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Nature Reviews Disease Primers, 2015
Type 2 diabetes mellitus (T2DM) is an expanding global health problem, closely linked to the epidemic of obesity. Individuals with T2DM are at high risk for both microvascular complications (including retinopathy, nephropathy and neuropathy) and macrovascular complications (such as cardiovascular comorbidities), owing to hyperglycaemia and individual ...
DeFronzo, Ralph A +12 more
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Type 2 diabetes mellitus (T2DM) is an expanding global health problem, closely linked to the epidemic of obesity. Individuals with T2DM are at high risk for both microvascular complications (including retinopathy, nephropathy and neuropathy) and macrovascular complications (such as cardiovascular comorbidities), owing to hyperglycaemia and individual ...
DeFronzo, Ralph A +12 more
openaire +5 more sources
Aldosterone and type 2 diabetes mellitus
Hormone Molecular Biology and Clinical Investigation, 2016Abstract Primary hyperaldosteronism (PA) has recently been demonstrated to be strictly associated to metabolic syndrome as compared with essential hypertension (EH). Besides, the characteristics of metabolic syndrome are different in PA compared to EH, as high fasting glucose is more frequent in the former condition.
Zavatta, Guido +5 more
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Acatalasemia and type 2 diabetes mellitus
Orvosi Hetilap, 2015The catalase enzyme decomposes the toxic concentrations of hydrogen peroxide into oxygen and water. Hydrogen peroxide is a highly reactive small molecule and its excessive concentration may cause significant damages to proteins, deoxyribonucleic acid, ribonucleic acid and lipids. Acatalasemia refers to inherited deficiency of the catalase enzyme.
László, Góth +2 more
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Type 2 Diabetes Mellitus in Youth
The Journal of School Nursing, 2003In the United States, the incidence of type 2 diabetes mellitus (DM) in children and adolescents has been increasing at an alarming rate. Early recognition and intervention can delay the onset of type 2 DM and prevent the long-term complications. School nurses have an essential role in implementing the American Diabetes Association (ADA) recommended ...
Jill L, Quarry-Horn +2 more
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Nursing Clinics of North America, 2006
Type 2 diabetes mellitus (T2DM) is a heterogeneous group of metabolic diseases resulting from defects in insulin secretion, insulin action, or both. It comprises most diagnosed cases of diabetes and disproportionately affects minorities. This article describes the classification of diabetes mellitus; defines the metabolic syndrome; and discusses the ...
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Type 2 diabetes mellitus (T2DM) is a heterogeneous group of metabolic diseases resulting from defects in insulin secretion, insulin action, or both. It comprises most diagnosed cases of diabetes and disproportionately affects minorities. This article describes the classification of diabetes mellitus; defines the metabolic syndrome; and discusses the ...
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Pathogenesis of type 2 diabetes mellitus
Medical Clinics of North America, 2004This article provides an overview of the pathogenesis of type 2 diabetes mellitus. Discussion begins by describing normal glucose homeostasis and ingestion of a typical meal and then discusses glucose homeostasis in diabetes. Topics covered include insulin secretion in type 2 diabetes mellitus and insulin resistance, the site of insulin resistance, the
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Pharmacotherapy of Type 2 Diabetes Mellitus
The Annals of Pharmacotherapy, 2000OBJECTIVE: To review the drug treatments and some of the popular, nontraditional remedies now available for type 2 diabetes mellitus, as well as selected investigational agents; to describe each medication's place in the overall approach to treatment. DATA SOURCES: English-language journals, abstracts, review articles, and newspaper accounts.
M S, Rendell, W R, Kirchain
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Liraglutide for type 2 diabetes mellitus
Expert Opinion on Biological Therapy, 2011Prevalence of type 2 diabetes mellitus (T2DM) is increasing. Management of this condition and minimizing the cardiovascular risks associated with it poses a significant burden on healthcare resources across the world. Currently available therapeutic agents are effective in glycemic management; however, the majority of these are associated with ...
Kela, R, Khunti, K, Davies, MJ
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