, M., Falhammar, H., He Bing, Emma Ahlqvist, Lise Tarnow, Janne Kytö (135043), Dahlström, Emma Helena, Colhoun, H.M., Finian Martin (135209), Ioana Mihai, Serafinceanu, Cristian, Mirel D.B., Huateng Huang, Anna Möllsten, Swan Elizabeth J., Maestroni Anna, Syreeni, A., Huang, Huateng, Roussel, R., Hirschhorn, Joel N., Panduru, N.M., Samy Hadjadj, Mota E., Roussel, Ronan, Thorn L.M., Matthias Kretzler, Thorn, Lena, Finian Martin, Godson Catherine, Nina Tolonen (135081), Keller Benjamin J., Jenny Söderlund (135069), Nicolae Mircea Panduru (135181), Harvest F. Gu (135183), Alhenc-Gelas François, Sandholm Niina, Gu, H.F., Rany M Salem, Valma Harjutsalo, Florez, Jose C., Tikkanen, Heikki, Jose C Florez, He, B., Maria Lajer, Brennan E.P., Robert G Nelson, Stavarachi, M., Huang Huateng, Gordin, Ted Daniel, Daniel B. Mirel (110265), Gu Harvest F., Österholm, Anne May, Tryggvason, Karl, Tianwei Gu, Mota, M., Markku Lehto, Brennan, Eoin P, Söderlund, Jenny, Kretzler, Matthias, Mäkinen V.-P., Huateng Huang (135018), Parkkonen Maija, Boright, A., Tamara Isakova (134971), Waggott D., Leif Groop, Maestroni A., Forsblom Carol, Hadjadj, Samy, Groop, Leif, Paterson, A.D., Anna Maestroni, Daniel Gordin (135027), Gareth J. McKay (134975), Parving Hans-Henrik, Ladenvall, Claes,, Tuomilehto Jaakko, Cimponeriu, D., Waggott Daryl, Tuomilehto, Jaakko, Markku Saraheimo (135067) +587 morecore +1 more sourceDiabetic Nephropathy without Diabetes [PDF]
Journal of Clinical Medicine, 2015 Diabetic nephropathy without diabetes (DNND), previously known as idiopathic nodular glomerulosclerosis, is an uncommon entity and thus rarely suspected; diagnosis is histological once diabetes is discarded. In this study we describe two new cases of DNND and review the literature. We analyzed all the individualized data of previous publications except López-Revuelta, Katia, Abreu, Angel A Méndez, Gerrero-Márquez, Carmen, Stanescu, Ramona-Ionela, Marín, Maria Isabel Martínez, Fernández, Elia Pérez +5 moreopenaire +3 more sourcesBifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages
Advanced Science, EarlyView.Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun +10 morewiley +1 more sourceG6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition
Advanced Science, EarlyView.In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...Kai Liu, Boming Zhang, Ruixin Fan, Chen Duan, Yangjun Zhang, Huahui Wu, Xiangyang Yao, Xiongmin Mao, Bo Li, Youmiao Zeng, Zhenzhen Xu, Yang Wang, Mengcheng Luo, Xinyu Xu, Ninghan Feng, Heng Li, Hua Xu +16 morewiley +1 more sourceAnalysis of the Influence of Diabetic Nephropathy in Patients with Diabetic Foot Osteomyelitis [PDF]
, 2023 This study analyzed the influence of diabetic nephropathy on the healing prognosis after conservative surgery in diabetic foot osteomyelitis (DFO). A retrospective observational study was carried out between January 2021 and December 2022 and involved ...Yolanda García-Álvarez, Lopez-Moral, Mateo, Marta García-Madrid, Aroa Tardáguila-García, Álvaro Afonso, Francisco Javier, García Álvarez, Yolanda, Alvaro-Afonso, Francisco Javier, Lázaro Martínez, José Luis, López Moral, Mateo, Lazaro-Martinez, Jose Luis, Tardaguila-Garcia, Aroa, Mateo López-Moral, Tardaguila García, Aroa, Garcia-Alvarez, Yolanda, García-Madrid Martín De Almagro, Marta, José Luis Lázaro-Martínez, Francisco Javier Álvaro-Afonso, Garcia-Madrid, Marta +17 morecore +1 more source
