Gene therapy targeting inflammatory pericytes corrects angiopathy during diabetic wound healing [PDF]
Wound healing is impaired in the diabetic status, largely attributable to diabetes-associated angiopathy. Pericytes play critical roles in the stabilization of the formed vessels.
Wenxv Jin+3 more
doaj +3 more sources
Combined physical therapy for diabetic angiopathy
Background. The problem of diabetic angiopathy is characteristic of countries even with a high level of development of medicine. The high frequency of complications of diabetes with high biological and social significance determines the need for their correction. The purpose of the work was to increase the effectiveness of rehabilitation treatment for
Denis V. Frolov+3 more
semanticscholar +4 more sources
Redox Status of β2GPI in Different Stages of Diabetic Angiopathy. [PDF]
We explored the redox status of beta 2 glycoprotein I (β 2GPI) in different stages of diabetic angiopathy. Type 2 diabetes mellitus (T2DM) had a significantly lower proportion of reduced β 2GPI as compared to healthy controls (p < 0.05).
Ma J, Zhang JY, Liu Y, Yu DM, Yu P.
europepmc +4 more sources
Transcriptional profiling of mouse cavernous pericytes under high-glucose conditions: Implications for diabetic angiopathy. [PDF]
Purpose Penile erection requires integrative interactions between vascular endothelial cells, pericytes, smooth muscle cells, and autonomic nerves. Furthermore, the importance of the role played by pericytes in the pathogenesis of angiopathy has only ...
Yin GN+8 more
europepmc +3 more sources
Protective Effects and Mechanisms of Vaccarin on Vascular Endothelial Dysfunction in Diabetic Angiopathy. [PDF]
Cardiovascular complications are a major leading cause of mortality in patients suffering from type 2 diabetes mellitus (T2DM). Vascular endothelial dysfunction is a core pathophysiological event in the early stage of T2DM and eventually leads to ...
Xu F+13 more
europepmc +4 more sources
Evaluation of the Occlusive Arterial Disease and Diabetic Angiopathy Treatment Effects by Hyperbaric Oxygenation. [PDF]
Introduction: One of the most severe complications of atherosclerosis is arterial occlusive disease (AOD) and with diabetic angiopathy (DA), is a common chronic problem in clinical practice worldwide.
Begić A, Dilić M.
europepmc +4 more sources
Peroxynitrite-induced Nitration of Cyclooxygenase-2 and Inducible Nitric Oxide Synthase Promotes Their Binding in Diabetic Angiopathy [PDF]
Cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) play crucial roles in diabetic angiopathy. In vivo, however, the following facts remain unknown: whether COX-2 and iNOS bind, how peroxynitrite-induced nitration of COX-2 and iNOS ...
Yanning Li+5 more
semanticscholar +2 more sources
The photoplethysmography potential for the early diagnosis of diabetic angiopathy of the lower limbs
Background. In most cases of diabetes mellitus (DM), a complication in the form of diabetic angiopathy of the lower limbs is diagnosed rather late when clinical manifestations of vascular pathology appear. Wellness activities at this stage are palliative,
L.V. Vorobjov
doaj +2 more sources
Trial of repeated low-dose aspirin in diabetic angiopathy. [PDF]
We compared the ability of aspirin to suppress platelet aggregation and thromboxane synthesis in ten normal subjects and ten patients with diabetic angiopathy and high rate of entry of new platelets into the circulation. When single doses of 100 to 1,000
G. DiMinno+3 more
semanticscholar +2 more sources
Effects of irbesartan on intracellular antioxidant enzyme expression and activity in adolescents and young adults with early diabetic angiopathy. [PDF]
OBJECTIVE Defective intracellular antioxidant enzyme production (IAP) has been demonstrated in adults with diabetic nephropathy. The objective of this study was to evaluate the effects of irbesartan, an angiotensin II receptor antagonist, on IAP in ...
F. Chiarelli+7 more
semanticscholar +2 more sources