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Strategy for Treatment of Infected Diabetic Foot Ulcers

Accounts of Chemical Research, 2021
ConspectusDiabetic foot ulcers (DFUs) are chronic wounds that develop in 30% of diabetic patients. In DFUs, the normal wound healing process consisting of inflammation, angiogenesis, and extracellular matrix (ECM) remodeling is dysregulated and stalled ...
Mayland Chang
exaly   +2 more sources

Diabetic Foot Ulcers and Their Recurrence

New England Journal of Medicine, 2017
Andrew J M Boulton, Sicco A Bus
exaly   +2 more sources

Global epidemiology of diabetic foot ulceration: a systematic review and meta-analysis

Annals of Medicine, 2017
Pengzi Zhang   +5 more
exaly   +2 more sources

The Diabetic Foot

Orthopedics, 1987
ABSTRACT: Amputation of the lower extremity is more frequent in diabetic patients than in the general population. Causative factors include foot deformities, neuropathy, dysvascularity, infection, and gangrene. A grading and treatment program is outlined for aid in treating the lesions that develop in these feet.
M B, Zlatkin   +3 more
openaire   +4 more sources

Global mortality of diabetic foot ulcer: A systematic review and meta‐analysis of observational studies

Diabetes, obesity and metabolism, 2022
To estimate the long‐term mortality and risk factors in patients with diabetic foot ulcer (DFU).
Lihong Chen   +3 more
semanticscholar   +1 more source

Bone marrow stromal cell‐derived exosomal circular RNA improves diabetic foot ulcer wound healing by activating the nuclear factor erythroid 2‐related factor 2 pathway and inhibiting ferroptosis

Diabetic Medicine, 2022
Diabetic foot ulcer (DFU) remains a serious chronic diabetic complication that can lead to disability. CircRNA‐itchy E3 ubiquitin protein ligase (circ‐ITCH) was observed to be down‐regulated in diabetic retinopathy and diabetic nephropathy, and ...
Juehao Chen   +9 more
semanticscholar   +1 more source

The diabetic foot

Current Problems in Surgery, 2016
A comprehensive program focused on foot-specific patient education, skin and nail care, and protective footwear lowers the incidence of diabetic foot ulcers and lower extremity amputations. Orthopedic or podiatric consultations are warranted for those “at risk” or with foot ulcers.
Richard F, Neville   +3 more
openaire   +4 more sources

The Diabetic Foot

Surgical Clinics of North America, 2007
Lower extremity complications are common in patients with diabetes and include neuropathy, ulceration, infection, and peripheral arterial disease. Foot infections represent the single most common cause of hospitalization and lower extremity amputation in persons with diabetes. Foot ulceration as a result of diabetic peripheral sensory neuropathy, rigid
Charles A, Andersen, Thomas S, Roukis
openaire   +4 more sources

Management of the diabetic foot

Seminars in Vascular Surgery, 2022
The increasing prevalence of diabatic foot ulcers (DFUs) is not only costly, but carries a large mortality burden. In this article, we discuss important traditional concepts in the management of DFUs and elaborate on how new technologies have expanded our ability to treat DFUs effectively.
Tiffany R. Bellomo   +6 more
openaire   +2 more sources

The Diabetic Foot

Journal of the American Academy of Orthopaedic Surgeons, 1995
Management of foot problems in the patient with diabetes mellitus requires attention to each system affected by the disease. Appropriate treatment of common clinical problems affecting the foot in diabetic patients, such as ulcerations and fractures, depends on a thorough understanding of the pathophysiology of the disease.
, Laughlin, , Calhoun, , Mader
openaire   +2 more sources

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