Results 51 to 60 of about 308,698 (194)
В статье изложены особенности поражений сосудов и патогенетические механизмы сосудистых нарушений при сахарном диабете, а также значение изучения сосудистого русла больших слюнных желез крысы в норме и на фоне экспериментального сахарного диабета.
openaire +3 more sources
Gestational diabetes alters the adipose–mammary gland axis, changing human milk composition—notably reducing adiponectin and dysregulating miR‐148a, miR‐30b, let‐7a, and let‐7d, which target ADIPOQ, LEP, and RETN and are enriched in glucose homeostasis/insulin resistance pathways.
Zhijun Zhang +8 more
wiley +1 more source
Immunological and genetic factors associated with type 1 diabetic nephropathy [PDF]
Väitöskirjaei tietoa saavutettavuudesta unknown ...
Korpinen, Eija
core
Aim. Assessment of vascular stiffness and endothelial function in patients with type 1 diabetes at different stages of diabetic nephropathy and without it. Materials and methods.
Evgenia Pavlovna Kosobyan +4 more
doaj +1 more source
Ubiquitous cell‐associated, cytoplasmic, synaptic and extracellular matrix HS‐proteoglycans are multifunctional regulators of tissue form and function. HS‐proteoglycans have diverse functions as growth factor co‐receptors in cell proliferation, differentiation, tissue development, mechanical stabilization, synaptogenesis, synaptic plasticity, and ...
James Melrose
wiley +1 more source
Circadian rhythms and chronotherapy in Alzheimer's disease: Mechanisms and therapeutic implications
Circadian dysregulation contributes to Alzheimer's disease through sleep disruption, clock‐gene dysfunction, neuroinflammation, impaired proteostasis, and metabolic imbalance. These alterations promote cognitive decline and disease progression, while circadian biomarkers and chronotherapeutic interventions offer opportunities for precision diagnosis ...
Bivek Singh +2 more
wiley +1 more source
Heart disease in infants of diabetic mothers [PDF]
Congenital anomalies occur more commonly in infants born to diabetic mothers, and cardiac defects predominate. Although respiratory problems are also frequently found in those infants, they need to be differentiated from cardiovascular problems that ...
Narchi, Hassib, Kulaylat, N.
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Caso para diagnóstico? Case for diagnosis?
Os autores relatam caso clínico de paciente do sexo masculino, diabético do tipo II insulinodependente, que apresentava lesões eritêmato-acastanhadas no abdômen e nas coxas, com ligeira atrofia assintomática.
Lorivaldo Minelli +2 more
doaj +1 more source
New perspectives on VEGF signalling in Alzheimer's disease
Emery et al. bring together findings from recent multi‐omic studies, including single‐cell mRNA analysis of human post‐mortem brain tissue, and proteomic analysis of matched CSF and blood samples in large clinical studies. The authors present evidence of the involvement of altered VEGF signalling in vascular and immune dysfunction and neurodegeneration
Cherelle E. G. Emery +2 more
wiley +1 more source
Combating ageing beyond the cell: Emerging roles of extracellular proteostasis
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh +7 more
wiley +1 more source

