Results 41 to 50 of about 34,952,591 (247)

Dehydroepiandrosterone in the type 1 diabetes mellitus

Endocrine Regulations, 2012
Dehydroepiandrosterone (DHEA) is believed to exert, besides others, positive effects on the insulin resistance or its secretion and glucose metabolism. There are several reports dealing with the DHEA levels and its effects in the type 2 diabetes mellitus, but less information is available on the type 1 diabetic subjects. Recently, a report dealing with
M, Duskova, H, Hruskovicova, M, Hill, L, Starka   +3 more
openaire   +2 more sources

Cognitive Dysfunction in Type 1 Diabetes Mellitus [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2019
We have summarized key studies assessing the epidemiology, mechanisms, and consequences of cognitive dysfunction (CD) in type 1 diabetes.In a number of studies, the severity of CD in type 1 diabetes was affected by the age of onset and duration, and the presence of proliferative retinopathy and autonomic neuropathy.
Anna Shalimova, Beata Graff, Dariusz Gąsecki, Jacek Wolf, Agnieszka Sabisz, Edyta Szurowska, Krzysztof Jodzio, Krzysztof Narkiewicz   +7 more
openaire   +2 more sources

Skin microvascular vasodilatory capacity in offspring of two parents with Type 2 diabetes [PDF]

, 2001
Aims<br/> Microvascular dysfunction occurs in Type 2 diabetes and in subjects with fasting hyperglycaemia. It is unclear whether this dysfunction relates to dysglycaemia.
Shore, A.C., Lowe, G.D., Lee, B.C., B. C. Lee, Clark, P.M., A. Rumley, J. E. Tooke, A. T. Hattersley, Rumley, A., Tooke, J.E., G. D. Lowe, A. C. Shore, J. M. Humphreys, Humphreys, J.M., P. M. Clark, Hattersley, A.T.   +15 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Association of time in range with hemoglobin A1c, glycated albumin and 1,5‐anhydro‐d‐glucitol

Journal of Diabetes Investigation, 2021
Aims/Introduction Hemoglobin A1c (HbA1c), glycated albumin (GA) and 1,5‐anhydro‐d‐glucitol (1,5‐AG) are used as indicators of glycemic control, whereas continuous glucose monitoring (CGM) is used to assess daily glucose profiles.
Mana Ohigashi, Keiko Osugi, Yoshiki Kusunoki, Kahori Washio, Satoshi Matsutani, Taku Tsunoda, Toshihiro Matsuo, Kosuke Konishi, Tomoyuki Katsuno, Mitsuyoshi Namba, Hidenori Koyama   +10 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Glycogenic Hepatopathy in Type 1 Diabetes Mellitus

Case Reports in Hepatology, 2015
Glycogenic hepatopathy is a rare cause of high transaminase levels in type 1 diabetes mellitus. This condition, characterized by elevated liver enzymes and hepatomegaly, is caused by irreversible and excessive accumulation of glycogen in hepatocytes ...
Murat Atmaca, Rifki Ucler, Mehmet Kartal, Ismet Seven, Murat Alay, Irfan Bayram, Sehmus Olmez   +6 more
doaj   +1 more source

Uterine Arteries Resistance in Pregnant Women with Gestational Diabetes Mellitus, Diabetes Mellitus Type 1, Diabetes Mellitus Type 2, and Uncomplicated Pregnancies

Biomedicines, 2023
Background: The examination of the uterine arteries using Doppler in the first trimester of pregnancy serves as a valuable tool for evaluating the uteroplacental circulation.
Christos Chatzakis, Makarios Eleftheriades, Eleftheria Demertzidou, Anna Eleftheriades, Nikolaos Koletsos, Lazaros Lavasidis, Athanasios Zikopoulos, Konstantinos Dinas, Alexandros Sotiriadis   +8 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A gyermekkori 1-es típusú diabétesz genetikai és humorális immunológiai hátterének vizsgálata = Genetic and humoral immunologic determinants of childhood-onset type 1 diabetes [PDF]

, 2007
Az OTKA pályázat munkatervében kitűzött célok megvalósultak. A program az elmúlt három év alatt országos diabetes genetikai projektté nőtte ki magát (HUN-T1D-GENES program; www.diabet.hu/ diabetesgenetics).
Hermann, Róbert, Soltész, Gyula
core   +1 more source