Results 61 to 70 of about 5,358,430 (249)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

CXCL16 and oxLDL are induced in the onset of diabetic nephropathy [PDF]

, 2009
Diabetic nephropathy (DN) is a major cause of end-stage renal failure worldwide. Oxidative stress has been reported to be a major culprit of the disease and increased oxidized low density lipoprotein (oxLDL) immune complexes were found in patients with ...
Amann, Kerstin Ute, El Sayed, El Sayed M., Doberstein, Kai, Kämpfer-Kolb, Nicole, Abdel-Aziz, Abdel-Aziz H., Schäfer, Liliana, Gutwein, Paul, Pfeilschifter, Josef, Abdel-Bakky, Mohamed Sadek, Beckmann, Janet, Doller, Anke, Schramme, Anja   +11 more
core   +1 more source

Serum C3 as an early-warning biomarker for renal pathological progression in DKD

Frontiers in Immunology
ObjectiveTo investigate the association between serum complement component 3 (C3) levels and renal pathological injury across different estimated glomerular filtration rate (eGFR) strata in patients with diabetic kidney disease (DKD) and evaluate its ...
Donghong Ma, Donghong Ma, Senle Dai, Senle Dai, Tongtong Dai, Tongtong Dai, Dandan Wang, Dandan Wang, Xue Shan, Jiao Zhang, Jiao Zhang, Jingjing Shi, Yulong Hou, Wenchao Li, Wenchao Li, Minghao Guo   +15 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Colquhounia root tablet improves diabetic kidney disease by regulating epithelial-mesenchymal transition via the PTEN/PI3K/AKT pathway

Frontiers in Pharmacology
BackgroundDiabetic kidney disease (DKD) is a severe microvascular complication of diabetes mellitus that can lead to end-stage renal disease. Colquhounia root tablet (CRT) has shown therapeutic potential in treating DKD, but its efficacy and underlying ...
Donghong Ma, Donghong Ma, Jiao Zhang, Lu Du, Jingjing Shi, Zhaoyan Liu, Zhaoyan Liu, Jilin Qin, Jilin Qin, Xiaoxiao Chen, Xiaoxiao Chen, Minghao Guo   +11 more
doaj   +1 more source

The construction of a TCM knowledge graph and application of potential knowledge discovery in diabetic kidney disease by integrating diagnosis and treatment guidelines and real-world clinical data

Frontiers in Pharmacology, 2023
Background: The complexity and rapid progression of lesions in diabetic kidney disease pose significant challenges for clinical diagnosis and treatment.
Xiaoliang Zhao, Yifei Wang, Penghui Li, Julia Xu, Yao Sun, Yao Sun, Moyan Qiu, Guoming Pang, Tiancai Wen, Tiancai Wen   +9 more
doaj   +1 more source

microRNAs in Diabetic Kidney Disease [PDF]

, 2015
Diabetes and diabetic kidney diseases have continually exerted a great burden on our society. Although the recent advances in medical research have led to a much better understanding of diabetic kidney diseases, there is still no successful strategy for effective treatments for diabetic kidney diseases.
openaire   +2 more sources

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

The eGFR-C study: accuracy of glomerular filtration rate (GFR) estimation using creatinine and cystatin C and albuminuria for monitoring disease progression in patients with stage 3 chronic kidney disease - prospective longitudinal study in a multiethnic population [PDF]

, 2014
Background: Uncertainty exists regarding the optimal method to estimate glomerular filtration rate (GFR) for disease detection and monitoring. Widely used GFR estimates have not been validated in British ethnic minority populations.
Sutton, AJ, Kevin Harris, eGFR-C study group (7648493), Khunti, Kamlesh, Brettell, Elizabeth A., Stevens, PE, Sutton, Andrew J., Claire C Sharpe, Lamb, EJ, Brettell, Elizabeth A, Cockwell, P, F. Loud (7648475), Sutton, Andrew J, P. E. Stevens (7648484), Sharpe, Claire C, Sharpe, CC, J. J. Deeks (7648466), Edmund J Lamb, Maarten W Taal, A. J. Sitch (7642292), Deeks, Jon J., R. S. Ottridge (7648478), Kamlesh Khunti, Elizabeth A Brettell, Taal, Maarten W., Khunti, K, Ottridge, Ryan, Lamb, Edmund J., Brettell, EA, Sutton, Andrew, Sharpe, Claire C., Ryan S Ottridge, Ottridge, Ryan S, ?, ?, N. Dalton (7648463), P. A. Kalra (7648472), Dalton, N, Kalra, PA, Neil Dalton, Taal, Maarten W, Taal, MW, Philip A Kalra, Sharpe, Claire C; id_orcid, Loud, F, K. Harris (75473), Tracy Higgins, Andrew J Sutton, Deeks, Jon J, Loud, Fiona, Dalton, Neil, Higgins, Tracy, Ottridge, RS, Higgins, T, Sitch, Alice J, Deeks, JJ, Sitch, AJ, M. W. Taal (7648490), T. Higgins (7648469), A. J. Sutton (7648487), Harris, Kevin, Kalra, Philip A, Paul Cockwell, Sitch, Alice J., Paul E Stevens, Ottridge, Ryan S., Harris, K, Deeks, Jonathan, Jon J Deeks, Stevens, Paul E., Sitch, Alice; id_orcid, E. J. Lamb (7648454), Kamlesh Khunti (171607), Fiona Loud, Stevens, Paul E, Kalra, Philip A., Alice J Sitch, Cockwell, Paul, P. Cockwell (7648460), Lamb, Edmund J, C. C. Sharpe (7648481), E. A. Brettell (7648457)   +80 more
core   +3 more sources

Endothelin receptor antagonists in kidney protection for diabetic kidney disease and beyond? [PDF]

, 2023
The burden of chronic kidney disease is increasing worldwide, largely due to the increasing global prevalence of diabetes mellitus and hypertension.
Hiddo J. L. Heerspink, Heerspink, Hiddo J.L., Edmund Y. M. Chung, Sunil V. Badve, Chung, Edmund Y.M., Badve, Sunil V., Wong, Muh Geot, Muh Geot Wong   +7 more
core   +2 more sources