Results 231 to 240 of about 1,541,306 (306)

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation using antiarrhythmic drugs: An international cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Our international cohort study assessed the comparative effectiveness and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) among patients with non‐valvular atrial fibrillation (NVAF) using antiarrhythmic drugs. Methods Using the United Kingdom's (UK's) Clinical Practice Research Datalink Aurum and Québec claims data, we
Fabian Maximilian Meinert   +5 more
wiley   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

open access: yesBMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang   +12 more
wiley   +1 more source

Advances in Pharmacological Insights of Borago officinalis: A Comprehensive Review

open access: yesBiological Diversity, EarlyView.
ABSTRACT Recent growth in phytotherapy and product‐based drug development has increased interest in this plant because of its broad pharmacological activity. This review aims to examine the pharmacological activities, mechanisms, and potential applications of Borago officinalis, focusing on its primary bioactive constituents and therapeutic ...
Zahra Sufwan   +2 more
wiley   +1 more source

Biologically‐oriented alveolar ridge preservation to correct bone dehiscence at immediate implant placement

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background The purpose of the present case study is to describe the application of a modification of the Biologically‐oriented Alveolar Ridge Preservation (BARP) principles in cases of peri‐implant bone dehiscence (PIBD) due to a compromised alveolus at immediate implant placement (IIP).
Leonardo Trombelli, Tommaso Grenzi
wiley   +1 more source

Multifaceted Study of Medicago marina Essential Oil: Chemical Composition, Antidiabetic, and Phytotoxic Insights via In Vitro and In Silico Approaches

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The essential oil of Medicago marina was subjected to analysis at vegetative and reproductive stages of development, with a particular emphasis on its chemical composition, α‐amylase inhibition, and allelopathic activities. The results of the gas chromatography and molecular docking studies demonstrated alterations in oil yield and composition
Marwa Melliti   +9 more
wiley   +1 more source

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