Results 81 to 90 of about 9,144 (265)

The Effect of Dietary and Exercise Self-Management Support Program on Dietary Behavior Exercise Behavior and Clinical Outcomes in Muslim Patients with Poorly Controlled Type 2 DM in a Community Setting in Indonesia [PDF]

open access: yes, 2015
Purpose: The objective of this study was to examine the effect of dietary and exercise self-management support program on the dietary behavior, exercise behavior, and clinical outcomes of Muslim patients with poorly controlled type 2 DM in Indonesia ...
Chinnawong, T. (Tippamas)   +2 more
core   +1 more source

White matter hyperintensity modulates the amyloid‐tau‐cognition association and anti‐amyloid treatment efficacy in asymptomatic older adults

open access: yesAlzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION White matter hyperintensities (WMH), a key imaging biomarker of small vessel injury, may play a complex role in Alzheimer's disease (AD). We hypothesize that WMH not only directly contributes to cognitive decline but also moderates the relationship among AD pathology, treatment, and cognitive decline.
Zixuan Lin   +7 more
wiley   +1 more source

Prevention of Protein Glycation by Natural Compounds [PDF]

open access: yes, 2015
Non-enzymatic protein glycosylation (glycation) contributes to many diseases and aging of organisms. It can be expected that inhibition of glycation may prolong the lifespan.
Bartosz, Grzegorz   +1 more
core   +2 more sources

Apolipoprotein E ε4 homozygosity exacerbates retinal and cerebral microvascular dysfunction in Alzheimer's disease: A mediation analysis of vascular contributions to cognitive decline

open access: yesAlzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION Apolipoprotein E (APOE) ε4 is the strongest genetic risk factor for Alzheimer's disease (AD), with homozygous carriers (ε4/ε4) experiencing accelerated cognitive decline. While its role in amyloid and tau pathology is established, its impact on retinal and cerebral microvasculature remains underexplored. METHODS A total of 107 AD (
Yuntao Liu   +13 more
wiley   +1 more source

Diabetic Foot and Fungal Infections: Etiology and Management from a Dermatologic Perspective

open access: yesJournal of Fungi
Diabetes Mellitus (DM) is a significant global concern. Many diabetic patients will experience complications due to angiopathy, neuropathy, and immune dysfunction, namely diabetic foot ulcers (DFU) and diabetic foot infections (DFI), which can result in ...
Aditya K. Gupta   +3 more
doaj   +1 more source

Influence of Decreased Thyroid Function on the Clinical Course and Occurrence of Vascular Complications of Diabetes Mellitus Type 2

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2014
The article studies the clinical course and characteristics of vascular complications in patients with diabetes mellitus type 2 on a background of diminished thyroid function. We analyzed the prevalence and severity of diabetic retinopathy, angiopathy of
Ye.S. Krutikov   +2 more
doaj   +1 more source

Causal Relationship Between Circulating Omega‐3 Fatty Acid and Cerebral Small Vessel Disease: A Mendelian Randomization Study

open access: yesFood Science &Nutrition, Volume 13, Issue 12, December 2025.
This Mendelian randomization study demonstrated that higher circulating omega‐3 fatty acid levels were causally associated with a modest reduction in risk of cerebral microbleeds (CMB). No significant associations were observed for other CSVD phenotypes, including WMH, LS, and WMPVS.
Yaodan Zhang   +6 more
wiley   +1 more source

The Impact of Green Tea on Blood Fluidity Improvement and Weight Loss [PDF]

open access: yes, 2014
Introduction: Various studies have shown the benefi cial effects of green tea, not only on cardiovascular diseases butalso on type 2 diabetes. Method: In this study, the preparation of green tea water extract has been standardized to (-)-epigalocatechin ...
Darmawati, A. (Asri)   +2 more
core  

Different behaviour of the N-terminal and C-terminal fragment of proatrial natriuretic factor in plasma of healthy subjects as well as of patients with cirrhosis [PDF]

open access: yes, 1990
N-terminal (atrial natriuretic factor (ANF) 1-98) and C-terminal (ANF 99-126) fragments of proatrial natriuretic factor (NTA and CTA, respectively) were determined in plasma of healthy subjects adopting different postures and in patients with cirrhosis ...
Arendt, Rainer M.   +5 more
core   +1 more source

Parkinson's Disease: The Epidemiology, Risk Factors, Molecular Pathogenesis, Prevention, and Therapy

open access: yesMedComm, Volume 6, Issue 12, December 2025.
This graphical abstract summarizes the major components of this review on Parkinson's disease, including epidemiological trends, risk factor classification, peripheral and molecular pathogenesis, and both preventive and therapeutic strategies. The framework reflects the multidimensional organization of the text, covering disease burden, mechanistic ...
Xue‐Yao Guo   +5 more
wiley   +1 more source

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