Results 71 to 80 of about 7,250 (205)

Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus

Nature Communications, 2017
Nrf2 regulates oxidative and electrophilic stress responses by modulating the expression of enzymes involved in detoxification pathways. Here Suzukiet al.
Takafumi Suzuki, Shiori Seki, Keiichiro Hiramoto, Eriko Naganuma, Eri H. Kobayashi, Ayaka Yamaoka, Liam Baird, Nobuyuki Takahashi, Hiroshi Sato, Masayuki Yamamoto   +9 more
doaj   +1 more source

Drug-induced metabolic acidosis [PDF]

, 2017
Summary: Drug causes of metabolic acidosis are numerous and their mechanisms are diverse. Broadly, they can cause metabolic acidosis with either a normal anion gap (e.g. drug-induced renal tubular acidosis) or an elevated anion gap (e.g.
Boton, Burdett, Burges, Dragovic, Fenves, Figge, Gerbaud, Hunter, Hussain, Kam, Karet, Knights, Kraut, Lee, Mirza, Oh, O’Connell, Peters, Porras, Reddi, Reyes, Robergs, Roscoe, Salpeter, Sawaya, Skinner, Soriano, Stewart, Tsao, Viollet, Walsh, Yombi, Yunos, Zamlauski-Tucker   +33 more
core   +1 more source

V2 vasopressin receptor mutations: future personalized therapy based on individual molecular biology

Frontiers in Endocrinology, 2023
The diluting and concentrating function of the kidney plays a crucial role in regulating the water homeostasis of the body. This function is regulated by the antidiuretic hormone, arginine vasopressin through the type 2 vasopressin receptor (V2R ...
László Sándor Erdélyi, László Hunyady, László Hunyady, András Balla, András Balla   +4 more
doaj   +1 more source

Hyperkalaemia secondary to suspected transient hyporeninaemic hypoaldosteronism in a dog (in a dog)

Veterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract A 12‐year‐7‐month‐old, female, entire beagle dog was presented to a referral hospital in England for a 10‐day history of tachypnoea and lethargy. Angiostrongylus vasorum ELISA test was positive, and the patient was started on fenbendazole. One week later, it became lethargic, anorexic, polyuric and polydipsic, and it was diagnosed with an open
Maria Jose Marin Lucas, Francesca Venier
wiley   +1 more source

Physiological basis of arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus) and AVP-resistance (AVP-R, formerly nephrogenic diabetes insipidus) [PDF]

Exploration of Medicine
This review explored the physiological mechanisms underlying arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus) and AVP resistance (AVP-R, formerly nephrogenic diabetes insipidus), with a focus on water balance regulation. Vital
Osah Martins Onwuka
doaj   +1 more source

Acquired central diabetes insipidus secondary to severe, chronic otitis media and interna in an 8‐year‐old Spanish Mastiff dog (canine)

Veterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract An 8‐year‐old spayed female Spanish Mastiff dog presented with a five‐month history of polyuria, polydipsia, persistent isosthenuria to hyposthenuria, urinary incontinence, and bilateral otitis externa, progressing to acute vestibular dysfunction.
Kevin Gooch, Kyle L. Granger Jr., Paula Yoon, Chris Olmo, Mei Lun Mui, Sarrah E. Hoppers, Kelly E. Hall   +6 more
wiley   +1 more source

Plasma Arginine Vasopressin and Serum Copeptin Concentrations at Rest and After Osmotic‐ and Non‐Osmotic‐Based Stimulation Tests in Dogs

Journal of Veterinary Internal Medicine, Volume 39, Issue 5, September/October 2025.
ABSTRACT Background Serum copeptin (sCoP) is used as a surrogate for plasma arginine vasopressin (pAVP) measurement in humans. Objective To measure pAVP and sCoP at rest and after osmotic‐ and non‐osmotic stimulation testing in dogs. Animals Eight young castrated/spayed healthy research Beagles, eight young intact dogs, and eight old neutered healthy ...
Mathieu Victor Paulin, Thomas Schermerhorn, Dorsa Mehrabanpour, Suraj Unniappan, Elisabeth Snead   +4 more
wiley   +1 more source

Nephrogenic diabetes insipidus associated with tenofovir administration: report of a paediatric case [PDF]

, 2012
Tenofovirrenal toxicity, particularly when associated with other antiretrovirals, has been reported in the adult HIV-positive population. Reports in HIVpositive children are very rare.
Costa, A., Costa, M., Faria, M., Marques, L., Mota, C., Teixeira, C.   +5 more
core  

A novel mutation affecting the arginine-137 residue of AVPR2 in dizygous twins leads to nephrogenic diabetes insipidus and attenuated urine exosome aquaporin-2 [PDF]

, 2016
Mutations in the vasopressin V2 receptor gene AVPR2 may cause X-linked nephrogenic diabetes insipidus by defective apical insertion of aquaporin-2 in the renal collecting duct principal cell.
Dieperink, Hans, Fagerberg, Christina, Hinrichs, Gitte R, Houlberg Hansen, Louise, Jensen, Boye L, Nielsen, Maria R, Rittig, Søren   +6 more
core   +1 more source

Use of copeptin in interpretation of the water deprivation test

Endocrinology, Diabetes & Metabolism, 2023
Introduction Currently, the water deprivation test remains the standard method for distinguishing primary polydipsia (PP) from cranial diabetes insipidus (cDI) and nephrogenic diabetes insipidus (nDI). There is increasing interest in a direct estimate of
Matthew Rowe, Nishchil Patel, Jinny Jeffery, Daniel Flanagan   +3 more
doaj   +1 more source