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Diabetes insipidus (DI) is a disorder characterized by a high hypotonic urinary output of more than 50ml per kg body weight per 24 hours, with associated polydipsia of more than 3 liters a day [1,2]. Central DI results from inadequate secretion and usually deficient synthesis of Arginine vasopressin (AVP) in the hypothalamus or pituitary gland. Besides
Mirjam Christ-Crain, Odile Gaisl
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Masked diabetes insipidus in pituitary metastasis from breast cancer after thalamic biopsy: a case report [PDF]
Background Symptomatic pituitary metastasis is rare; furthermore, it can result in diabetes insipidus and panhypopituitarism. Since diabetes insipidus is masked by concurrent panhypopituitarism, it can impede the diagnosis of pituitary dysfunction.
Hiroaki Hashimoto+5 more
doaj +2 more sources
Neurogenic diabetes insipidus presenting in a patient with subacute liver failure: a case report [PDF]
Introduction To the best of our knowledge, this is the first report in the literature of development of neurogenic diabetes insipidus in a patient with subacute liver failure.
O'Beirne James+5 more
doaj +5 more sources
The differential diagnosis of diabetes insipidus involves the distinction between central or nephrogenic diabetes insipidus and primary polydipsia. Differentiation is important because treatment strategies vary; the wrong treatment can be dangerous. Reliable differentiation is difficult especially in patients with primary polydipsia or partial forms of
Alyson, Weiner, Patricia, Vuguin
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Diabetes insipidus (DI) is a disorder characterized by excretion of large amounts of hypotonic urine. Central DI results from a deficiency of the hormone arginine vasopressin (AVP) in the pituitary gland or the hypothalamus, whereas nephrogenic DI results from resistance to AVP in the kidneys.
Christ-Crain, Mirjam+6 more
+8 more sources
Risk Factors and the Incidence of Diabetes Insipidus after Pituitary Surgery [PDF]
Background: To improve patient care, determining the post-surgery risk factors for diabetes insipidus are extremely significant. We demonstrated the pre-operative factors and postoperative incidence of diabetes insipidus in pituitary surgery ...
Abdul Aziz Khan+5 more
core +2 more sources
Characterization of three vasopressin receptor 2 variants: an apparent polymorphism (V266A) and two loss-of-function mutations (R181C and M311V). [PDF]
Arginine vasopressin (AVP) is released from the posterior pituitary and controls water homeostasis. AVP binding to vasopressin V2 receptors (V2Rs) located on kidney collecting duct epithelial cells triggers activation of Gs proteins, leading to increased
Armstrong, Stephen P+4 more
core +5 more sources
Ketidakseimbangan elektrolit pada pasien pasca bedah saraf sering terjadi dan berpotensi menyebabkan cedera otak sekunder yang dapat memperburuk luaran pasien, sekalipun pembedahan sukses dilaksanakan.
Dhania A Santosa+1 more
doaj +1 more source
Delay in desmopressin therapy: Disaster in waiting
There is little information on the onset of hypernatremia after withdrawal of desmopressin. We present a case of an elderly woman with central DI whose serum sodium jumped from 141 to 171 mEq/L after 48‐72 h of holding oral desmopressin. Based on this precipitous onset of DI crisis, we recommend not withholding desmopressin for more than 24 h. Abstract
Christian Kroll, Arya Zandvakili
wiley +1 more source