Results 241 to 250 of about 634,910 (313)
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen +10 more
wiley +1 more source
Reduced insulin use and diabetes complications upon introduction of SGLT-2 inhibitors and GLP1-receptor agonists in low- and middle-income countries: A microsimulation. [PDF]
Global Health & Population Project on Access to Care for Cardiometabolic Diseases (HPACC).
europepmc +1 more source
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He +13 more
wiley +1 more source
The Impact of Diabetes Complications on the Physical Function of Maintenance Hemodialysis Patients. [PDF]
Minata S, Kudou G, Imaoka S.
europepmc +1 more source
Nanozyme‐Integrated Hydrogel Targeting AGEs for Diabetic Osteoarthritis Therapy
A nanozyme–integrated hydrogel (PTC‐MP) exhibiting with mild photothermal effects is constructed, and a “3R” (restrain‐restore‐reinforce) strategy is proposed for diabetic osteoarthritis (DOA) treatment based on advanced glycation end products (AGEs) targeting.
Rui Chen +8 more
wiley +1 more source
Diabetes Complications among Inpatients with Childhood and Young Adult-Onset Type 1 and 2 Diabetes. [PDF]
Hawke K +7 more
europepmc +1 more source
This study presents an ultrasound‐responsive hydrogel (MCF@CA) that co‐delivers a neuropeptide (CGRP) and a ROS‐scavenging manganese porphyrin to diabetic wounds. The system restores neuro‐immune communication, reprograms macrophages toward an anti‐inflammatory phenotype, and clears excess ROS, thereby accelerating wound closure and promoting mature ...
Mofan Li +9 more
wiley +1 more source

