Results 51 to 60 of about 1,043,887 (211)

Diabetes insípida como forma de apresentação de leucemia mielóide aguda.

Acta Médica Portuguesa, 2004
Central diabetes insipidus, is a syndrome characterized by the excretion of abnormally elevated volumes of diluted urine, due to the diminution of reabsorption of water in the collecting ducts, induced by the diminution of production of antidiuretic ...
Susana Calretas, Sara Leitão, Emília Cortesão, Ana Isabel Espadana, Rui M Santos, Armando Porto   +5 more
doaj   +1 more source

Suprasellar Desmoplastic Infantile Ganglioglioma in a 7‐Month‐Old Infant: A Rare Diagnostic Consideration in Infant Suprasellar Masses

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Desmoplastic infantile ganglioglioma should be considered when an infant presents with a suprasellar mass, nystagmus, and developmental delay. Deep midline location limits resection, so BRAF V600E testing matters: it can open a targeted treatment option when surgery cannot control the disease.
Tawfiq Zuhair Abdullah Allaylah
wiley   +1 more source

Targeted proteomics reveal histiocytosis‐associated neurodegeneration signatures

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Neurodegeneration (ND) is a severe complication of Langerhans cell histiocytosis (LCH), yet its underlying biology and reliable biomarkers remain poorly defined. The aim of this study was to (1) gain insight into neuroimmunological mechanisms governing ND and (2) assess the clinical value of established and novel biomarkers for ND‐LCH.
Egle Kvedaraite, Magda Lourda, Johannes Bastiaan Munting, Matthias Papo, Martin Jädersten, Yoko Shioda, Kenichi Sakamoto, Daniel Martín Muñoz, Panagiotis Andriopoulos, Francesco Pegoraro, Evaldas Laurencikas, Ingrid Kühnle, Joakim Wille, Leonie Naeije, Helena Olkinuora, Indranil Sinha, Daniel W. Hagey, Selma Olsson‐Åkefeldt, Fleur Cohen‐Aubart, Gustaf Österlundh, Mattias Svensson, Ahmed Idbaih, Fredrik Piehl, Kaj Blennow, Henrik Zetterberg, Tatiana Greenwood von Bahr, Désirée Gavhed, Akira Morimoto, Julien Haroche, Jan‐Inge Henter   +29 more
wiley   +1 more source

Langerhans Cell Histiocytosis in Adults: A Canadian Multicenter Case Series

Hematological Oncology, Volume 44, Issue 5, September 2026.
ABSTRACT Langerhans cell histiocytosis (LCH) is a rare clonal myeloid neoplasm. Canadian data on clinical characteristics, molecular profile, and treatment outcomes is limited. This study aims to report the initial experience of a Canadian rare diseases program, reflecting “real‐world” diagnostic pathways, referral patterns, and treatment heterogeneity
Stephanie Quon, Yaswanta Gummadi, Ibrahim Elsharawi, Jessica Dobson, Mariam Goubran, Ryan J. Stubbins, Eli L. Diamond, Luke Y. C. Chen   +7 more
wiley   +1 more source

FGF-21 levels in polyuria-polydipsia syndrome

Endocrine Connections, 2018
The pathomechanism of primary polydipsia is poorly understood. Recent animal data reported a connection between fibroblast growth factor 21 (FGF-21) and elevated fluid intake independently of hormonal control by the hormone arginine-vasopressin (AVP) and
Julie Refardt, Clara Odilia Sailer, Bettina Winzeler, Matthias Johannes Betz, Irina Chifu, Ingeborg Schnyder, Martin Fassnacht, Wiebke Fenske, Mirjam Christ-Crain   +8 more
doaj   +1 more source

Iron Phenotypes and Reports of Menses, Pregnancies, and Live Births in Females With HFE p.C282Y Homozygosity and HFE wt/wt: A Cross‐Sectional Study

Reproductive, Female and Child Health, Volume 5, Issue 3, September 2026.
ABSTRACT Objective To compare iron phenotypes and questionnaire reports about menses, pregnancies, and live births in females with HFE p.C282Y (rs1800562) homozygosity (Y/Y) and HFE wt/wt (absence of p.C282Y and p.H63D (rs1799945) (wt/wt)). Methods We compared post‐screening iron phenotypes and questionnaire reports of self‐identified non‐Hispanic ...
James C. Barton, J. Clayborn Barton, Ronald T. Acton   +2 more
wiley   +1 more source

Thunderclap headache caused by a pituitary non-functioning tumour presenting as spontaneous pituitary apoplexy [PDF]

Romanian Journal of Neurology, 2010
Hemorrhagic or ischemic pituitary apoplexy is a rare neuro-endocrine emergency, potentially leading to coma. Neuro-ophthalmic symptoms or complications are amongst the most prevalent clinical features at onset, especially in previously asymptomatic ...
Carmen E. Georgescu, Ioana Ilie, Florina Moldovan, Horatiu Stan, Silviu Albu, Ileana Duncea   +5 more
doaj   +1 more source

Severe Hypernatraemia Secondary to Adipsia Associated With a Pituitary Macroadenoma in a Dog: A Case Report

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Severe hypernatraemia (Na+ 192 mmol/L) secondary to adipsia was successfully managed through gradual sodium correction, close monitoring and assisted water supplementation in a dog with a pituitary macroadenoma. No neurologic complications occurred during correction, and serum sodium concentrations remained stable for 9 months. This case highlights the
Gyo‐Bin Choo, Bum‐kyu Choi, Sooyoung Choi, Daji Noh, Ju‐Hyun An   +4 more
wiley   +1 more source

Diagnostic Yield and Clinical Impact of Comprehensive WES/WGS Testing Beyond Common Genetic Causes in Hereditary Optic Atrophy

Clinical Genetics, Volume 110, Issue 3, Page 336-346, September 2026.
Opticus atrophy—Genetic testing with WES/WGS in 62 patients with optic atrophy provided a genetic diagnosis in 21 patients (33.9%). 42.9% of these involved non‐OPA1 genes, including WFS1, ACO2, NR2F1, UCHL1, CACNA1F, and COQ2, where the genetic diagnosis prompted additional clinical evaluation, surveillance, or therapeutic intervention.
Katrine M. Johannesen, Karen Grønskov, Line Kessel, Sarah Linea von Holstein, Lisbeth Birk Møller, Mette Kjøbæk Gundestrup Andersen, Marianne Søndergaard Khinchi, Steffen Hamann, Marianne Wegener, Mette Bertelsen   +9 more
wiley   +1 more source

Diabetes insipidus: The other diabetes

Indian Journal of Endocrinology and Metabolism, 2016
Diabetes insipidus (DI) is a hereditary or acquired condition which disrupts normal life of persons with the condition; disruption is due to increased thirst and passing of large volumes of urine, even at night. A systematic search of literature for DI was carried out using the PubMed database for the purpose of this review.
Sanjay Kalra, Abdul Hamid Zargar, Sunil M Jain, Bipin Sethi, Subhankar Chowdhury, Awadhesh Kumar Singh, Nihal Thomas, A G Unnikrishnan, Piya Ballani Thakkar, Harshad Malve   +9 more
openaire   +3 more sources