Results 111 to 120 of about 600,025 (282)
Atherosclerosis-predominant vasculopathy is a common complication of diabetes with high morbidity and high mortality, which is ruining the patient's daily life.
Hong Gao+7 more
doaj +1 more source
Unraveling sex differences in Alzheimer's disease and related endophenotypes with brain proteomes
Abstract INTRODUCTION Sex differences exist in Alzheimer's disease (AD), but the underlying mechanisms remain unclear. METHODS We examined brain proteomes profiled from the dorsolateral prefrontal cortex of 770 donors (66.2% female). RESULTS Proteome‐wide differential expression analysis in males and females jointly identified many significant proteins
Zhen Mei+5 more
wiley +1 more source
Background Diabetic nephropathy is a microvascular diabetic complication secondary to longstanding diabetes due to angiopathy of capillaries in glomeruli now recognized as long standing chronic inflammatory disease.
Pooja A Baviskar+2 more
doaj +2 more sources
Differential gene expression of NADPH oxidase (p22phox) and hemoxygenase-1 in patients with Type 2 diabetes and microangiopathy [PDF]
Aims: While the downstream effects of increased reactive oxygen species (ROS) in the pathogenesis of diabetes were well studied, only a few studies have explored the cellular sources of ROS.
Adaikalakoteswari, A+3 more
core +1 more source
Abstract INTRODUCTION Retinal and choroidal vascular changes have been proposed as a non‐invasive central nervous system (CNS) proxy for clinical trials in Alzheimer's disease (AD). However, their role in Down syndrome (DS), the largest genetically predisposed group for AD, remains unclear.
Jamie Mitchell+10 more
wiley +1 more source
Treatment of diabetic angiopathy of the lower limb in the conditions of a specialized department. [PDF]
MAZAHIR MURSAL MURSALOV
openalex +1 more source
Діагностична цінність інфрачервоної термометрії у хворих на цукровий діабет із маніфестними ангіопатіями ніг [PDF]
У статті вивчено можливості застосування інфрачервоної термометрії для складання карти температур у 16 хворих на цукровий діабет із хірургічними ускладненнями з боку нижніх кінцівок.
Коновчук, Віктор Миколайович+1 more
core
Cerebral Small Vessel Disease: Targeting Oxidative Stress as a Novel Therapeutic Strategy? [PDF]
Cerebral small vessel disease (SVD) is a major contributor to stroke, and a leading cause of cognitive impairment and dementia. Despite the devastating effects of cerebral SVD, the pathogenesis of cerebral SVD is still not completely understood. Moreover,
Alyson A. Miller, T. Michael De Silva
core +2 more sources
Abstract INTRODUCTION Oxidative stress (OS) is implicated in dementia. While elevated peripheral OS biomarkers were observed in vascular mild cognitive impairment (vMCI), the role of central antioxidants remains unclear. We assessed levels of the major brain antioxidant glutathione (GSH) in vMCI compared to cognitively normal coronary artery disease ...
Jinghan Jenny Chen+15 more
wiley +1 more source