Results 121 to 130 of about 1,598,216 (309)

Association of high-sensitive C-reactive protein with advanced stage beta-cell dysfunction and insulin resistance in patients with type 2 diabetes mellitus [PDF]

, 2006
Background: Type 2 diabetes mellitus is associated with increased cardiovascular risk. One laboratory marker for cardiovascular risk assessment is high-sensitivity C-reactive protein (hsCRP).
Balkau, Forst, Haffner, Haffner, Hedblad, Howard, Huupponen, Langenfeld, Maseri, Matthews, Morrow, Nissen, Paice, Pfützner, Pfützner, Pfützner, Pfützner, Pfützner, Pfützner, Pfützner, Ridker, Ridker, Ridker, Ridker, Ridker, Ridker, Riveline, Ross, Saito, Sellmayer, Serrano Rios, Simpson, Willerson, Yudkin   +33 more
core   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Bright Renoprotective Properties of Metformin Beyond Blood Glucose Regulatory Effects [PDF]

, 2013
Metformin, a biguanide drug, is widely prescribed to treat high blood glucose in individuals with type 2 diabetes mellitus. Type 2 diabetes mellitus is a troubling chronic disease and diabetic nephropathy is one of the most important complications of ...
Ardalan, Mohammadreza., Baradaran, Azar., Mardani, Saeed., Momeni, Ali., Nasri, Hamid., Rafieian-Kopaei, Mahmoud.   +5 more
core  

Impact of Prophylactic Cefepime on Surgical Site Infection and Severe Morbidity in Patients Who Underwent Pancreaticoduodenectomy With Preoperative Biliary Drainage

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Although prophylactic broad‐spectrum antibiotics can reduce postoperative complications after pancreaticoduodenectomy (PD), the optimal regimen remains uncertain. This study evaluated the impact of prophylactic cefepime (CFPM) on surgical site infection (SSI) and severe morbidity after PD with preoperative biliary drainage.
Genki Watanabe, Akihiro Murata, Yu Kasamatsu, Atsushi Ishihara, Daisuke Nagashima, Tetsuzo Tashima, Shintaro Kodai, Akishige Kanazawa, Sadatoshi Shimizu   +8 more
wiley   +1 more source

Microparticles in type 2 diabetes mellitus [PDF]

Journal of Thrombosis and Haemostasis, 2005
DAVI', Giovanni, FERRONI P.
openaire   +3 more sources

Risk Factors for Small‐for‐Size Syndrome Grade B/C After Simultaneous Splenectomy in Adult Living‐Donor Liver Transplantation

Annals of Gastroenterological Surgery, EarlyView.
In a single‐center cohort of 577 adult LDLT recipients who underwent simultaneous splenectomy, clinically significant SFSS grade B/C (ILTS‐iLDLT‐LTSI 2023) occurred in 18.2% and was associated with inferior graft survival. Multivariate analysis identified MELD ≥ 30, NLR ≥ 4.5, and donor age ≥ 50 years as independent risk factors, which risk rising ...
Kyohei Yugawa, Takeo Toshima, Shinji Itoh, Takashi Motomura, Shohei Yoshiya, Norifumi Iseda, Tomoharu Yoshizumi   +6 more
wiley   +1 more source

Hubungan Antara Lama Menderita Diabetes Melitus Tipe 2 Dengan Terjadinya Neuropati Sensorik Diabetik Di RSUD Salatiga [PDF]

, 2015
Background: Type 2 Diabetes Mellitus occurs as a result of the body's resistance to the effects of insulin produced by the pancreatic cells. Type 2 Diabetes Mellitus is the largest case in Indonesia.
, dr. Erika Diana Risanti, , dr. Nur Hidayat, Sp. PD, Lestari, Dwi   +2 more
core  

Comparison of Minimally Invasive Colectomy Between Intra‐ Versus Extra‐Corporeal Anastomosis Technique (COMMIT Study): Mid‐Term Analysis

Annals of Gastroenterological Surgery, EarlyView.
This multicenter retrospective cohort study compared mid‐term oncological outcomes between intracorporeal anastomosis (IA) and extracorporeal anastomosis (EA) in minimally invasive colectomy for colon cancer using propensity score–matched data from 2018 to 2022.
Takuya Takami, Takehito Yamamoto, Yoshiro Itatani, Ryosuke Mizuno, Shinya Hamasu, Keita Hanada, Kenji Kawada, Teppei Murakami, Satoshi Nagayama, Kazutaka Obama   +9 more
wiley   +1 more source

Perbedaan Kadar Trigliserida Pada Penderita Diabetes Melitus Tipe 2 Dengan Hipertensi Dan Tanpa Hipertensi Di RSUD Moewardi [PDF]

, 2015
Background: Hypertension is common in patients with diabetes mellitus. Hypertension also increases the risk of cardiovascular disease in diabetes mellitus. High triglyserides level was a sign of dislipidemia. Diabetes mellitus and hypertension accompined
, dr. Listiana Masyita Dewi, M.Sc, , dr. Sumardjo, Sp.PD, Siringoring, Yohana Pandora Ristua   +2 more
core