Results 21 to 30 of about 1,043,887 (211)
Degradation of vasopressin precursor and pathogenic mutants in diabetes insipidus [PDF]
The nonapeptide hormone, arginine vasopressin, plays a decisive role in the regulation of fluid balance by reducing free water clearance through reabsorption of water in the renal collecting ducts.
Friberg, Michael
core +1 more source
We present a rare case of transient central diabetes insipidus occurring in the setting of endoscopic sinus surgery, without evidence of structural intracranial/pituitary complications. Other etiologic factors were excluded.
Muhammad Ansar +4 more
doaj +1 more source
This paper aims to introduce a patient with Chiari type 1 malformation presented with upper extremity pain and diabetes insipidus. After laboratory examinations, we confirmed our case's central diabetes insipidus diagnosis.
Faramarz Roohollahi +3 more
doaj +1 more source
Background Symptomatic pituitary metastasis is rare; furthermore, it can result in diabetes insipidus and panhypopituitarism. Since diabetes insipidus is masked by concurrent panhypopituitarism, it can impede the diagnosis of pituitary dysfunction.
Hiroaki Hashimoto +5 more
doaj +1 more source
Fibrillar aggregations of pathogenic pro-vasopressin mutants [PDF]
Diabetes insipidus is a disregulation of water homeostasis characterized by large fluid turnover in the kidney. Water homeostasis is regulated by the hormone vasopressin by increasing reapsorption of water in the renal collecting duct. Autosomal dominant
Birk, Julia
core +1 more source
Background. Central diabetes insipidus is characterized by the inability of the kidneys to reabsorb water and concentrate urine, which is due to the defect in the synthesis or secretion of vasopressin and is manifested by severe thirst and excretion of ...
Yu.M. Urmanova, D.I. Khamraeva
doaj +1 more source
Diabetes insipidus (DI) is a disorder characterized by a high hypotonic urinary output of more than 50ml per kg body weight per 24 hours, with associated polydipsia of more than 3 liters a day [1,2]. Central DI results from inadequate secretion and usually deficient synthesis of Arginine vasopressin (AVP) in the hypothalamus or pituitary gland. Besides
Mirjam Christ-Crain, Odile Gaisl
openaire +2 more sources
Autosomal dominant familial neurohypophyseal diabetes insipidus caused by a mutation in the arginine-vasopressin II gene in four generations of a Korean family [PDF]
Autosomal dominant neurohypophyseal diabetes insipidus is a rare form of central diabetes insipidus that is caused by mutations in the vasopressin-neurophysin II (AVP-NPII) gene.
Myo-Jing Kim +3 more
doaj +1 more source
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma +5 more
wiley +2 more sources
Diabetes insipidus: Overview [PDF]
Diabetes insipidus is mainly characterized by polyuria, urinary volume over 3 L/day or 40mL/kg/day in adults, leading to subsequent polydipsia; these features are also present in most cases of diabetes mellitus.
Seema Sharma, Karam Singh
core +1 more source

