Results 31 to 40 of about 331,534 (287)
Cells, 2021 Diabetic kidney disease (DKD) is a frequent, potentially devastating complication of diabetes mellitus. Several factors are involved in its pathophysiology.
Claudio D. Gonzalez +4 more
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Pathomechanisms of Diabetic Kidney Disease [PDF]
Journal of Clinical Medicine, 2023 The worldwide occurrence of diabetic kidney disease (DKD) is swiftly rising, primarily attributed to the growing population of individuals affected by type 2 diabetes. This surge has been transformed into a substantial global concern, placing additional strain on healthcare systems already grappling with significant demands.
Satyesh K. Sinha, Susanne B. Nicholas
openaire +3 more sources
Advanced-Glycation End-Products Induce Podocyte Injury and Contribute to Proteinuria
Frontiers in Medicine, 2021 The prevalence of diabetes reaches epidemic proportions. Diabetes is the leading cause of end-stage kidney disease (ESKD) since 30–40% of diabetic patients develop diabetic nephropathy.
Rajkishor Nishad +6 more
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TGF-beta 1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy [PDF]
, 2010 Background/Aims: Epithelial-to-mesenchymal cell transformation (EMT) is the trans-differentiation of tubular epithelial cells into myofibroblasts, an event underlying progressive chronic kidney disease in diabetes, resulting in fibrosis.
Hills, Claire E., Squires, Paul E.
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Use of Readily Accessible Inflammatory Markers to Predict Diabetic Kidney Disease
Frontiers in Endocrinology, 2018 Diabetic kidney disease is a common complication of type 1 and type 2 diabetes and is the primary cause of end-stage renal disease in developed countries. Early detection of diabetic kidney disease will facilitate early intervention aimed at reducing the
Lauren Winter +11 more
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Aortic calcification and femoral bone density are independently associated with left ventricular mass in patients with chronic kidney disease [PDF]
, 2012 Background Vascular calcification and reduced bone density are prevalent in chronic kidney disease and linked to increased cardiovascular risk. The mechanism is unknown.
Chue, Colin D. +8 more
core +7 more sources
Dietary patterns for adults with chronic kidney disease [PDF]
, 2015 This is the protocol for a review and there is no abstract. The objectives are as follows: This review will evaluate the benefits and harms of dietary patterns among adults with CKD (any stage including people with end-stage kidney disease (ESKD) treated
Campbell, Katrina Louise +8 more
core +1 more source
Mitophagy in Diabetic Kidney Disease [PDF]
Frontiers in Cell and Developmental Biology, 2021 Diabetic kidney disease (DKD) is the most common cause of end-stage kidney disease worldwide and is the main microvascular complication of diabetes. The increasing prevalence of diabetes has increased the need for effective treatment of DKD and identification of new therapeutic targets for better clinical management.
Xiaofeng Zhang +6 more
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Baseline characteristics and enrichment results from the SONAR trial [PDF]
, 2018 Aim: The SONAR trial uses an enrichment design based on the individual response to the selective endothelin receptor antagonist atrasentan on efficacy (the degree of the individual response in the urinary albumin‐to‐creatinine ratio [UACR]) and safety/
Andress, Dennis L. +15 more
core +3 more sources
Frontiers in EndocrinologyPurposeTo evaluate the all-cause mortality rate and renal outcomes in patients with diabetes and chronic kidney disease (CKD) following hospital discharge for COVID-19.MethodsThis single-center prospective observational study included 187 discharged ...
Enrong Ran +16 more
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