Results 71 to 80 of about 616,481 (209)

Association of residential neighborhood disadvantage with amyloid PET positivity among cognitively impaired individuals

open access: yesAlzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 1, March 2026.
Abstract INTRODUCTION Relationships between Alzheimer's disease neuropathology, residential neighborhood, and cognitive impairment remain incompletely understood. METHODS We examined whether residence within a disadvantaged neighborhood was associated with amyloid positron emission tomography (PET) positivity.
Charles C. Windon   +22 more
wiley   +1 more source

Müller Glial Kir4.1 Channel Dysfunction in APOE4‐KI Model of Alzheimer's Disease

open access: yesGlia, Volume 74, Issue 3, March 2026.
APOE4 impairs Müller cell health by reducing Kir4.1 expression and buffering. APOE4 causes mitochondrial dysfunction with decreased ΔΨm and increased ROS. MitoQ restores Kir4.1 expression and reduces ROS in APOE4‐transfected cells. ABSTRACT Alzheimer's disease (AD), particularly late‐onset AD (LOAD), affects millions worldwide, with the apolipoprotein ...
Surabhi D. Abhyankar   +8 more
wiley   +1 more source

Assessment of endothelial function and arterial rigidity in patients with type 1 diabetes at different stages of diabetic nephropathy

open access: yesСахарный диабет, 2011
Aim. Assessment of vascular stiffness and endothelial function in patients with type 1 diabetes at different stages of diabetic nephropathy and without it. Materials and methods.
Evgenia Pavlovna Kosobyan   +4 more
doaj   +1 more source

Diabetic complications and their implications on health care in Asia. [PDF]

open access: yes, 2000
Diabetes mellitus is a growing health problem in the Asia-Pacific region. The acute and chronic complications of diabetes mellitus are major causes of hospital admissions, blindness, renal failure, amputations, stroke, and coronary heart disease in this ...
Lam, KS, Leung, GM
core  

Association between preeclampsia and reversible cerebral vasoconstriction syndrome: A case‐control study

open access: yesPregnancy, Volume 2, Issue 2, March 2026.
Abstract Background and objectives Pregnancy‐related reversible cerebral vasoconstriction syndrome (RCVS) has higher rates of intracerebral complications and mortality compared to non‐pregnant RCVS. Case reports suggest preeclampsia‐eclampsia as an important risk factor; however, data are limited regarding this association.
Srinath Ramaswamy   +7 more
wiley   +1 more source

Omentin-1 and diabetic retinopathy in type 2 diabetic patients [PDF]

open access: yes, 2019
Background: Diabetic retinopathy (DR) is one of the most common and serious micro vascular complication affecting type 2 diabetic patients.The literature on adipokines as a possible mechanism in the pathogenesis of DR is contradictory.We are in need for ...
Elgouhary, Sameh Mohamed   +2 more
core   +2 more sources

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner   +8 more
wiley   +1 more source

Caso para diagnóstico? Case for diagnosis?

open access: yesAnais Brasileiros de Dermatologia, 2008
Os autores relatam caso clínico de paciente do sexo masculino, diabético do tipo II insulinodependente, que apresentava lesões eritêmato-acastanhadas no abdômen e nas coxas, com ligeira atrofia assintomática.
Lorivaldo Minelli   +2 more
doaj   +1 more source

Plasma and neuroimaging biomarkers of small vessel disease and Alzheimer's disease in a diverse cohort: MESA

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Little is known about how Alzheimer's disease (AD) plasma biomarkers relate to cerebral small vessel disease (cSVD) neuroimaging biomarkers. METHODS The study involved 251 Wake Forest Multi‐Ethnic Study of Atherosclerosis (MESA) Exam 6 participants with plasma AD biomarkers, magnetic resonance imaging, amyloid positron emission ...
Samuel N. Lockhart   +22 more
wiley   +1 more source

The Possible Role of Tumor Necrosis Factor-α in Diabetic Polyneuropathy [PDF]

open access: yes, 2003
In this review, the authors provide evidences that imply the role of tumor necrosis factor-α (TNF-α) in the pathogenesis of diabetic complications, especially diabetic polyneuropathy.
Satoh, Jo   +2 more
core   +3 more sources

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