Results 61 to 70 of about 9,144 (265)

Low Red Blood Cell Vitamin C Concentrations Induce Red Blood Cell Fragility: A Link to Diabetes Via Glucose, Glucose Transporters, and Dehydroascorbic Acid

EBioMedicine, 2015
Strategies to prevent diabetic microvascular angiopathy focus on the vascular endothelium. Because red blood cells (RBCs) are less deformable in diabetes, we explored an original concept linking decreased RBC deformability to RBC ascorbate and ...
Hongbin Tu, Hongyan Li, Yu Wang, Mahtab Niyyati, Yaohui Wang, Jonathan Leshin, Mark Levine   +6 more
doaj   +1 more source

Revealing the Angiopathy of Lacrimal Gland Lesion in Type 2 Diabetes

Frontiers in Physiology, 2021
For a better understanding of diabetic angiopathy (DA), the potential biomarkers in lacrimal DA and its potential mechanism, we evaluated the morphological and hemodynamic alterations of lacrimal glands (LGs) in patients with type 2 diabetes and healthy ...
Junfa Xue, Junfa Xue, Bin Zhang, Shengqian Dou, Qingjun Zhou, Min Ding, Mingming Zhou, Huifeng Wang, Huifeng Wang, Yanling Dong, Dongfang Li, Dongfang Li, Lixin Xie   +12 more
doaj   +1 more source

Lower risk of heart failure and death in patients initiated on sodium-glucose cotransporter-2 inhibitors versus other glucose-lowering drugs:The CVD-REAL study (Comparative Effectiveness of Cardiovascular Outcomes in New Users of Sodium-Glucose Cotransporter-2 Inhibitors) [PDF]

, 2017
Background: Reduction in cardiovascular death and hospitalization for heart failure (HHF) was recently reported with the sodium-glucose cotransporter-2 inhibitor (SGLT-2i) empagliflozin in patients with type 2 diabetes mellitus ...
Arya, Niki, Birkeland, Kåre I., Bodegård, Johan, Cavender, Matthew A., Fenici, Peter, Fu, Alex Z., Hammar, Niklas, Holl, Reinhard W., Jørgensen, Marit Eika, Khunti, Kamlesh, Kosiborod, Mikhail, Norhammar, Anna, Thuresson, Marcus, Wilding, John P.   +13 more
core   +2 more sources

Applying the Canadian Head CT Criteria to Older Adults Seen in the Emergency Department After a Fall

Journal of the American Geriatrics Society, EarlyView.
Prevalence of intracranial bleeding in adults based on the CCTHR criteria. ABSTRACT Background The Canadian CT Head Rule (CCTHR) is validated in adults who hit their head and experience loss of consciousness, amnesia, or disorientation. There is less evidence to guide brain imaging when the fall history is unclear.
Geoff Kerr, Allie Chown, Mathew Mercuri, Natasha Clayton, Éric Mercier, Judy Morris, Rebecca Jeanmonod, Debra Eagles, Catherine Varner, David Barbic, Sameer Parpia, Ian M. Buchanan, Mariyam Ali, Yoan K. Kagoma, Ashkan Shoamanesh, Paul Engels, Sunjay Sharma, Andrew Worster, Shelley McLeod, Marcel Émond, Ian Stiell, Alexandra Papaioannou, Kerstin de Wit   +22 more
wiley   +1 more source

Relative influence of sulodexide and pentoxifylline to the skin microcirculation in the experimental streptozotocin-induced diabetic angiopathy

Journal of Education, Health and Sport, 2015
Chekhlova O V, Rosha L G. Дослідження порівняльного впливу сулодексиду та пентоксифіліну на стан судин мікроциркуляторного русла шкіри за умов експериментальної стрептозотоцин-індукованої діабетичної ангіопатії = Relative influence of sulodexide and ...
O. V. Chekhlova, L. G. Rosha
doaj   +2 more sources

Novel anti-obesity quercetin-derived Q2 prevents metabolic disorders in rats fed with high-fat diet [PDF]

, 2018
Objective: Obesity is often accompanied by an increased morbidity and mortality due to an increase of the cardiovascular disease risk factors, diabetes mellitus and dyslipidemia. Research is constantly working on protective molecules against obesity.
Albano, Luigi, Amelio, D, Angelone, Tommaso, Granieri, Mc, Macchia, Pe, Nettore, Ic, Rocca, C, Sinicropi, S, Ungaro, Paola   +8 more
core   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, Andrew F. James, Svetlana Mastitskaya   +2 more
wiley   +1 more source

Targeting Ferroptosis: New Insights and Therapeutic Advances in MAFLD Complicating T2DM

Frontiers in Bioscience-Landmark
Epidemiological data show a strong connection between type 2 diabetes mellitus (T2DM) and metabolic-associated fatty liver disease (MAFLD). In recent years, the prevalence of both conditions has been rising simultaneously.
Fang Yao, Gaochao Wang, Fan Ning, Yanbo Shi   +3 more
doaj   +1 more source

KIDNEY TRANSPLANTATION AND DISTAL SPLENORENAL VENOUS ANASTOMOSIS IN THE TREATMENT OF DIABETIC NEPHROPATHY

Вестник трансплантологии и искусственных органов, 2010
A cadaveric kidney transplantation (KT) combined with distal venous splenorenal anastomosis is suggested as the surgical method for type 1 diabetes treatment (Shraer T.I.).
T. A. Piminova, A. A. Salmayer, T. I. Shraer, A. M. Putincev, S. A. Syomina, N. K. Galcovsky, V. A. Lucenko   +6 more
doaj   +1 more source

Differential gene expression of NADPH oxidase (p22phox) and hemoxygenase-1 in patients with Type 2 diabetes and microangiopathy [PDF]

, 2006
Aims: While the downstream effects of increased reactive oxygen species (ROS) in the pathogenesis of diabetes were well studied, only a few studies have explored the cellular sources of ROS.
Adaikalakoteswari, A, Balasubramanyam, M, Mohan, V, Rema, M   +3 more
core   +1 more source