Results 41 to 50 of about 536,995 (305)

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Perbedaan Kadar Asam Urat pada Penderita Hipertensi dengan Diabetes Melitus Tipe 2 dan tanpa Diabetes Melitus Tipe 2 di Rumah Sakit Umum Daerah Dr. Sayidiman Magetan [PDF]

open access: yes, 2016
Background: The increasing levels of uric acid plays an important role in the morbidity of patients with hypertension. DM is a common comorbid hypertensive patients.
MAULANA, YUDRIK
core  

The impact of type 2 diabetes and Microalbuminuria on future cardiovascular events in patients with clinically manifest vascular disease from the Second Manifestations of ARTerial Disease (SMART) study [PDF]

open access: yes, 2008
Aims Type 2 diabetes mellitus and microalbuminuria are important risk factors for cardiovascular disease (CVD). Whether these two complications are important and independent risk factors for future CVD events in a high-risk population with clinically ...
Algra, A.   +3 more
core   +3 more sources

Simvastatin Use in Patients with Type 2 Diabetes Mellitus: The Effects on Oxidative Stress

open access: yesOman Medical Journal, 2015
Objectives: Studies have shown that people with type 2 diabetes mellitus (T2DM)may develop atherosclerosis due to the disturbance in oxidative control and progressive dyslipidemia.
Mohammad A. Abdelhussein   +3 more
doaj   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Differences Characteristics Patients Diabetes Mellitus Type 2 with and Without Coronary Heart Disease [PDF]

open access: yes, 2017
Diabetes mellitus is the third highest Non-Communicable Diseases (NCDs), which causes death in Indonesia.The incidence of coronary heart disease in diabetes mellitus is high, 65% of people with diabetes mellitus die due to coronary heart disease and ...
Aquarista, N. C. (Nindara)
core   +3 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Preventing Type 2 Diabetes Mellitus [PDF]

open access: yesThe Journal of the American Board of Family Medicine, 2005
Type 2 diabetes is a serious, costly, and increasingly common disease. Several conditions commonly seen in family medicine settings confer increased risk of developing diabetes. Among these conditions are impaired glucose tolerance, impaired fasting glucose, obesity, gestational diabetes, hypertension, hyperlipidemia, and menopause. We here present the
Charlton Wilson, Jeff Curtis
openaire   +2 more sources

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao   +34 more
wiley   +1 more source

Perbedaan Kadar Trigliserida Pada Penderita Diabetes Melitus Tipe 2 Dengan Hipertensi Dan Tanpa Hipertensi Di RSUD Moewardi [PDF]

open access: yes, 2015
Background: Hypertension is common in patients with diabetes mellitus. Hypertension also increases the risk of cardiovascular disease in diabetes mellitus. High triglyserides level was a sign of dislipidemia. Diabetes mellitus and hypertension accompined
, dr. Listiana Masyita Dewi, M.Sc   +2 more
core  

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