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Microvascular Complications of Diabetes
Nursing Clinics of North America, 2006The microvascular complications of diabetes are serious, and can be life threatening. They involve injury to the blood vessels in the retina, kidney, nervous system, gingiva, and skin. Controlling the risk factors for microvascular complications involves controlling glucose level, blood pressure, and lipids, along with healthy lifestyle changes.
Marjorie Cypress, Donna Tomky
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Genetics of Diabetes and Diabetic Complications
2018Diabetes is a collection of diseases characterized by defective glucose homeostasis. Different diabetes types have different etiologies and their genetic architecture ranges from highly penetrant monogenetic diseases, such as MODY and neonatal diabetes, to polygenic diseases, such as type 1 and type 2 diabetes that are caused by numerous genetic ...
Rashmi B. Prasad+2 more
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2009
Microvascular complications are specific for diabetes and are almost certainly related to hyperglycemia (see Figure 5.1). Hyperglycemia leads to multiple biochemical changes, some of which are listed in Figure 5.2, that cause tissue damage [1, 2]. These lead to changes in various organs as summarized in Figure 5.1.
Merri Pendergrass+2 more
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Microvascular complications are specific for diabetes and are almost certainly related to hyperglycemia (see Figure 5.1). Hyperglycemia leads to multiple biochemical changes, some of which are listed in Figure 5.2, that cause tissue damage [1, 2]. These lead to changes in various organs as summarized in Figure 5.1.
Merri Pendergrass+2 more
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Microvascular complications of diabetes
Endocrinology and Metabolism Clinics of North America, 2004Several theories of the pathogenesis of microvascular complications of diabetes (diabetic retinopathy, nephropathy, and neuropathy) have been proposed: (1) generation of reactive oxygen species and oxidative stress, (2) activation of polyol pathway, (3) formation of advanced glycation end products, (4) induction of flux through the hexosamine pathway, (
George L. King, Zhiheng He
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Prevention of diabetes complications
Clinical Cornerstone, 1998Basic and clinical research findings have led to an increased understanding about diabetes and its complications. Therapeutic approaches are now based not only on predicted effects from epidemiologic, correlative, or retrospective analyses, but often on prospective intervention trials comparing a new form of therapy to the standard methods.
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The genetics of diabetic complications
Clinics in Endocrinology and Metabolism, 1986Duration of disease is the major susceptibility factor for microangiopathy. Microangiopathy does not occur without the metabolic abnormality of diabetes and there is much circumstantial evidence to implicate poor diabetic control in its pathogenesis.
A. H. Barnett, D.A. Pyke
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ACE2 and Diabetic Complications
Current Pharmaceutical Design, 2007Angiotensin converting enzyme (ACE) is a key enzyme in the renin angiotensin system (RAS) and converts angiotensin (Ang) I to the vasoconstrictor Ang II, which is thought to be responsible for most of the physiological and pathophysiological effects of the RAS.
Rachael G Dean, Louise M Burrell
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Neurologic Complications of Diabetes
Current Neurology and Neuroscience Reports, 2014Neuropathy as a complication of diabetes is common and presents in a wide variety of clinical scenarios. Often the work-up is one of exclusion tempered with monitoring the response of symptoms to treatment options. The collaboration of a neurologist is often crucial to determining the best course of action for the patient.
Nicholas V. Emanuele+2 more
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1982
Before the advent of antibiotics, the expectation of life of those who developed diabetes was considerably reduced compared with non-diabetics. Particularly when poorly controlled, diabetes reduces the resistance to infection and in the days before antibiotics were available, every illness offered a serious hazard to the diabetic.
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Before the advent of antibiotics, the expectation of life of those who developed diabetes was considerably reduced compared with non-diabetics. Particularly when poorly controlled, diabetes reduces the resistance to infection and in the days before antibiotics were available, every illness offered a serious hazard to the diabetic.
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Journal of Wound Care, 1997
A case study describing the difficulties encountered by a joint vascular and diabetic foot-care team in the management of a patient with a late ...
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A case study describing the difficulties encountered by a joint vascular and diabetic foot-care team in the management of a patient with a late ...
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