Results 111 to 120 of about 1,505,406 (304)

Early Maladjustment Schemas in Individuals with and without Type 2 Diabetes Mellitus [PDF]

, 2019
Objective. This study explored Early Maladjustment Schemas (EMSs) among individuals with and without type 2 diabetes mellitus and examined potential moderating roles for gender, level of education, and occupation. Methods.
Gholamrezaei, Simin, Khodarahimi, Siamak, Mirdrikvand, Fazlolah, Rahimian Bougar, Mojtaba, Sepahvandi, Mohamad Ali, Shafikhani, Pejman   +5 more
core   +1 more source

Mesencephalic Astrocyte‐Derived Neurotrophic Factor Binds BAX to Preserve Mitochondrial Homeostasis and Energy Metabolism for Relieving Myocardial Hypertrophy

Advanced Science, EarlyView.
MANF in cardiomyocytes interacts with BAX to impede BAX mitochondrial translocation and cytochrome c release, further stabilizing mitochondrial structure and energy supply to relieve myocardial apoptosis and hypertrophy, which indicates MANF as a novel cardioprotective factor to have a promising clinical application for myocardial hypertrophy ...
Dong Wang, Xinru Zhang, Baolong Wang, Haipeng Li, Dongshuo Xu, Yun Yang, Jialu Zhang, Wenbing Wang, Ren Zhang, Xinyu Wang, Yunfeng Cai, Shiyu Cao, Chao Hou, Changhui Wang   +13 more
wiley   +1 more source

Asprosin Aggravates Tubular Epithelial Cell Injury and Phenotypic Transformation via Mitochondrial Dynamics Disorder Mediated by Excessive Drp1 SUMOylation in Diabetic Nephropathy Mice

Advanced Science, EarlyView.
ASP aggravates TEC injury and phenotypic transformation via mitochondrial dynamics disorder mediated by excessive Drp1 SUMOylation in DKD mice. However, either ASP deficiency or AASP effectively alleviates the kidney injury and mitochondrial dynamics disorder induced by STZ/HFD, highlighting that ASP could be an early diagnostic marker and potential ...
Qianqian Huang, Xiaowei Xiong, Sheng Chen, Yuan Wang, Li Wang, Wentao Liu, Chen Liu, Guohua Zeng, Qiren Huang   +8 more
wiley   +1 more source

Khat Chewing and Type 2 Diabetes Mellitus

Diabetes, Metabolic Syndrome and Obesity, 2020
Mohammed Badedi,1 Hussain Darraj,1 Abdulrahman Hummadi,1 Abdullah Najmi,2 Yahiya Solan,1 Ibrahim Zakry,1 Abdullah Khawaji,1 Sayedah Zaylai,1 Norah Rajeh,1 Hassan Alhafaf,1 Wali Hakami,1 Awaji Bakkari,1 Maryam Kriry,1 Abdulraheem Dagreri,1 Ebrahim Haddad1
Badedi M, Darraj H, Hummadi A, Najmi A, Solan Y, Zakry I, Khawaji A, Zaylai S, Rajeh N, Alhafaf H, Hakami W, Bakkari A, Kriry M, Dagreri A, Haddad E   +14 more
doaj  

Type 2 Diabetes Mellitus and Cognitive Impairment

Acta Medica Indonesiana, 2021
Type 2 diabetes mellitus (T2DM) is strongly associated with lower performance on multiple domains of cognitive function and with structural abnormalities of the brain.
Johanda Damanik, Em Yunir
doaj  

Bright Renoprotective Properties of Metformin Beyond Blood Glucose Regulatory Effects [PDF]

, 2013
Metformin, a biguanide drug, is widely prescribed to treat high blood glucose in individuals with type 2 diabetes mellitus. Type 2 diabetes mellitus is a troubling chronic disease and diabetic nephropathy is one of the most important complications of ...
Ardalan, Mohammadreza., Baradaran, Azar., Mardani, Saeed., Momeni, Ali., Nasri, Hamid., Rafieian-Kopaei, Mahmoud.   +5 more
core  

Closed‐Loop Bioelectronic Artificial Pancreas Patch for Continuous Monitoring and Regulation of Blood Glucose in Diabetic Rats and Pigs

Advanced Science, EarlyView.
A closed‐loop bioelectronic artificial pancreas patch is presented for glucose monitoring and regulation. Utilizing transiently dissolvable microneedle arrays integrated with microtube arrays, the patch efficiently delivers insulin into interstitial fluid, eliminating the need for external long needles. In diabetic pigs, it demonstrates excellent blood
Yiqun Liu, Changxi Zhang, Lingyi Xu, Yuan Ma, Yuanyuan Ma, Ying Chen, Difei Lu, Le Ye, Li Yang, Yue Cui   +9 more
wiley   +1 more source

Type 2 Diabetes Mellitus And Vitamin C

Journal of Bahria University Medical and Dental College, 2019
Type 2 diabetes mellitus (DM) is a chronic disease which deteriorates the quality of life with time. Type 2 DM accounts for more than 90% cases of diabetes mellitus as compared to other types of this disease.
Shabzain Ishrat, Talea Hoor, Mohammed Sajid Abbas Jaffri   +2 more
doaj   +1 more source

CGRP‐Loaded ROS‐Responsive Hydrogel Restores Neuro‐Angiogenic Signaling to Promote Bone Regeneration in Diabetes‐Associated Periodontitis

Advanced Science, EarlyView.
This study shows that diabetes damages sensory nerve fibers, especially CGRP‐positive ones, in the periodontium and disrupts autophagy in trigeminal ganglion neurons, affecting bone homeostasis by inhibiting type H vessel formation. To address this, CGRP@PVA/tsPBA hydrogels are developed to release CGRP in response to ROS, which binds to endothelial ...
Chaoning Zhan, Qingyi Dai, Jianhan Ren, Lijian Jin, Weiping Wang, Zhou Ye, James Kit Hon Tsoi, Yifan Lin   +7 more
wiley   +1 more source

HUBUNGAN LAMA MENDERITA DIABETES MELLITUS TIPE 2 TERHADAP PENURUNAN FUNGSI KOGNITIF PADA PASIEN LANJUT USIA [PDF]

, 2016
ABSTRAKGangguan kognitif sering dijumpai pada penderita Diabetes Mellitus (DM) sebagai akibat dari komplikasi mikrovaskular maupun makrovaskuler. Sampai saat ini studi yang meneliti hubungan lama menderita DM dengan gangguan fungsi kognitif masih ...
Syarifah Sulfira Mulia
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