Results 71 to 80 of about 432,092 (116)
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Intestinal hyperemia in experimental diabetes mellitus
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1987Intestinal blood flows were measured using the radioactive microsphere technique in anesthetized, fasted (18–24 h) rats 4 wk after administration of streptozotocin (65 mg/kg body wt) or its vehicle. Blood flow was increased along the length of the small bowel in diabetic rats relative to normal animals.
R J, Korthuis +5 more
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Fatty Acid Desaturation in Experimental Diabetes Mellitus
Diabetes, 1979Microsomal fatty acid desaturation is defective in streptozotocin-induced experimental diabetes. This defect is correctable by insulin treatment. The electron transport chain needed for microsomal fatty acid desaturation was studied in liver microsomes of streptozotocin diabetic rats, and the defect was localized to the terminal desaturase enzyme ...
M G, Eck +3 more
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Insulin Resistance in Experimental Type 1 Diabetes Mellitus
Bulletin of Experimental Biology and Medicine, 2021Experimental type 1 diabetes mellitus (T1DM) was induced in rats by daily intraperitoneal injections of alloxan in a dose of 90 mg/kg for 4 days. For verification of insulin resistance, insulin tolerance test was performed in 2 weeks and the glucose utilization rate constant (KITT) was calculated.
V V, Ivanov +7 more
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Experimental diabetes and its relation to diabetes mellitus
The American Journal of Medicine, 1955Summary A few selected possibilities about the nature, causation and measurement of experimental diabetes have been outlined. A modest comprehension of these experimental experiences should be of some help in the management and study of the disease in man.
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Experimental study of corneal innervation in diabetic mellitus
Journal of Tongji Medical University, 1995The morphology of corneal innervation was studied in rabbits with alloxan-induced diabetes. The experimental rabbits were killed after 6, 8, 10, 12 weeks. Corneal innervation was studied by histochemical techniques and transmission electron microscopy.
J Y, Li, C K, Mai, Y H, Hu, Y L, He
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Diabetes Mellitus in Man and Experimental Animals
Annals of Internal Medicine, 1967Excerpt In a recent communication, scientists at the Jackson Laboratory in Bar Harbor, Me., reported a mutation (db) in an inbred strain of mice which is inherited as an autosomal-recessive trait a...
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Experimental production of diabetes mellitus by a nonendocrinal approach
Nature, 1974THE immunofluorescent demonstration of large deposits of fibrin in the microvascular lesions1,2, and evidence of a slow consumptive fibrinocoagulopathy in maturity onset diabetes mellitus3,4, suggested the possibility of a primary fibrinocoagulopathic vascular aetiopathogenesis of the disorder.
R N, Banerjee, S, Rao, J, Bardhan
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Impaired Arteriolar Mechanotransduction in Experimental Diabetes Mellitus
Journal of Diabetes and its Complications, 1999Decreased arteriolar distensibility in diabetes may impair signal transduction mechanisms that are required for converting a pressure stimulus into smooth muscle contraction. These studies aimed to determine if pressure-induced increases in arteriolar intracellular Ca(2+) are altered in diabetes and whether diabetes is associated with alterations in ...
G, Yu, H, Zou, R L, Prewitt, M A, Hill
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Microvascular Anastomotic Thrombosis in Experimental Diabetes Mellitus
Plastic and Reconstructive Surgery, 1997An experimental model was developed to investigate the effects of glycemic control and pentoxifylline administration on microvascular anastomotic patency rates in streptozotocin-induced diabetic rats. Diabetes was confirmed by blood glucose levels of more than 300 mg/dl prior to administering insulin and/or pentoxifylline.
L B, Colen +7 more
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Intestinal capillary filtration in experimental diabetes mellitus
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1987There is indirect evidence that indicates that intestinal transcapillary fluid and solute exchange is significantly altered in diabetes mellitus. To directly assess the dynamics of microvascular fluid and solute exchange in the small intestine (jejunum-ileum), we measured lymph flow, capillary pressure, capillary filtration coefficient, plasma and ...
R J, Korthuis, V H, Pitts, D N, Granger
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