Advanced Science, EarlyView.VCIPIP1 emerges as a molecular link between protein stability and prostate cancer progression. By deubiquitinating and stabilizing UBE3A, VCIPIP1 promotes p53 degradation and progression to castration‐resistant prostate cancer. Elevated VCIPIP1 expression is associated with shorter castration‐resistant prostate cancer–free survival, highlighting the ...
Fei Lin +9 more
wiley +1 more source
Potential Influence of Age and Diabetes Mellitus Type 1 on MSH2 (MutS homolog 2) Expression in a Rat Kidney Tissue. [PDF]
Genes (Basel), 2022 Babić P +5 more
europepmc +1 more source
Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities
AGING MEDICINE, EarlyView.Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley +1 more source
Gene expression pattern in severely progressing covid-19 patients is related to diabetes mellitus type 1: A functional annotation analysis. [PDF]
Hum Gene (Amst), 2022 Alipour M, Javeshghani D, Roustazadeh A.
europepmc +1 more source
AGING MEDICINE, EarlyView.The prevalence of sarcopenia and sarcopenic obesity is large among community‐dwelling postmenopausal women, and lower body mass index is a significant predictor of both. The finding that low body mass index predicts both sarcopenia and sarcopenic obesity, highlights the limitation of body mass index as a measure of adiposity in the assessment of ...
Remya Rajan +7 more
wiley +1 more source
COMPARISON OF URINARY ALBUMIN EXCRETION RATE IN TYPE 1 AND TYPE 2 DIABETICS OF DISTRICT LAHORE
Gomal Journal of Medical Sciences, 2014 Background: The main cause of end-stage renal disease is diabetic nephropathy throughout the world. Renal disease in diabetics is characterized by increasing rates of urinary albumin excretion, starting from normoalbuminuria, which progresses to ...
Amir Rehman +3 more
doaj
Effects of a Diabetes Sports Summer Camp on the Levels of Physical Activity and Dimensions of Health-Related Quality of Life in Young Patients with Diabetes Mellitus Type 1: A Randomized Controlled Trial. [PDF]
Children (Basel), 2023 Skoufa L +5 more
europepmc +1 more source
AGING MEDICINE, EarlyView.Among 132 older adults, 13 had peripheral artery disease (PAD), identified using the ankle–brachial index. Over approximately 13 months, PAD was associated with increasing middle cerebral artery mean flow velocity, with a significant difference in left‐sided velocity change between groups.
SangMi Noh, Hae‐Eun Shin, YongSoo Shim
wiley +1 more source
Bone Density, Geometry, and Mass by Peripheral Quantitative Computed Tomography and Bone Turnover Markers in Children with Diabetes Mellitus Type 1. [PDF]
J Diabetes Res, 2022 Jaworski M +5 more
europepmc +1 more source
Annals of Gastroenterological Surgery, EarlyView.In this multicenter prospective study of 158 working‐age patients undergoing curative‐intent surgery for gastric or esophageal cancer, 78.5% were working at 18 months. Postoperative appetite loss, financial difficulties, and ≥ 10% weight loss at 6 months were associated with non‐working status.
Kentaro Goto +18 more
wiley +1 more source