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Experimental Approaches to Diabetes Mellitus

open access: yesEurasian Journal of Medicine, 2022
One of the most common health problems today, diabetes is a serious, chronic, and complex disease characterized by high blood glucose levels. Nowadays, experimental diabetes models are being developed to study existing diabetes in depth, to improve diabetes medications, or to develop new medications.
Muhammed Yayla, Damla Binnetoğlu
doaj   +3 more sources

Experimental Diabetes Mellitus in Different Animal Models [PDF]

open access: yesJournal of Diabetes Research, 2016
Animal models have historically played a critical role in the exploration and characterization of disease pathophysiology and target identification and in the evaluation of novel therapeutic agents and treatments in vivo.
Amin Al-awar   +8 more
doaj   +6 more sources

How to create an experimental diabetes mellitus model? [PDF]

open access: yesPharmacia, 2023
Diabetes is a metabolic disorder characterized by chronic hyperglycemia. Early treatment is very important in terms of preventing diabetes-related late complications with high treatment costs and increasing the patient’s quality of life.
Rabia Edibe Parlar Köprülü
doaj   +6 more sources

Experimental Gestational Diabetes Mellitus Prolongs Post-Incisional Mechanical Hypersensitivity and Increases Cutaneous Neuro-Immune Markers in Adult Female Offspring [PDF]

open access: yesJournal of Pain Research
Carlos A Cantú-Cepeda, Jaira Villarreal-Salcido, Cecilia Esther Elizondo-Martinez, Juan Antonio Vazquez-Mora, Arisai Martínez-Martínez, Rosa Issel Acosta-González, Juan Miguel Jiménez-Andrade, Enriqueta Muñoz-Islas Laboratory of Pharmacology ...
Cantú-Cepeda CA   +7 more
doaj   +2 more sources

Liraglutide Alleviates Hepatic Steatosis by Activating the TFEB-Regulated Autophagy-Lysosomal Pathway

open access: yesFrontiers in Cell and Developmental Biology, 2020
Liraglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA), has been demonstrated to alleviate non-alcoholic fatty liver disease (NAFLD). However, the underlying mechanism has not been fully elucidated.
Yunyun Fang   +8 more
doaj   +1 more source

Insulin-like growth factors and their carrier proteins in kidneys of rats with experimental diabetes, malignant tumor, and their combination

open access: yesБюллетень сибирской медицины, 2022
Persistent hyperglycemia resulting from diabetes mellitus causes microvascular lesions and long-term diabetic complications, such as nephropathy.The aim of the study was to analyze the levels of insulin-like growth factors (IGFs), their carrier proteins (
E. M. Frantsiyants   +9 more
doaj   +1 more source

DOSE DEPENDENT EFFECT OF GLYCYRRHIZIN ON GLYCAEMIC CONTROL OF TYPE 2 DIABETIC RATS

open access: yesKhyber Medical University Journal, 2020
OBJECTIVE: To assess the effect of low and high dose of glycyrrhizin on body weight, fasting blood sugar level (FBSL), serum insulin and glycemic indices in high fat diet induced type 2 diabetic rats.
Mufakhara Fatimah   +5 more
doaj   +1 more source

Avaliação de parâmetros de cicatrização no cólon de ratos diabéticos sem agressão cirúrgica [PDF]

open access: yesActa Cirúrgica Brasileira, 2004
OBJETIVO: Existem poucos estudos na literatura utilizando parâmetros de cicatrização em animais diabéticos antes da agressão cirúrgica e nenhum estudo no colon.
Erika Veruska Paiva Ortolan   +3 more
doaj   +1 more source

The Effect of Health Education on Knowledge of The Prevention of Diabetes Mellitus

open access: yesBabali Nursing Research, 2022
Introduction: Diabetes mellitus (DM) is a lifelong disease that cannot be cured permanently, which according to WHO estimates the number of people with diabetes will be the main cause of 7 deaths in 2030.
Dewi Wijayanti
doaj   +1 more source

Pancreatic islet isolation by mechanical-enzymatic separation, stationary collagenase digestion and dextran discontinuous density gradient purification: experimental study in dogs Isolamento das ilhotas pancreáticas pela separação mecânica-enzimática digestão estacionária com colagenase e purificação com gradiente de densidade descontínua de dextran: estudo experimental em cães

open access: yesActa Cirúrgica Brasileira, 2002
The prospects for allotransplantation of pancreatic islets in man depend on the development of methods that provide sufficient quantities of pancreatic islets from a single donor, which are capable, when transplanted, of achieve the normalization of ...
Jaques Waisberg   +4 more
doaj   +1 more source

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