Results 71 to 80 of about 4,355 (236)

Restoring Histone Acetylation Accelerates Diabetic Wound Repair by Improving the Spatiotemporal Dynamics of Macrophages

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Butyrate—via epigenetic modulation of the histone core—rebalance dysregulated macrophage function and promotes wound healing under persisting hostile conditions of diabetic mice. Additionally, butyrate harmonizes macrophage interactions with keratinocytes and fibroblasts as well as breaks the vicious cycle of inflammation in chronic wounds by restoring
Karmveer Singh, Albert Kallon Koroma, Rajeev Kumar Pandey, Yongfang Wang, Jinnan Cheng, Philipp Haas, Mahyar Aghapour, Linda Krug, Adelheid Hainzl, Meinhard Wlaschek, Pallab Maity, Karin Scharffetter‐Kochanek   +11 more
wiley   +1 more source

Diabetic complications and their implications on health care in Asia. [PDF]

, 2000
Diabetes mellitus is a growing health problem in the Asia-Pacific region. The acute and chronic complications of diabetes mellitus are major causes of hospital admissions, blindness, renal failure, amputations, stroke, and coronary heart disease in this ...
Lam, KS, Leung, GM
core  

CSF markers of vascular injury correlate with tau and cognitive decline in early Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION Cerebrovascular injury is common in Alzheimer's disease (AD), but its timing in relation to Aβ and tau pathology and cognitive decline remains unclear. METHODS We measured baseline vascular marker levels in cerebrospinal fluid (CSF) and serum from 75 Alzheimer's Disease Neuroimaging Initiative (ADNI) study participants, stratified
J. Scott Miners, Gargi Roy, Seth Love, and for the Alzheimer's Disease Neuroimaging Initiative   +3 more
wiley   +1 more source

Caso para diagnóstico? Case for diagnosis?

Anais Brasileiros de Dermatologia, 2008
Os autores relatam caso clínico de paciente do sexo masculino, diabético do tipo II insulinodependente, que apresentava lesões eritêmato-acastanhadas no abdômen e nas coxas, com ligeira atrofia assintomática.
Lorivaldo Minelli, Airton dos Santos Gon, Rodrigo Almeida de Medeiros   +2 more
doaj   +1 more source

Omentin-1 and diabetic retinopathy in type 2 diabetic patients [PDF]

, 2019
Background: Diabetic retinopathy (DR) is one of the most common and serious micro vascular complication affecting type 2 diabetic patients.The literature on adipokines as a possible mechanism in the pathogenesis of DR is contradictory.We are in need for ...
Elgouhary, Sameh Mohamed, Korany, Mohamed Abdelraouf, Sonbol, Ahmed   +2 more
core   +2 more sources

White matter hyperintensity modulates the amyloid‐tau‐cognition association and anti‐amyloid treatment efficacy in asymptomatic older adults

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION White matter hyperintensities (WMH), a key imaging biomarker of small vessel injury, may play a complex role in Alzheimer's disease (AD). We hypothesize that WMH not only directly contributes to cognitive decline but also moderates the relationship among AD pathology, treatment, and cognitive decline.
Zixuan Lin, Yiwen Hong, Yizhe Hu, Qian Xiao, Shin‐Lei Peng, Dan Wu, Tengfei Guo, Dengrong Jiang   +7 more
wiley   +1 more source

Parkinson's Disease: The Epidemiology, Risk Factors, Molecular Pathogenesis, Prevention, and Therapy

MedComm, Volume 6, Issue 12, December 2025.
This graphical abstract summarizes the major components of this review on Parkinson's disease, including epidemiological trends, risk factor classification, peripheral and molecular pathogenesis, and both preventive and therapeutic strategies. The framework reflects the multidimensional organization of the text, covering disease burden, mechanistic ...
Xue‐Yao Guo, Dong‐Yan Song, Ming‐Yang Wu, Jing‐Qi Zhang, Jia‐Yi Li, Lin Yuan   +5 more
wiley   +1 more source

The Possible Role of Tumor Necrosis Factor-α in Diabetic Polyneuropathy [PDF]

, 2003
In this review, the authors provide evidences that imply the role of tumor necrosis factor-α (TNF-α) in the pathogenesis of diabetic complications, especially diabetic polyneuropathy.
Satoh, Jo, Toyota, Takayoshi, Yagihashi, Soroku   +2 more
core   +3 more sources

Endoplasmic Reticulum Stress: A Novel Target for the Prevention and Treatment of Hypertension and Its Related Diseases

Journal of Cellular and Molecular Medicine, Volume 29, Issue 23, December 2025.
ABSTRACT Endoplasmic reticulum stress (ERS) emerges as a critical pathophysiological nexus in hypertension and related cardiovascular diseases. Chronic ERS activation via the IRE1α‐XBP1, ATF6, and PERK pathways drives vascular endothelial dysfunction (reduced NO bioavailability, increased ET‐1), renin‐angiotensin system (RAS) hyperactivation ...
Xin Ma, Fei Si, Jie Ma, Chuyan Feng, Yingdong Wang, Luosha Wang, Jing Yu   +6 more
wiley   +1 more source

Analysing prevalence and morbidity of diabetes and its consequences in the population of Chernivtsi region during 2014-2016 [PDF]

, 2017
Diabetes mellitus (DM) in all its forms is a heavy social and economic burden for any country in the world, regardless of us income. The paper analyzes the prevalence and incidence of diabetes and its consequences in the population of Ukraine and the ...
Bilous, I.I., Chornenka, Zh.A., Pavlovych, L.B.   +2 more
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