Results 191 to 200 of about 1,509,047 (296)

Safety of teplizumab in patients with high-risk for diabetes mellitus type 1: A systematic review. [PDF]

open access: yesWorld J Diabetes
Buddhavarapu V   +5 more
europepmc   +1 more source

Clotrimazole‐loaded PLGA microparticles for local drug delivery to the vagina: Shape does matter

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Clotrimazole‐loaded PLGA microparticles for intravaginal delivery. Abstract Background Intravaginal drug administration is the most promising strategy for treating vaginal infections to protect women's health, such as vulvovaginal candidiasis (VVC). However, conventional vaginal formulations in the clinic face challenges such as drug leakage and low ...
Yanyu Li   +8 more
wiley   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Combined Superior Capsular Reconstruction and Lower Trapezius Transfer Using an Achilles Tendon Allograft Show Better Clinical Outcomes and Lower Graft Tear Rates Versus Isolated Superior Capsular Reconstruction for Chronic Posterosuperior Irreparable Massive Rotator Cuff Tears With Severe Fatty Infiltration in the Infraspinatus

open access: yesArthroscopy, EarlyView.
Purpose To compare the surgical outcomes of superior capsular reconstruction (SCR) combined with lower trapezius transfer (LTT) using an Achilles tendon allograft versus isolated SCR for the treatment of posterosuperior irreparable massive rotator cuff tears with severe infraspinatus fatty infiltration (Goutallier grades 3‐4).
Hui Ben   +3 more
wiley   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola   +14 more
wiley   +1 more source

Retinal Perfusion Analysis of Children with Diabetes Mellitus Type 1 Using Optical Coherence Tomography Angiography. [PDF]

open access: yesJ Pers Med
Vasilijevic J   +9 more
europepmc   +1 more source

Clock genes regulate Ca2+ signaling and mitochondrial bioenergetics to inhibit Sjogren's disease

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjogren's disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA seq, and mitochondrial activity were used to investigate the effects of ...
Viktor R. Drel   +12 more
wiley   +1 more source

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