Results 61 to 70 of about 111,646,599 (298)

Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population [PDF]

, 2008
Background Recent studies have implicated variants of the transcription factor 7-like 2 (TCF7L2) gene in genetic susceptibility to type 2 diabetes mellitus in several different populations. The aim of this study was to determine whether variants of this
Barnett Anthony H, Barnett, Anthony, Britten, Abigail C., Bellary, S, Barnett, Anthony H., Anthony H Barnett, Kumar Sudhesh, Britten, Abigail, Sudhesh Kumar, Rees, Simon D., Rees, Simon, Kelly, M. Ann, Kelly, Marilyn, Britten Abigail C, Kelly M Ann, Bellary, Srikanth, Rees Simon D, Srikanth Bellary, Abigail C Britten, J Paul O'Hare, Bellary Srikanth, O'Hare, JP, Kumar, Sudhesh, Simon D Rees, Barnett, A. H., O'Hare J Paul, Kumar, S, O'Hare, J. Paul, M Ann Kelly   +28 more
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Glycogenic Hepatopathy in Type 1 Diabetes Mellitus

Case Reports in Hepatology, 2015
Glycogenic hepatopathy is a rare cause of high transaminase levels in type 1 diabetes mellitus. This condition, characterized by elevated liver enzymes and hepatomegaly, is caused by irreversible and excessive accumulation of glycogen in hepatocytes ...
Murat Atmaca, Rifki Ucler, Mehmet Kartal, Ismet Seven, Murat Alay, Irfan Bayram, Sehmus Olmez   +6 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Blood glucose monitoring in children and adolescents with Type 1 Diabetes Mellitus [PDF]

, 2013
Aim: The aims of this review are to explore and quantify the importance of blood glucose monitoring on glycaemic control in children and adolescents with Type 1 Diabetes Mellitus (T1DM).
Formosa, Nancy
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Vitamin D supplementation in patients with diabetes mellitus type 2 on different therapeutic regimens : a one-year prospective study [PDF]

, 2013
Background Little or no research has determined the effect of vitamin D3 supplementation in conjunction with pharmacological and non-pharmacological approaches in the diabetes mellitus type 2 (DMT2) patients. The objective of this study was to determine
Majed S Alokail, Al-Othman, Abdulaziz, Osama Moharram, Yousef Al-Saleh, Shaun B Sabico, Chrousos, George P., Kumar, Sudhesh, Sabico, Shaun, Abdulaziz Al-Othman, Nasser M Al-Daghri, Sudhesh Kumar, George P Chrousos, Alokail, Majed S., Al-Daghri, Nasser M., Al-Saleh, Yousef, Moharram, Osama, Alkharfy, Khalid M., Khalid M Alkharfy   +17 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Molecular and Biochemical Pathways of Catalpol in Alleviating Diabetes Mellitus and Its Complications

Biomolecules, 2021
Catalpol isolated from Rehmannia glutinosa is a potent antioxidant and investigated against many disorders. This review appraises the key molecular pathways of catalpol against diabetes mellitus and its complications.
Subrat Kumar Bhattamisra, Hui Min Koh, Shin Yean Lim, Hira Choudhury, Manisha Pandey   +4 more
doaj   +1 more source

Hypoglycemia in Type 1 Diabetes Mellitus [PDF]

Endocrinology and Metabolism Clinics of North America, 2010
Iatrogenic hypoglycemia, typically the result of the interplay of therapeutic hyperinsulinemia and compromised defenses resulting in hypoglycemia-associated autonomic failure (HAAF) in diabetes, is a problem for people with type 1 diabetes mellitus (T1DM).
openaire   +2 more sources

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Skin microvascular reactivity in children and adolescents with type 1 diabetes in relation to levels of physical activity and aerobic fitness [PDF]

, 2008
No studies to date have evaluated the relationship between exercise and microvascular function in youth with type 1 diabetes mellitus (T1DM). Twenty-nine complication free children and adolescents with T1DM were assessed for skin microvascular reactivity,
Cable, Tim, Roche, Denise, Stratton, Gareth, Roche, Denise M., Edmunds, Sarah, Didi, Mo   +5 more
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