Results 51 to 60 of about 5,358,430 (249)

The Pillars for Renal Disease Treatment in Patients with Type 2 Diabetes

Pharmaceutics, 2023
The diabetes epidemic and the increasing number of patients with diabetic chronic vascular complications poses a significant challenge to health care providers.
Jessica Kearney, Luigi Gnudi
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus [PDF]

, 2010
BACKGROUND: Diabetic nephropathy is a serious complication of diabetes mellitus and is associated with considerable morbidity and high mortality.
Bell Christopher G, Savage, DA, Savage, David A., Savage, D.A., Bell, CG, Beck, Stephan, Stephan Beck, Maxwell, Alexander P.; id_orcid, Maxwell, Alexander P., Maxwell, A.P., Teschendorff, AE, Beck Stephan, Rakyan, VK, Rakyan, V.K., David A Savage, Teschendorff, Andrew E., Christopher G Bell, Andrew E Teschendorff, Maxwell Alexander P, Alexander P Maxwell, Bell, Christopher G., Rakyan, Vardhman K., Savage David A, Beck, S, Rakyan Vardhman K, Bell, C.G., Beck, S., Maxwell, AP, Teschendorff, A.E., Vardhman K Rakyan, Teschendorff Andrew E   +30 more
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Matrix Metalloproteinases in Diabetic Kidney Disease [PDF]

Journal of Clinical Medicine, 2020
Around the world diabetic kidney disease (DKD) is the main cause of chronic kidney disease (CKD), which is characterized by mesangial expansion, glomerulosclerosis, tubular atrophy, and interstitial fibrosis. The hallmark of the pathogenesis of DKD is an increased extracellular matrix (ECM) accumulation causing thickening of the glomerular and tubular ...
Nuria Garcia-Fernandez, Conxita Jacobs-Cachá, José María Mora-Gutiérrez, Ander Vergara, Josune Orbe, María José Soler   +5 more
openaire   +4 more sources

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition. [PDF]

, 2021
滋賀医科大学博士（医学）pdfSGLT2 inhibitors offer strong renoprotection in subjects with diabetic kidney disease (DKD). But the mechanism for such protection is not clear.
富田, 一聖, TOMITA, Issei
core   +1 more source

Continuing medical education in renal pathology: current practices and needs among nephrologists

BMC Medical Education
Objective To investigate nephrologists’ attitudes toward renal pathology continuing medical education (CME), current problems, as well as their demands for CME Methods A self-designed questionnaire survey themed “The Value of Renal Pathology in Clinical ...
Qianqian Han, Jiamin Yuan, Lijun Zhao, Fang Liu   +3 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease [PDF]

, 2013
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Liliana Schäfer, Christian Fork (70601), Brandes, Ralf P., Brandes, Ralf, Schäfer, Liliana, Pavenstädt, Hermann, Kerstin Amann, Felix Jansen, Kerstin Sander (481042), Jung, Oliver, Ralf P Brandes, Holger Stark, Hermann Pavenstädt, Löhn, Matthias, Oliver Plettenburg (481045), Plettenburg, Oliver, Hartmut Ruetten (481044), Felix Jansen (362745), Holger Stark (4694), Christoph Daniel (282746), Liliana Schäfer (481043), Kerstin Amann (186160), Oliver Jung (362744), Ralf P. Brandes (362753), Kerstin Sander, Oliver Jung, Fork, Christian, Babelova, Andrea, Matthias Löhn, Hermann Pavenstädt (108698), Sander, Kerstin, Ruetten, Hartmut, Oliver Plettenburg, Hartmut Ruetten, Jansen, Felix, Andrea Babelova, Christian Fork, Stark, Holger, Christoph Daniel, Matthias Löhn (171195), Andrea Babelova (362749), Daniel, Christoph, Amann, Kerstin   +42 more
core   +1 more source