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Experimental Approaches to Diabetes Mellitus

open access: yesEurasian Journal of Medicine, 2022
One of the most common health problems today, diabetes is a serious, chronic, and complex disease characterized by high blood glucose levels. Nowadays, experimental diabetes models are being developed to study existing diabetes in depth, to improve diabetes medications, or to develop new medications.
Muhammed Yayla, Damla Binnetoğlu
doaj   +3 more sources

Speckle-tracking echocardiography combined with imaging mass spectrometry assesses region-dependent alterations [PDF]

open access: yes, 2020
Left ventricular (LV) contraction is characterized by shortening and thickening of longitudinal and circumferential fibres. To date, it is poorly understood how LV deformation is altered in the pathogenesis of streptozotocin (STZ)-induced type 1 diabetes
Dong, Fengquan   +10 more
core   +1 more source

Adiponectin gene polymorphisms associated with diabetes mellitus: A descriptive review

open access: yesHeliyon, 2021
Diabetes is currently a growing concern of the age. Prevention and treatment of diabetes is a global health priority. Adiponectin is an adipocyte derived protein hormone that enhances insulin sensitivity and ameliorates diabetes by enhancing fatty acid ...
Mithu Howlader   +3 more
semanticscholar   +1 more source

Vascular Reactivity in Experimental Diabetes Mellitus [PDF]

open access: yesCirculation Research, 1964
Vascular reactivity was examined in vessels of the perfused hindquarters of alloxan diabetic and control rats. A significant increase was noted in responsiveness of the diabetic animals to intra-arterial injection of epinephrine, norepinephrine, and synthetic angiotensin.
MICHAEL J. BRODY   +2 more
openaire   +2 more sources

Activation of Glucagon‐Like Peptide‐1 Receptor Ameliorates Cognitive Decline in Type 2 Diabetes Mellitus Through a Metabolism‐Independent Pathway

open access: yesJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2021
Background Patients with hypertension and diabetes mellitus are susceptible to dementia, but regular therapy fails to reduce the risk of dementia. Glucagon‐like peptide‐1 receptor agonists have neuroprotective effects in experimental studies. We aimed to
Qiang Li   +13 more
semanticscholar   +1 more source

DOSE DEPENDENT EFFECT OF GLYCYRRHIZIN ON GLYCAEMIC CONTROL OF TYPE 2 DIABETIC RATS

open access: yesKhyber Medical University Journal, 2020
OBJECTIVE: To assess the effect of low and high dose of glycyrrhizin on body weight, fasting blood sugar level (FBSL), serum insulin and glycemic indices in high fat diet induced type 2 diabetic rats.
Mufakhara Fatimah   +5 more
doaj   +1 more source

Avaliação de parâmetros de cicatrização no cólon de ratos diabéticos sem agressão cirúrgica [PDF]

open access: yesActa Cirúrgica Brasileira, 2004
OBJETIVO: Existem poucos estudos na literatura utilizando parâmetros de cicatrização em animais diabéticos antes da agressão cirúrgica e nenhum estudo no colon.
Erika Veruska Paiva Ortolan   +3 more
doaj   +1 more source

How to create an experimental diabetes mellitus model? [PDF]

open access: yesPharmacia, 2023
Diabetes is a metabolic disorder characterized by chronic hyperglycemia. Early treatment is very important in terms of preventing diabetes-related late complications with high treatment costs and increasing the patient’s quality of life.
Rabia Edibe Parlar Köprülü
doaj   +3 more sources

Heart failure is common in diabetic cats : findings from a retrospective case-controlled study in first-opinionpractice [PDF]

open access: yes, 2007
Diabetes mellitus is common in the cat and the prevalence of this condition appears to be increasing (Peterson 1998,Rand and Marshall 2004, Rand and others 2004). The prognosis for cats with diabetes mellitus in first opinion practice has received little
Blue Skies Research Grant - RCVS Trust (Funder)   +2 more
core   +1 more source

Sleep, circadian rhythms, and type 2 diabetes mellitus

open access: yesClinical Endocrinology, 2021
Over the last 60 years we have seen a significant rise in metabolic disease, especially type 2 diabetes. In the same period, the emergence of electricity and artificial lighting has allowed our behavioural cycles to be independent of external patterns of
Gokul Parameswaran, D. Ray
semanticscholar   +1 more source

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