Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease [PDF]
Because regional blood flow increases in association with the increased metabolic demand generated by localised increases in neural activity, functional imaging researchers often assume that changes in blood flow are an accurate read-out of changes in ...
Attwell, D., Hall, C.N., Hamilton, N.B.
core +3 more sources
Nitric Oxide Bioavailability and Its Potential Relevance to the Variation in Susceptibility to the Renal and Vascular Complications in Patients With Type 2 Diabetes [PDF]
OBJECTIVE—We compared the renal and systemic vascular (renovascular) response to a reduction of bioavailable nitric oxide (NO) in type 2 diabetic patients without nephropathy and of African and Caucasian heritage.
Barron, J +4 more
core +2 more sources
Background: Diabetes is a long-term condition that can be treated and controlled but do not yet have a cure; it could be induced by inflammation and the goal of managing it is to prevent additional co-morbidities and reduce glycemic fluctuations.
Martin C. Nwadiugwu
doaj +1 more source
Clinical studies of glucose variability and hypoglycemia in adult patients with type 1 diabetes [PDF]
Diabetes mellitus type 1 is a condition characterized by elevated blood glucose values due to impaired insulin production. This condition is associated with increased morbidity from microand macrovascular complications.
Bragd, Joakim
core +1 more source
The vascular complications occurring in diabetes mellitus are reviewed. In addition to the long recognised involvement of large vessels by atheroma and Monckeberg's sclerosis, the more recently described microangiopathy affecting arterioles, venules and, in particular, capillaries is also described.
openaire +6 more sources
Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats [PDF]
Background: Metabolic syndrome (coexisting visceral obesity, dyslipidemia, hyperglycemia, and hypertension) is a prominent risk factor for cardiovascular morbidity and mortality, however, its effect on cardiac gene expression pattern is unclear ...
Csonka, Csaba +10 more
core +3 more sources
Empagliflozin reduces vascular damage and cognitive impairment in a mixed murine model of Alzheimer's disease and type 2 diabetes [PDF]
Background Both Alzheimer's disease (AD) and type 2 diabetes (T2D) share common pathological features including inflammation, insulin signaling alterations, or vascular damage.
Alves-Martinez, Pilar +8 more
core +1 more source
Quality of life in Type 1 (insulin-dependent) diabetic patients prior to and after pancreas and kidney transplantation in relation to organ function [PDF]
Improvement of the quality of life in Type 1 (insulin-dependent) diabetic patients with severe late complications is one of the main goals of pancreas and/or kidney grafting. To assess the influences of these treatment modalities on the different aspects
A Kaplan De-Nour +33 more
core +1 more source
The article contains research materials relating to issues associated with the development of vascular com-plications in diabetic patients. The article examines the main factors and mechanisms of development of diabetic angiopathy.
Tatiana Petrovna Bondar +3 more
doaj
Equity in healthcare: status, barriers, and challenges [PDF]
Global health provides a challenge for primary care and general practice which will become increasingly important in the future as the prevalence of multimorbidity increases. There is increasing likelihood of survival from acute illnesses and increase an
Al-Arafah, Assad +20 more
core +1 more source

