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Experimental Diabetes Mellitus in Different Animal Models [PDF]
Journal of Diabetes Research, 2016 Animal models have historically played a critical role in the exploration and characterization of disease pathophysiology and target identification and in the evaluation of novel therapeutic agents and treatments in vivo.
Amin Al-awar +8 more
doaj +6 more sources
Antioxidants, 2019 Diabetes mellitus has become a serious and growing public health concern. It has high morbidity and mortality because of its complications, such as diabetic nephropathy, diabetic cardiovascular complication, diabetic neuropathy, diabetic retinopathy, and
Jin-Ming Meng +8 more
doaj +2 more sources
International Journal of Molecular Sciences, 2022 The present study aims to compare the oxidative stress biomarkers, pro-inflammatory cytokines, and histological changes induced by three cardiovascular risk factors, namely, hypertension, dyslipidemia, and type 1 diabetes mellitus.
Paul-Mihai Boarescu +11 more
semanticscholar +1 more source
Bulletin of experimental biology and medicine, 2021 The review presents modern views about the role of oxidative stress reactions in the pathogenesis of types 1 and 2 diabetes mellitus and their complications based on the analysis of experimental and clinical studies.
M. Darenskaya +2 more
semanticscholar +1 more source
The role of selenium in type-2 diabetes mellitus and its metabolic comorbidities
Redox Biology, 2022 This review addresses the role of the essential trace element, selenium, in type-2 diabetes mellitus (T2DM) and its metabolic co-morbidities, i.e., metabolic syndrome, obesity and non-alcoholic fatty liver disease. We refer to the dietary requirements of
H. Steinbrenner, L. Duntas, M. Rayman
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2020 Liraglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), has been demonstrated to alleviate non-alcoholic fatty liver disease (NAFLD). However, the underlying mechanism has not been fully elucidated.
Yunyun Fang +8 more
doaj +1 more source
Cardiovascular Diabetology, 2022 Chemokines are key components in the pathology of chronic diseases. Chemokine CC motif ligand 7 (CCL7) is believed to be associated with cardiovascular disease, diabetes mellitus, and kidney disease.
Ting-Ting Chang +2 more
semanticscholar +1 more source
Бюллетень сибирской медицины, 2022 Persistent hyperglycemia resulting from diabetes mellitus causes microvascular lesions and long-term diabetic complications, such as nephropathy.The aim of the study was to analyze the levels of insulin-like growth factors (IGFs), their carrier proteins (
E. M. Frantsiyants +9 more
doaj +1 more source
The links between sleep duration, obesity and type 2 diabetes mellitus
Journal of Endocrinology, 2021 Global rates of obesity and type 2 diabetes mellitus (T2DM) are increasing globally concomitant with a rising prevalence of sleep deprivation and sleep disorders.
C. Antza +4 more
semanticscholar +1 more source
Diagnosis of Diabetes Mellitus Using Gradient Boosting Machine (LightGBM)
Diagnostics, 2021 Diabetes mellitus (DM) is a severe chronic disease that affects human health and has a high prevalence worldwide. Research has shown that half of the diabetic people throughout the world are unaware that they have DM and its complications are increasing,
Derara Duba Rufo +3 more
semanticscholar +1 more source