Results 61 to 70 of about 15,034 (205)

Effects of short‐term tofogliflozin treatment on the insulin secretory capacity of people with type 2 diabetes: A randomized controlled trial, the TOP‐ELM study

Journal of Diabetes Investigation, EarlyView.
Tofogliflozin was compared with metformin in treatment‐naïve people with type 2 diabetes for 4 weeks. Overall insulin secretory capacity did not improve; however, tofogliflozin was associated with an improved disposition index in individuals with poorer baseline glucose tolerance or greater improvement after treatment.
Maiko Miyamoto, Aika Miya, Akinobu Nakamura, Yuka Takahashi, Yuki Yamauchi, Shingo Yanagiya, Takahiro Takase, Mayuko Ono, Kiyohiko Takahashi, Kazufumi Okada, Hiraku Kameda, Kyu Yong Cho, Tatsuya Atsumi, on behalf of TOP‐ELM study group, Maiko Miyamoto, Aika Miya, Akinobu Nakamura, Hiraku Kameda, Kyu Yong Cho, Tatsuya Atsumi, Kazufumi Okada, Rimi Izumihara, Yuki Oe, Takahiro Takase, So Nagai, Akihiro Takahashi, Yuka Takahashi, Yuki Yamauchi, Hiromichi Kijima, Shinji Taneda, Jun Takeuchi, Kei Yokozeki, Saki Kuwabara, Yoshiaki Arimura, Shinichiro Kawata, Tomonori Sekizaki, Yuki Yamauchi, Shingo Yanagiya, Mayuko Ono, Kiyohiko Takahashi   +39 more
wiley   +1 more source

Safety of anagliptin/metformin combination tablets evaluated by non‐inferiority between pre‐ and post‐serum lactic acid levels in Japanese patients with type 2 diabetes and moderate renal impairment (AMELIO STUDY)

Journal of Diabetes Investigation, EarlyView.
To investigate the safety of anagliptin/metformin combination tablets in Japanese patients of type 2 diabetes with moderate renal impairment. This study demonstrates that the fixed‐dose combination of anagliptin and metformin can be used safely in patients with type 2 diabetes complicated by moderate renal dysfunction.
Hiroshi Kajio, Ryotaro Bouchi, Mitsuhisa Komatsu, Masanori Yamazaki, Daisuke Takarabe, Masahide Okamoto, Takahisa Tanaka, Toru Kitazawa, Hisayuki Katsuyama, Yasumichi Mori, Mitsuhiko Noda   +10 more
wiley   +1 more source

Early Use of Fentanyl Increases Risk of Delirium in Patients Transfer to the intensive Care Unit After Cardiac Surgery Immediately: A Target Trial Emulation

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Aim In the post‐operative period of cardiac surgeries, the majority of patients are admitted to the intensive care unit (ICU) for ongoing management, where delirium frequently occurs as a complication. However, the association between various analgesic regimens and the onset of postoperative delirium in ICU patients following cardiac surgery ...
Zhongkai Qu, Weisheng Chen, Xinya Li, Bo Chen, Li Li, Shuna Li, Liying Huang, Ningxia He, Jun Lyu, Zhigang Wang   +9 more
wiley   +1 more source

Blood Glucose and Neurological Status: Dual Predictors of Survival in Diabetic Emergency

Preventive Care in Nursing and Midwifery Journal
Background: Acute diabetic emergencies, including diabetic ketoacidosis (DKA), hyperosmolar hyperglycaemic syndrome (HHS), and hypoglycaemia, require urgent medical intervention.
Lintang Arum Nikentari, Heri Kristianto, Laily Yuliatun, Ali Haedar, Paulus Lucky Tirma Irawan   +4 more
doaj   +1 more source

Diabetic ketoacidosis and hyperglycemic hyperosmolar syndrome after renal transplantation in the United States

BMC Endocrine Disorders, 2003
Background The incidence and risk factors for diabetic ketoacidosis (diabetic ketoacidosis) and hyperglycemic hyperosmolar syndrome (hyperglycemic hyperosmolar syndrome, previously called non-ketotic hyperosmolar coma) have not been reported in a ...
Agodoa Lawrence Y, Bernet Victor J, Abbott Kevin C, Yuan Christina M   +3 more
doaj   +1 more source

Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Acute pancreatitis (AP) is a common clinical inflammatory condition whose severity is closely associated with both local pancreatic injury and systemic complications. Research indicates that gut microbiota dysbiosis and subsequent bacterial translocation can exacerbate disease progression via the gut–pancreas axis, representing a critical ...
Jiawei Chen, Caihan Duan, Keyi Zhang, Jun Liu, Chaoqun Han   +4 more
wiley   +1 more source

Predictors of Readiness to Engage in Advance Care Planning Among Older Adults With Serious Illness: Baseline Findings From the EQUAL ACP Study

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Advance care planning (ACP) supports seriously ill individuals in identifying and communicating their values and preferences for future care. However, disparities in ACP engagement persist, particularly among African American older adults.
Deborah Ejem, Alyssa Platt, Ramona L. Rhodes, Anupama Gangavati, Nadine Barrett, Marie Bakitas, Marisette Hasan, Ronit Elk, Raegan W. Durant, Maren Olsen, Kenisha Bethea, Tammie Quest, Kimberly S. Johnson   +12 more
wiley   +1 more source

Chronic Insomnia and Excess Cannabis Ingestion in an Older Adult—A Clinical Report of Complex Geriatric Care

Journal of the American Geriatrics Society, EarlyView.
Cannabis use in older adults may have a broad range of effects in older adults impacting Mind, Mobility, Medications, Multi‐complexity, and what Matters Most.
Erik Fraunberger, Maia von Maltzahn
wiley   +1 more source

Hyperosmolar Hyperglycemic Non Ketotic Coma and Rhabdomyolysis- An Uncommon Clinical Encounter

Libyan Journal of Medicine, 2009
Rhabdomyolysis is usually attributed to trauma. However there is an association of rhabdomyolysis with hyperosmolar states. Recognition of this association will enable better management of the patient and reduce the burden on the care taker by preventing
Philip C, Jacob J, Gupta S
doaj  

Psychogenic polydipsia in dogs – a review of pathogenesis, diagnosis and treatment

Journal of Small Animal Practice, EarlyView.
Polyuria and polydipsia represent a common clinical presentation in dogs and may result from numerous disorders affecting different body systems. Compulsive water consumption is characteristic of psychogenic polydipsia, a primary polydipsia disorder rooted in neurologic, behavioural or environmental factors.
G. Pavlovsky
wiley   +1 more source