Results 171 to 180 of about 1,058,153 (397)
Okanin Suppresses the Growth of Colorectal Cancer Cells by Targeting at Peroxiredoxin 5
Okanin suppresses colorectal cancer growth by directly targeting PRDX5. This natural compound selectively binds peroxiredoxin 5 (PRDX5), inhibiting its activity and inducing WSB1‐mediated degradation. PRDX5 loss elevates ROS, suppresses GPX4 via SIAH2, and further triggers cell death (apoptosis and ferroptosis).
Ji Zhong Zhao+9 more
wiley +1 more source
HUBUNGAN TINGKAT DEPRESI DENGAN DERAJAT DIABETIC FOOT ULCER PADA PASIEN RAWAT JALAN DI POLIKLINIK ENDOKRIN RSUD DR. ZAINOEL ABIDIN BANDA ACEH [PDF]
ABSTRAKPasien diabetic foot ulcer umumnya mengalami hambatan dalam sosialisasi sehingga mengalami depresi. Depresi dapat menyebabkan supresi sistem imun yang berkaitan dengan derajat ulkus yang ditimbulkan. Tujuan penelitian ini adalah untuk menganalisis
Salfiana Riko
core
Diabetic foot as a complication of diabetes
AdmissionDiabetic foot is a chronic complication of diabetes. Is a shallow or deep skin ulcer. It can occur with both type 1 and type 2 diabetes. Diabetic foot can appear in anyone with diabetes. This condition is associated with all kinds of complications or pathological changes that are a direct result of diabetes.
openaire +4 more sources
MANF in cardiomyocytes interacts with BAX to impede BAX mitochondrial translocation and cytochrome c release, further stabilizing mitochondrial structure and energy supply to relieve myocardial apoptosis and hypertrophy, which indicates MANF as a novel cardioprotective factor to have a promising clinical application for myocardial hypertrophy ...
Dong Wang+13 more
wiley +1 more source
End-Stage Complications of Diabetic Neuropathy: Foot Ulceration [PDF]
Andrew J.M. Boulton
openalex +1 more source
Personalized Medication for Chronic Diseases Using Multimodal Data‐Driven Chain‐of‐Decisions
A MDD‐CoD is proposed for personalized chronic disease medication. The framework simulates clinical chain‐of‐decisions through three linked deep learning tasks, validated on multi‐center datasets (3 hospitals, 4 diseases), demonstrating enhanced generalization and interpretability in cross‐disease applications.
Xiaoli Chu+10 more
wiley +1 more source
The economics of setting up a diabetic foot clinic [PDF]
K. T. Moriarty+3 more
openalex +1 more source