Results 41 to 50 of about 1,598,216 (309)

Type 2 diabetes mellitus and bone [PDF]

open access: yesJournal of Internal Medicine, 2018
AbstractType 2 diabetes (T2DM) is a rapidly growing public health problem. It is associated with an increased risk of fracture, particularly of the hip, despite normal or high bone mineral density. Longer duration of disease and poor glycaemic control are both associated with higher fracture risk. The factors underlying increased fracture risk have not
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Simvastatin Use in Patients with Type 2 Diabetes Mellitus: The Effects on Oxidative Stress

open access: yesOman Medical Journal, 2015
Objectives: Studies have shown that people with type 2 diabetes mellitus (T2DM)may develop atherosclerosis due to the disturbance in oxidative control and progressive dyslipidemia.
Mohammad A. Abdelhussein   +3 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Risk Factors of Diabetes Mellitus in Rural Puducherry [PDF]

open access: yes, 2012
Purpose: Prevalence of type 2 diabetes is increasing in India. Rural area constitutes 80% of India. Hence it is essential to understand the epidemiology for appropriate interventions.
Das, AK   +3 more
core   +1 more source

Ethnic differences in Glycaemic control in people with type 2 diabetes mellitus living in Scotland [PDF]

open access: yes, 2013
Background and Aims: Previous studies have investigated the association between ethnicity and processes of care and intermediate outcomes of diabetes, but there are limited population-based studies available.
A Verma   +31 more
core   +4 more sources

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer   +3 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Perbedaan Kadar Asam Urat pada Penderita Hipertensi dengan Diabetes Melitus Tipe 2 dan tanpa Diabetes Melitus Tipe 2 di Rumah Sakit Umum Daerah Dr. Sayidiman Magetan [PDF]

open access: yes, 2016
Background: The increasing levels of uric acid plays an important role in the morbidity of patients with hypertension. DM is a common comorbid hypertensive patients.
MAULANA, YUDRIK
core  

Differences Characteristics Patients Diabetes Mellitus Type 2 with and Without Coronary Heart Disease [PDF]

open access: yes, 2017
Diabetes mellitus is the third highest Non-Communicable Diseases (NCDs), which causes death in Indonesia.The incidence of coronary heart disease in diabetes mellitus is high, 65% of people with diabetes mellitus die due to coronary heart disease and ...
Aquarista, N. C. (Nindara)
core   +3 more sources

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